Journal article
Down‐regulated miRs specifically correlate with non‐cardial gastric cancers and Lauren's classification system
Abstract
BACKGROUND AND OBJECTIVES: Gastric cancers are usually characterized using Lauren's classification into intestinal and diffuse types. We previously documented the down-modulation of miR31, miR148a, miR204, and miR375 in gastric cancers. We aimed this manuscript to investigate these miRs with the end-points of diagnosis, Lauren's classification and prognosis.
METHODS: A total of 117 resected non-cardial adenocarcinomas were evaluated for miRs' …
Authors
Lorenzon L; Cippitelli C; Avantifiori R; Uccini S; French D; Torrisi MR; Ranieri D; Mercantini P; Canu V; Blandino G
Journal
Journal of Surgical Oncology, Vol. 116, No. 2, pp. 184–194
Publisher
Wiley
Publication Date
August 2017
DOI
10.1002/jso.24648
ISSN
0022-4790
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdenocarcinomaAdultAge FactorsAgedAged, 80 and overCell Line, TumorDown-RegulationFemaleGene Expression Regulation, NeoplasticHumansJanus Kinase 2MaleMicroRNAsMiddle AgedPrognosisProtein Serine-Threonine KinasesProto-Oncogene Proteins c-bcl-2Pyruvate Dehydrogenase Acetyl-Transferring KinaseROC CurveRepressor ProteinsRetrospective StudiesSensitivity and SpecificitySex FactorsStomach Neoplasms