Protein Serine-Threonine Kinases
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Chlamydophila pneumoniae
PknD Exhibits Dual Amino Acid Specificity and Phosphorylates Cpn0712, a Putative Type III Secretion YscD Homolog Academic Article
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IL‐6 mediates ER expansion during hyperpolarization of alternatively activated macrophages Academic Article
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A Multiplex Human Syndrome Implicates a Key Role for Intestinal Cell Kinase in Development of Central Nervous, Skeletal, and Endocrine Systems Academic Article
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A Novel Non-canonical Forkhead-associated (FHA) Domain-binding Interface Mediates the Interaction between Rad53 and Dbf4 Proteins Academic Article
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A Phase I Open-Label Dose-Escalation Study of Intravenous BI 2536 Together With Pemetrexed in Previously Treated Patients With Non–Small-Cell Lung Cancer Academic Article
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A Randomized, Open-Label Phase II Trial of Volasertib as Monotherapy and in Combination With Standard-Dose Pemetrexed Compared With Pemetrexed Monotherapy in Second-Line Treatment for Non–Small-Cell Lung Cancer Academic Article
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A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia Academic Article
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AMP-Activated Protein Kinase Regulates GLUT4 Transcription by Phosphorylating Histone Deacetylase 5 Academic Article
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AMP-activated protein kinase — the fat controller of the energy railroadThis paper is one of a selection of papers published in this Special issue, entitled Second Messengers and Phosphoproteins—12th International Conference. Academic Article
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AMPK expression and phosphorylation are increased in rodent muscle after chronic leptin treatment Academic Article
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ATM activation is accompanied with earlier stages of prostate tumorigenesis Academic Article
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ATM activity contributes to the tumor-suppressing functions of p14ARF Academic Article
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ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes Academic Article
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ATM regulates proteasome-dependent subnuclear localization of TRF1, which is important for telomere maintenance Academic Article
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Aberrant interferon-signaling is associated with aggressive chronic lymphocytic leukemia Academic Article
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Abrogation of MAP4K4 protein function causes congenital anomalies in humans and zebrafish Academic Article
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Abrogation of mesenchyme-specific TGF-β signaling results in lung malformation with prenatal pulmonary cysts in mice Academic Article
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Absence of a differentiation defect in muscle satellite cells from DM2 patients Academic Article
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Activation of TRPM7 by naltriben enhances migration and invasion of glioblastoma cells Academic Article
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Adiponectin: Starving for Attention Academic Article
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Akt Is Activated in Response to an Apoptotic Signal Academic Article
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Akt Mediates Mechanical Strain-Induced Collagen Production by Mesangial Cells Academic Article
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Allelic and phenotypic spectrum of plasma triglycerides Academic Article
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Altered TAOK2 activity causes autism-related neurodevelopmental and cognitive abnormalities through RhoA signaling Academic Article
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Aminoglycoside antibiotic phosphotransferases are also serine protein kinases Academic Article
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An Isoform of the Neuronal Cyclin-dependent Kinase 5 (Cdk5) Activator Academic Article
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Association of Neurofilament Proteins with Neuronal Cdk5 Activator Academic Article
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Bone Morphogenetic Proteins Regulate the Developmental Program of Human Hematopoietic Stem Cells Academic Article
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Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation Academic Article
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Bradykinin stimulates endothelial cell fatty acid oxidation by CaMKK-dependent activation of AMPK Academic Article
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CANTRK Academic Article
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CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection Academic Article
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CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK Academic Article
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Carbohydrate refeeding after a high-fat diet rapidly reverses the adaptive increase in human skeletal muscle PDH kinase activity Academic Article
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Cigarette Smoke Suppresses Type I Interferon-Mediated Antiviral Immunity in Lung Fibroblast and Epithelial Cells Academic Article
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Ciliary Neurotrophic Factor Suppresses Hypothalamic AMP-Kinase Signaling in Leptin-Resistant Obese Mice Academic Article
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Compromised genomic integrity impedes muscle growth after Atrx inactivation Academic Article
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Control of oxygen free radical formation from mitochondrial complex I: roles for protein kinase A and pyruvate dehydrogenase kinase Academic Article
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Cyclin-dependent Kinase 5 (Cdk5) Activation Domain of Neuronal Cdk5 Activator Academic Article
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Cyclin-dependent kinase 5 (Cdk5) and neuron-specific Cdk5 activators Academic Article
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DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants Academic Article
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DRD2/ANKK1 TaqI A genotype moderates the relationship between alexithymia and the relative value of alcohol among male college binge drinkers Academic Article
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Deletion of Macrophage-Specific Glycogen Synthase Kinase (GSK)-3α Promotes Atherosclerotic Regression in Ldlr−/− Mice Academic Article
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Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division Academic Article
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Down-regulated miRs specifically correlate with non-cardial gastric cancers and Lauren's classification system Academic Article
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Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells Academic Article
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ERK Activation Mediates Cell Cycle Arrest and Apoptosis after DNA Damage Independently of p53 Academic Article
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ERK activity facilitates activation of the S-phase DNA damage checkpoint by modulating ATR function Academic Article
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ERK1 and ERK2 kinases activate hydroxyurea-induced S-phase checkpoint in MCF7 cells by mediating ATR activation Academic Article
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Effects of aerobic training on pyruvate dehydrogenase and pyruvate dehydrogenase kinase in human skeletal muscle Academic Article
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Elevated n-3 fatty acids in a high-fat diet attenuate the increase in PDH kinase activity but not PDH activity in human skeletal muscle Academic Article
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Epithelium-specific adenoviral transfer of a dominant-negative mutant TGF-β type II receptor stimulates embryonic lung branching morphogenesis in culture and potentiates EGF and PDGF-AA Academic Article
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Establishing a relationship between prolactin and altered fatty acid β-Oxidation via carnitine palmitoyl transferase 1 in breast cancer cells Academic Article
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Excitation-contraction coupling in pulmonary vascular smooth muscle involves tyrosine kinase and Rho kinase Academic Article
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Exercising women throw a wrench in the gears of the AMPK-lipid oxidation link Academic Article
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Expression of recombinant human casein kinase II and recombinant heat shock protein 90 in Escherichia coli and characterization of their interactions. Academic Article
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Fatty acids stimulate AMP-activated protein kinase and enhance fatty acid oxidation in L6 myotubes Academic Article
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Functional analysis of CfSnf1 in the development and pathogenicity of anthracnose fungus Colletotrichum fructicola on tea-oil tree Academic Article
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G Protein-coupled Receptor Kinase-mediated Desensitization of Metabotropic Glutamate Receptor 1A Protects against Cell Death Academic Article
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Genetic determinants of plasma triglycerides Academic Article
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Genetic influences on delay discounting in smokers: examination of a priori candidates and exploration of dopamine-related haplotypes Academic Article
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Glucose transporter expression in L6 muscle cells: Regulation through insulin- and stress-activated pathways Academic Article
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Glycosyltransferases and Glycosaminoglycans in Bleomycin and Transforming Growth Factor-β1–Induced Pulmonary Fibrosis Academic Article
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Guanosine protects SH-SY5Y cells against β-amyloid-induced apoptosis Academic Article
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HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function Academic Article
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Hierarchical investigation of genetic influences on response inhibition in healthy young adults. Academic Article
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Hippo pathway dysregulation in gastric cancer: from Helicobacter pylori infection to tumor promotion and progression Academic Article
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Human skeletal muscle PDH kinase activity and isoform expression during a 3-day high-fat/low-carbohydrate diet Academic Article
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Human skeletal muscle pyruvate dehydrogenase kinase activity increases after a low-carbohydrate diet Academic Article
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Hyperglycemia Exacerbates Burn-Induced Liver Inflammation via Noncanonical Nuclear Factor-κB Pathway Activation Academic Article
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Identification of MEK- and phosphoinositide 3-kinase-dependent signalling as essential events during Chlamydia pneumoniae invasion of HEp2 cells Academic Article
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Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpression Academic Article
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Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition Academic Article
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Inflammation promotes adipocyte lipolysis via IRE1 kinase Academic Article
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Inhibition of apoptosis in human induced pluripotent stem cells during expansion in a defined culture using angiopoietin-1 derived peptide QHREDGS Academic Article
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Insulin Activates a p21-activated Kinase in Muscle Cells via Phosphatidylinositol 3-Kinase Academic Article
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Insulin, Insulin-like Growth Factor-I, and Platelet-Derived Growth Factor Activate Extracellular Signal-Regulated Kinase by Distinct Pathways in Muscle Cells Academic Article
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Interaction of Cyclin-dependent Kinase 5 (Cdk5) and Neuronal Cdk5 Activator in Bovine Brain Academic Article
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Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase Academic Article
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Ionizing Radiation Activates AMP-Activated Kinase (AMPK): A Target for Radiosensitization of Human Cancer Cells Academic Article
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Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling Academic Article
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KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase Academic Article
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Liver kinase B1 expression (LKB1) is repressed by estrogen receptor alpha (ERα) in MCF-7 human breast cancer cells Academic Article
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Loss of Hepatocyte-Nuclear-Factor-1α Impacts on Adult Mouse Intestinal Epithelial Cell Growth and Cell Lineages Differentiation Academic Article
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Loss of expression of bone morphogenetic protein receptor type II in human prostate cancer cells Academic Article
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MRE11–RAD50–NBS1 and ATM function as co-mediators of TRF1 in telomere length control Academic Article
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Maternal Embryonic Leucine Zipper Kinase Is Upregulated and Required in Mammary Tumor-Initiating Cells In vivo Academic Article
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Melatonin and Hippo Pathway: Is There Existing Cross-Talk? Academic Article
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Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation Academic Article
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Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK Academic Article
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Mirk/Dyrk1b Mediates Cell Survival in Rhabdomyosarcomas Academic Article
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Mitogen-activated protein kinases Erk1/2 and p38 are required for maximal regulation of TIMP-1 by oncostatin M in murine fibroblasts Academic Article
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Multiple Signaling Pathways Control the Activation of the CEF-4/9E3 Cytokine Gene by pp60v- Academic Article
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Multiple genes in human 20q13 chromosomal region are involved in an advanced prostate cancer xenograft. Academic Article
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Muscarinic excitation-contraction coupling mechanisms in tracheal and bronchial smooth muscles Academic Article
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Muscle fiber type comparison of PDH kinase activity and isoform expression in fed and fasted rats Academic Article
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Mutant p53 Protein and the Hippo Transducers YAP and TAZ: A Critical Oncogenic Node in Human Cancers Academic Article
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Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop Academic Article
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Mutations in TBCK, Encoding TBC1-Domain-Containing Kinase, Lead to a Recognizable Syndrome of Intellectual Disability and Hypotonia Academic Article
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NCAM1-TTC12-ANKK1-DRD2 variants and smoking motives as intermediate phenotypes for nicotine dependence Academic Article
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Negative Regulation of β4 Integrin Transcription by Homeodomain-Interacting Protein Kinase 2 and p53 Impairs Tumor Progression Academic Article
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Neuronal Cdc2-like kinase: from cell cycle to neuronal function Academic Article
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Non-digestible oligosaccharides directly regulate host kinome to modulate host inflammatory responses without alterations in the gut microbiota Academic Article
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Novel Function of PERK as a Mediator of Force-induced Apoptosis Academic Article
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Nuclear Import of Cdk/Cyclin Complexes: Identification of Distinct Mechanisms for Import of Cdk2/Cyclin E and Cdc2/Cyclin B1 Academic Article
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Nuclear Targeting of Methyl-Recycling Enzymes in Arabidopsis thaliana Is Mediated by Specific Protein Interactions Academic Article
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Nucleotide Selectivity of Antibiotic Kinases Academic Article
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Paternal transmission of the congenital form of myotonic dystrophy type 1: A new case and review of the literature Academic Article
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Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children Academic Article
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Pharmacologic inhibition of S1P attenuates ATF6 expression, causes ER stress and contributes to apoptotic cell death Academic Article
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Phosphorylation of PITSLRE p110 Isoforms Accompanies Their Processing by Caspases during Fas-mediated Cell Death Academic Article
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Polo-Like Kinase 1 Inhibition Kills Glioblastoma Multiforme Brain Tumor Cells in Part Through Loss of SOX2 and Delays Tumor Progression in Mice Academic Article
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Polo-like kinases in AML Academic Article
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Polygenic determinants of severe hypertriglyceridemia Academic Article
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Progressive Transforming Growth Factor β1–induced Lung Fibrosis Is Blocked by an Orally Active ALK5 Kinase Inhibitor Academic Article
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Pyruvate overrides inhibition of PDH during exercise after a low-carbohydrate diet Academic Article
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Rapid upregulation of pyruvate dehydrogenase kinase activity in human skeletal muscle during prolonged exercise Academic Article
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Reduced glycogen availability is associated with increased AMPKα2 activity, nuclear AMPKα2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle Academic Article
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Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue Academic Article
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Regulation of NADH/CoQ Oxidoreductase: Do Phosphorylation Events Affect Activity? Academic Article
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Regulation of Rho/ROCK signaling in airway smooth muscle by membrane potential and [Ca2+]i Academic Article
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Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli Academic Article
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Regulation of airway smooth muscle RhoA/ROCK activities by cholinergic and bronchodilator stimuli. Academic Article
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Regulatory properties of neuronal cdc2-like kinase Academic Article
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Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers Academic Article
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Reversible Dysfunction of Wild-Type p53 following Homeodomain-Interacting Protein Kinase-2 Knockdown Academic Article
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Role of PRY-1/Axin in heterochronic miRNA-mediated seam cell development Academic Article
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S6K-STING interaction regulates cytosolic DNA–mediated activation of the transcription factor IRF3 Academic Article
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Selective involvement of the PI3K/PKB/bad pathway in retinal cell death Academic Article
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Semaphorin 3F Antagonizes Neurotrophin-Induced Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase Kinase Signaling: A Mechanism for Growth Cone Collapse Academic Article
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Serum- and Glucocorticoid-Regulated Kinase 1 Is Required for Nuclear Export of the Ribonucleoprotein of Influenza A Virus Academic Article
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Signals for local and systemic responses of plants to pathogen attack Academic Article
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Skeletal muscle metabolism is unaffected by DCA infusion and hyperoxia after onset of intense aerobic exercise Academic Article
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Spinal Myxopapillary Ependymomas Demonstrate a Warburg Phenotype Academic Article
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Sterol Regulatory Element Binding Protein (SREBP)-1 is a novel regulator of the Transforming Growth Factor (TGF)-β receptor I (TβRI) through exosomal secretion Academic Article
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StoPK-1, a serine/threonine protein kinase from the glycopeptide antibiotic producer Streptomyces toyocaensis NRRL 15009, affects oxidative stress response Academic Article
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Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy. Academic Article
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Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf Academic Article
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Systematic Discovery of TLR Signaling Components Delineates Viral-Sensing Circuits Academic Article
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TAOK2 rescues autism-linked developmental deficits in a 16p11.2 microdeletion mouse model Academic Article
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TGF- receptor II in epithelia versus mesenchyme plays distinct roles in the developing lung Academic Article
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TGF-β and Smad3 Signaling Link Inflammation to Chronic Fibrogenesis Academic Article
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The AMP-Activated Protein Kinase: Role in Regulation of Skeletal Muscle Metabolism and Insulin Sensitivity Academic Article
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The Hippo tumor suppressor pathway: a report on ‘the second workshop on the Hippo tumor suppressor pathway’ Academic Article
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The Stimulatory Effect of Globular Adiponectin on Insulin-Stimulated Glucose Uptake and Fatty Acid Oxidation Is Impaired in Skeletal Muscle From Obese Subjects Academic Article
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The activity of the Ets transcription factor PEA3 is regulated by two distinct MAPK cascades. Academic Article
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The acute effects of differential dietary fatty acids on human skeletal muscle pyruvate dehydrogenase activity Academic Article
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The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes Academic Article
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The gene transfer of soluble VEGF type I receptor (Flt-1) attenuates peritoneal fibrosis formation in mice but not soluble TGF-β type II receptor gene transfer Academic Article
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The lnterleukin-5/Receptor Interaction Activates Lyn and Jak2 Tyrosine Kinases and Propagates Signals via the Ras-Raf-1-MAP Kinase and the Jak-STAT Pathways in Eosinophils Conference Paper
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The p38-MK2-HuR pathway potentiates EGFRvIII–IL-1β-driven IL-6 secretion in glioblastoma cells Academic Article
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The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity Academic Article
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The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells Academic Article
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The unfolded protein response is triggered following a single, unaccustomed resistance-exercise bout Academic Article
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Therapeutic Targeting of the Premetastatic Stage in Human Lung-to-Brain Metastasis Academic Article
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Underexpression of tumour suppressor LKB1 in clear cell renal cell carcinoma is common and confers growth advantage in vitro and in vivo Academic Article
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Vasoconstrictor actions of isoprostanes via
tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles Academic Article
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Whole Blood Gene Expression Differentiates between Atrial Fibrillation and Sinus Rhythm after Cardioversion Academic Article
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Whole-exome sequencing is a valuable diagnostic tool for inherited peripheral neuropathies: Outcomes from a cohort of 50 families Academic Article
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YAP1 Meets Tumor Suppression Academic Article
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miRNA in the Regulation of Skeletal Muscle Adaptation to Acute Endurance Exercise in C57Bl/6J Male Mice Academic Article
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miR‐10b*, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours Academic Article
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β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer Academic Article
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β‐adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling Academic Article