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Role of PRY-1/Axin in heterochronic miRNA-mediated...
Journal article

Role of PRY-1/Axin in heterochronic miRNA-mediated seam cell development

Abstract

BackgroundCaenorhabditis elegans seam cells serve as a good model to understand how genes and signaling pathways interact to control asymmetric cell fates. The stage-specific pattern of seam cell division is coordinated by a genetic network that includes WNT asymmetry pathway components WRM-1, LIT-1, and POP-1, as well as heterochronic microRNAs (miRNAs) and their downstream targets. Mutations in pry-1, a negative regulator of WNT signaling …

Authors

Mallick A; Ranawade A; Gupta BP

Journal

BMC Developmental Biology, Vol. 19, No. 1,

Publisher

Springer Nature

Publication Date

December 2019

DOI

10.1186/s12861-019-0197-5

ISSN

1471-213X