Journal article
Whole Blood Gene Expression Differentiates between Atrial Fibrillation and Sinus Rhythm after Cardioversion
Abstract
BACKGROUND: Treatment to restore sinus rhythm among patients with atrial fibrillation (AF) has limited long-term success rates. Gene expression profiling may provide new insights into AF pathophysiology.
OBJECTIVE: To identify biomarkers and improve our understanding of AF pathophysiology by comparing whole blood gene expression before and after electrical cardioversion (ECV).
Authors
Raman K; Aeschbacher S; Bossard M; Hochgruber T; Zimmermann AJ; Kaufmann BA; Pumpol K; Rickenbacker P; Paré G; Conen D
Journal
PLOS ONE, Vol. 11, No. 6,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0157550
ISSN
1932-6203
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedArrhythmia, SinusAtrial FibrillationBiomarkersCohort StudiesDemographyDiagnosis, DifferentialElectric CountershockFemaleGene Expression RegulationHumansMaleMembrane Transport ProteinsNatriuretic Peptide, BrainProtein Serine-Threonine KinasesPyruvate Dehydrogenase Acetyl-Transferring KinaseReproducibility of Results