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Identification of post-transcriptional regulatory...
Journal article

Identification of post-transcriptional regulatory networks during myeloblast-to-monocyte differentiation transition

Abstract

Treatment of leukemia cells with 1,25-dihydroxyvitamin D3 may overcome their differentiation block and lead to the transition from myeloblasts to monocytes. To identify microRNA-mRNA networks relevant for myeloid differentiation, we profiled the expression of mRNAs and microRNAs associated to the low- and high-density ribosomal fractions in leukemic cells and in their differentiated monocytic counterpart. Intersection between mRNAs shifted …

Authors

Fontemaggi G; Bellissimo T; Donzelli S; Iosue I; Benassi B; Bellotti G; Blandino G; Fazi F

Journal

RNA Biology, Vol. 12, No. 7, pp. 690–700

Publisher

Taylor & Francis

Publication Date

July 3, 2015

DOI

10.1080/15476286.2015.1044194

ISSN

1547-6286