Pyridines Concept

subject area of

• In vivo and in vitro Validation of Reference Tissue Models for the mGluR₅ Ligand [¹¹C]ABP688  Academic Article
• A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis  Academic Article
• A PET study of effects of chronic 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) on serotonin markers in Göttingen minipig brain  Academic Article
• A Phase II study of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) and gemcitabine in advanced pancreatic carcinoma. A trial of the Princess Margaret Hospital Phase II consortium  Academic Article
• A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: The Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt (RE-ALIGN)  Academic Article
• A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis  Academic Article
• A logical approach to surgical thromboprophylaxis  Academic Article
• A medium-throughput functional assay of KCNQ2 potassium channels using rubidium efflux and atomic absorption spectrometry  Academic Article
• A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers  Academic Article
• A phase II study of sorafenib in advanced uterine carcinoma/carcinosarcoma: A trial of the Chicago, PMH, and California Phase II Consortia  Academic Article
• A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer  Academic Article
• A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer  Academic Article
• A phase II trial of sorafenib in first-line metastatic urothelial cancer: a study of the PMH Phase II Consortium  Academic Article
• A placebo-controlled study to determine the efficacy of oral disopyramide phosphate for the prophylaxis of ventricular dysrhythmias after acute myocardial infarction.  Academic Article
• A prospective evaluation of edoxaban compared to warfarin in subjects undergoing cardioversion of atrial fibrillation: The EdoxabaN vs. warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study  Academic Article
• A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study  Academic Article
• Absorption and antidysrhythmic activity of oral disopyramide phosphate after acute myocardial infarction.  Academic Article
• Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine—A Multicenter Trial  Academic Article
• Action of mianserin and zimelidine on the norepinephrine receptor coupled adenylate cyclase system in brain: Subsensitivity without reduction in β-adrenergic receptor binding  Academic Article
• Activated Clotting Time to Guide Heparin Dosing in Non–ST-Segment–Elevation Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention and Treated With IIb/IIIa Inhibitors  Academic Article
• Activation of p38 mitogen-activated protein kinase during normal mitosis in the developing retina  Academic Article
• Activity of cabozantinib after immune checkpoint blockade in metastatic clear-cell renal cell carcinoma  Academic Article
• Advantages and limitations of the new anticoagulants  Academic Article
• Andexanet Alfa for Specific Anticoagulation Reversal in Patients with Acute Bleeding during Treatment with Edoxaban  Academic Article
• Anticoagulation With Otamixaban and Ischemic Events in Non–ST-Segment Elevation Acute Coronary Syndromes  Academic Article
• Antiplatelet Drugs  Academic Article
• Antithrombotic Therapy During Percutaneous Coronary Intervention  Academic Article
• Antithrombotic treatment for peripheral arterial disease  Academic Article
• Assaying Small-Molecule−Receptor Interactions by Continuous Flow Competitive Displacement Chromatography/Mass Spectrometry  Academic Article
• BAY 43-9006: Early Clinical Data in Patients with Advanced Solid Malignancies  Academic Article
• Betrixaban (PRT054021): pharmacology, dose selection and clinical studies  Academic Article
• Betrixaban compared with warfarin in patients with atrial fibrillation: results of a phase 2, randomized, dose-ranging study (Explore-Xa)  Academic Article
• Beyond Unfractionated Heparin and Warfarin  Academic Article
• Biosynthesis of Vitamin B₁ in Yeast. Derivation of the Pyrimidine Unit from Pyridoxine and Histidine. Intermediacy of Urocanic Acid  Academic Article
• Bivariate evaluation of thromboembolism and bleeding in clinical trials of anticoagulants in patients with atrial fibrillation  Academic Article
• Bleeding and antidotes in new oral anticoagulants  Academic Article
• Bleeding with Direct Oral Anticoagulants vs Warfarin: Clinical Experience  Academic Article
• Bleeding with direct oral anticoagulants vs warfarin: clinical experience  Academic Article
• Cabozantinib for Progressive Metastatic Castration-resistant Prostate Cancer Following Docetaxel: Combined Analysis of Two Phase 3 Trials  Academic Article
• Cabozantinib real‐world effectiveness in the first‐through fourth‐line settings for the treatment of metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium  Academic Article
• Cerivastatin versus branded pravastatin in the treatment of primary hypercholesterolemia in primary care practice in Canada: A one-year, open-label, randomized, comparative study of efficacy, safety, and cost-effectiveness  Academic Article
• Changes in Renal Function in Patients With Atrial Fibrillation  Academic Article
• Clinical Experience With the New Oral Anticoagulants for Treatment of Venous Thromboembolism  Academic Article
• Clinical Impact of Bleeding in Cancer-Associated Venous Thromboembolism: Results from the Hokusai VTE Cancer Study  Academic Article
• Clinical evaluation of the efficacy and safety of noberastine, a new H1 antagonist, in seasonal allergic rhinitis: A placebo-controlled, dose-response study  Academic Article
• Clinical implications of reversal agents for direct oral anticoagulants  Academic Article
• Clopidogrel and percutaneous coronary intervention  Academic Article
• Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer  Academic Article
• Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development  Academic Article
• Comparison of Fatal or Irreversible Events With Extended‐Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy  Academic Article
• Comparison of the effects of omapatrilat and lisinopril on circulating neurohormones and cytokines in patients with chronic heart failure  Academic Article
• Complementary studies of the gastrointestinal safety of the cyclo-oxygenase-2-selective inhibitor etoricoxib  Academic Article
• Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle  Academic Article
• Concomitant Use of Antiplatelet Therapy with Dabigatran or Warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Trial  Academic Article
• Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: A combined α-[11C]MT and [18F]MPPF positron emission tomography study  Conference Paper
• Cost Effectiveness of EML4-ALK Fusion Testing and First-Line Crizotinib Treatment for Patients With Advanced ALK-Positive Non–Small-Cell Lung Cancer  Academic Article
• Cost-effectiveness of dabigatran etexilate for the prevention of stroke and systemic embolism in atrial fibrillation: A Canadian payer perspective  Academic Article
• Dabigatran Etexilate  Academic Article
• Dabigatran Etexilate: Future Directions in Anticoagulant Treatment  Academic Article
• Dabigatran Versus Warfarin  Academic Article
• Dabigatran and Warfarin in Vitamin K Antagonist–Naive and –Experienced Cohorts With Atrial Fibrillation  Academic Article
• Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial  Academic Article
• Dabigatran etexilate for prevention of venous thromboembolism  Academic Article
• Dabigatran for stroke prevention in atrial fibrillation: the RE-LY trial  Academic Article
• Dabigatran versus Warfarin for Venous Thromboembolism  Academic Article
• Dabigatran versus Warfarin in Patients with Atrial Fibrillation  Academic Article
• Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism  Academic Article
• Dabigatran: ready for prime time?  Academic Article
• Design and rationale of the Treatment of Acute Coronary Syndromes with Otamixaban trial: A double-blind triple-dummy 2-stage randomized trial comparing otamixaban to unfractionated heparin and eptifibatide in non–ST-segment elevation acute coronary syndromes with a planned early invasive strategy  Academic Article
• Determination and visualization of damage to striatal dopaminergic terminals in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism by [18F]-labeled 6-fluoro-L-dopa and positron emission tomography.  Academic Article
• Determination of pyridine and adenine nucleotide metabolites in Bacillus subtilis cell extract by sweeping borate complexation capillary electrophoresis  Academic Article
• Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials.  Academic Article
• Direct oral anticoagulants: evidence and unresolved issues  Academic Article
• Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA  Academic Article
• Dose reduction of edoxaban preserves efficacy and safety for the treatment of venous thromboembolism  Academic Article
• Drug release by pH-responsive molecular tweezers: Atomistic details from molecular modeling  Academic Article
• ENNOBLE-ATE trial: an open-label, randomised, multi-centre, observational study of edoxaban for children with cardiac diseases at risk of thromboembolism  Academic Article
• ERG K⁺ currents regulate pacemaker activity in ICC  Academic Article
• Editorial: healing of refractory reflux oesophagitis - an ongoing unmet clinical need  Academic Article
• Edoxaban and amiodarone: interactions on multiple levels  Academic Article
• Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism  Academic Article
• Edoxaban for the Treatment of Venous Thromboembolism in Patients with Cancer  Academic Article
• Edoxaban for treatment of venous thromboembolism in patient groups with different types of cancer: Results from the Hokusai VTE Cancer study  Academic Article
• Edoxaban for treatment of venous thromboembolism in patients with cancer  Academic Article
• Edoxaban for venous thromboembolism in patients with cancer: results from a non-inferiority subgroup analysis of the Hokusai-VTE randomised, double-blind, double-dummy trial  Academic Article
• Edoxaban is non-inferior to low-molecular-weight heparin for treating cancer-associated venous thromboembolism  Academic Article
• Edoxaban versus Warfarin in Patients with Atrial Fibrillation  Academic Article
• Edoxaban versus enoxaparin–warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF): a randomised, open-label, phase 3b trial  Academic Article
• Effect of a new nootropic agent, CGS 5649B, on cognition, function, and behavior in dementia  Academic Article
• Effect of extended‐duration thromboprophylaxis on venous thromboembolism and major bleeding among acutely ill hospitalized medical patients: a bivariate analysis  Academic Article
• Effect on Intragastric pH of a PPI with a Prolonged Plasma Half-Life: Comparison between Tenatoprazole and Esomeprazole on the Duration of Acid Suppression in Healthy Male Volunteers  Academic Article
• Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma  Academic Article
• Effects of pumaprazole (BY841), a novel reversible proton pump antagonist, and of omeprazole, on intragastric acidity before and after cure of Helicobacter pylori infection  Academic Article
• Effects of the thromboxane synthetase inhibitor and receptor antagonist terbogrel in patients with primary pulmonary hypertension  Academic Article
• Efficacy and Safety of Fondaparinux Versus Enoxaparin in Patients With Acute Coronary Syndromes Treated With Glycoprotein IIb/IIIa Inhibitors or Thienopyridines  Academic Article
• Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial  Academic Article
• Efficacy of 5-HT3 Antagonists and 5-HT4 Agonists in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis  Academic Article
• Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret  Academic Article
• Endothelium-dependent relaxation factor released by perivascular adipose tissue  Academic Article
• Enhancing Endocrine Therapy Combination Strategies for the Treatment of Postmenopausal HR+/HER2– Advanced Breast Cancer  Academic Article
• Epigenetic therapy inhibits metastases by disrupting premetastatic niches  Academic Article
• Ether-a-go-go-related gene 3 is the main candidate for the E-4031-sensitive potassium current in the pacemaker interstitial cells of Cajal  Academic Article
• Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.  Academic Article
• Evolving use of new oral anticoagulants for treatment of venous thromboembolism  Academic Article
• Experimental porphyria. I. The experimental porphyrias--a group of distinctive metabolic lesions.  Academic Article
• Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients  Academic Article
• Extended duration of anticoagulation with edoxaban in patients with venous thromboembolism: a post-hoc analysis of the Hokusai-VTE study  Academic Article
• Extended treatment with edoxaban in cancer patients with venous thromboembolism: A post‐hoc analysis of the Hokusai‐VTE Cancer study  Academic Article
• Factor Xa and thrombin as targets for new oral anticoagulants  Academic Article
• Factors affecting antiretroviral pharmacokinetics in HIV-infected women with virologic suppression on combination antiretroviral therapy: a cross-sectional study  Academic Article
• Fluorescence photometric determination of disopyramide and mono-N-dealkylated disopyramide in plasma after separation by thin-layer chromatography  Academic Article
• Fostamatinib for the treatment of adult persistent and chronic immune thrombocytopenia: Results of two phase 3, randomized, placebo-controlled trials  Academic Article
• Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open‐label study  Academic Article
• Functional subtyping of histamine receptors on the canine proximal colonic mucosa.  Academic Article
• Gastrointestinal Bleeding With Edoxaban Versus Warfarin  Academic Article
• Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding  Academic Article
• Global Gastrointestinal Safety Profile of Etoricoxib and Lumiracoxib  Academic Article
• Guidelines for vismodegib in the management of periocular basal cell carcinoma  Academic Article
• HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants  Academic Article
• HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity  Academic Article
• Human airway smooth muscle promotes eosinophil differentiation  Academic Article
• Hypoxia-Induced Lactate Dehydrogenase Expression and Tumor Angiogenesis  Academic Article
• Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development  Academic Article
• Impact of Spontaneous Extracranial Bleeding Events on Health State Utility in Patients with Atrial Fibrillation: Results from the ENGAGE AF‐TIMI 48 Trial  Academic Article
• Impact of age, comorbidity, and polypharmacy on the efficacy and safety of edoxaban for the treatment of venous thromboembolism: An analysis of the randomized, double-blind Hokusai-VTE trial  Academic Article
• In vivo hippocampal cornu ammonis 1–3 glutamatergic abnormalities are associated with temporal lobe epilepsy surgery outcomes  Academic Article
• Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation  Academic Article
• Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice  Academic Article
• Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin  Academic Article
• International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants  Academic Article
• Is There a Role for Betrixaban to Prevent Stroke in Medically Ill Patients?  Academic Article
• Ischaemic and bleeding risk in atrial fibrillation with and without peripheral artery disease and efficacy and safety of full- and half-dose edoxaban vs. warfarin: insights from ENGAGE AF-TIMI 48  Academic Article
• Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca²⁺ handling and Rho/ROCK signaling  Academic Article
• KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase  Academic Article
• Laboratory Monitoring of Non–Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation  Academic Article
• Laboratory measurement of the direct oral anticoagulants  Academic Article
• Lack of Hormonal Effects of a Single Dose of Nifedipine in Healthy Young Me  Academic Article
• Linking Endogenous Factor Xa Activity, a Biologically Relevant Pharmacodynamic Marker, to Edoxaban Plasma Concentrations and Clinical Outcomes in the ENGAGE AF-TIMI 48 Trial  Academic Article
• Long‐term fostamatinib treatment of adults with immune thrombocytopenia during the phase 3 clinical trial program  Academic Article
• MN-166 (ibudilast) in amyotrophic lateral sclerosis in a Phase IIb/III study: COMBAT-ALS study design  Academic Article
• Magnetic resonance venography to assess thrombus resolution with edoxaban monotherapy versus parenteral anticoagulation/warfarin for symptomatic deep vein thrombosis: A multicenter feasibility study  Academic Article
• Mechanisms of apoptosis induced by purine nucleosides in astrocytes  Academic Article
• Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation  Academic Article
• Metabolic Myopathies Discovered During Investigations of Statin Myopathy  Academic Article
• Metastatic Renal Carcinoma: Evaluation of Antiangiogenic Therapy with Dynamic Contrast-enhanced CT  Academic Article
• Metastatic renal cell cancer treatments: An indirect comparison meta-analysis  Academic Article
• Monitoring and reversal of direct oral anticoagulants  Academic Article
• NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank  Academic Article
• New Anticoagulants for Atrial Fibrillation  Academic Article
• New Anticoagulants for Treatment of Venous Thromboembolism  Academic Article
• New Anticoagulants for the Prevention of Thromboembolism  Academic Article
• New anticoagulants  Conference Paper
• New aspects on treatment modalities for thromboembolic episodes  Academic Article
• New oral anticoagulant agents – general features and outcomes in subsets of patients  Academic Article
• New oral anticoagulants for stroke prevention in atrial fibrillation: impact of study design, double counting and unexpected findings on interpretation of study results and conclusions  Academic Article
• New oral anticoagulants for thromboprophylaxis in patients having hip or knee arthroplasty  Academic Article
• New oral anticoagulants in elderly patients  Academic Article
• New oral anticoagulants: not quite there yet  Academic Article
• Newly Identified Events in the RE-LY Trial  Academic Article
• Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells  Academic Article
• Novel Oral Anticoagulants: A Focused Review for Stroke Physicians  Academic Article
• Novel Oral Factor Xa and Thrombin Inhibitors in the Management of Thromboembolism  Academic Article
• Novel oral anticoagulants in gastroenterology practice  Academic Article
• Optimizing the safety of treatment for venous thromboembolism in the era of the direct oral anticoagulants  Academic Article
• Oral Anticoagulant Therapy  Academic Article
• Oral Direct Factor Xa Inhibitors  Academic Article
• Oral anticoagulants in coronary heart disease (Section IV) Position paper of the ESC Working Group on Thrombosis – Task Force on Anticoagulants in Heart Disease  Academic Article
• Oral bisphosphonates  Academic Article
• Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement  Academic Article
• Otamixaban in acute coronary syndromes  Academic Article
• Outpatient Management in Patients with Venous Thromboembolism with Edoxaban: A Post Hoc Analysis of the Hokusai-VTE Study  Academic Article
• Overview of the New Oral Anticoagulants  Academic Article
• Ozone Inhalation Provokes Glucocorticoid-Dependent and -Independent Effects on Inflammatory and Metabolic Pathways  Academic Article
• Palbociclib in hormone receptor positive advanced breast cancer: A cost-utility analysis  Academic Article
• Palbociclib plus letrozole versus placebo plus letrozole in Asian postmenopausal women with oestrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer: Primary results from PALOMA-4  Academic Article
• Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial  Academic Article
• Periprocedural antithrombotic and bridging therapy: recommendations for standardized reporting in patients with arterial indications for chronic oral anticoagulant therapy  Academic Article
• Pharmacokinetics, safety, activity, and biomarker analysis of palbociclib plus letrozole as first-line treatment for ER+/HER2– advanced breast cancer in Chinese women  Academic Article
• Phase 1 clinical trial of losmapimod in facioscapulohumeral dystrophy: Safety, tolerability, pharmacokinetics, and target engagement  Academic Article
• Phase I Targeted Combination Trial of Sorafenib and Erlotinib in Patients with Advanced Solid Tumors  Academic Article
• Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors  Academic Article
• Phase II Trial of Sorafenib in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Nasopharyngeal Carcinoma  Conference Paper
• Phase II study of Triapine® in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)  Academic Article
• Polymer-Grafted Cellulose Nanocrystals as pH-Responsive Reversible Flocculants  Academic Article
• Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non‐valvular atrial fibrillation from the RE‐LY trial  Academic Article
• Potential of new anticoagulants in patients with cancer  Academic Article
• Practical use of dabigatran etexilate for stroke prevention in atrial fibrillation  Academic Article
• Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism  Academic Article
• Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate  Academic Article
• Pyriproxyfen induces intracellular calcium overload and alters antioxidant defenses in Danio rerio testis that may influence ongoing spermatogenesis  Academic Article
• Quality of Life Outcomes for Cabozantinib Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma: METEOR Phase III Randomized Trial  Academic Article
• Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation  Academic Article
• Randomized, Double-Blind Comparison of Half-Dose Versus Full-Dose Edoxaban in 14,014 Patients With Atrial Fibrillation  Academic Article
• Randomized, Placebo-Controlled, Phase III Study of First-Line Oxaliplatin-Based Chemotherapy Plus PTK787/ZK 222584, an Oral Vascular Endothelial Growth Factor Receptor Inhibitor, in Patients With Metastatic Colorectal Adenocarcinoma  Academic Article
• Rationale and design of RE-LY: Randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran  Academic Article
• Receptor subtypes mediating spinal cardiovascular effects of angiotensin II in rat using losartan and PD 123319  Academic Article
• Recurrent venous thromboembolism in patients with pulmonary embolism and right ventricular dysfunction: a post-hoc analysis of the Hokusai-VTE study  Academic Article
• Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid  Academic Article
• Reply: regarding the effect of dabigatran plasma concentrations.  Academic Article
• Reversal of Direct Oral Anticoagulants: Current Status and Future Directions  Academic Article
• Reversible Cabozantinib-Induced Cardiomyopathy  Academic Article
• Risk factors for gastrointestinal bleeding in patients with gastrointestinal cancer using edoxaban  Academic Article
• Rivaroxaban for the prevention and treatment of venous thromboembolism  Academic Article
• SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction  Academic Article
• SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis  Academic Article
• Safety and Efficacy of Sorafenib in Elderly Patients Treated in the North American Advanced Renal Cell Carcinoma Sorafenib Expanded Access Program  Academic Article
• Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America  Academic Article
• Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Sorafenib: A Review of Four Phase I Trials in Patients with Advanced Refractory Solid Tumors  Academic Article
• Second‐line treatment of hepatocellular carcinoma after sorafenib: Characterizing treatments used over the past 10 years and real‐world eligibility for cabozantinib, regorafenib, and ramucirumab  Academic Article
• Selective potentiating effect of RS14203 on a serotoninergic pathway in anesthetized rats  Academic Article
• Sensitivity of the early-life stages of freshwater mollusks to neonicotinoid and butenolide insecticides  Academic Article
• Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non-vitamin K antagonist oral anticoagulant dose adjustment  Academic Article
• Sorafenib and Radiation Therapy for the Treatment of Advanced Hepatocellular Carcinoma  Academic Article
• Sorafenib in Combination With Gemcitabine in Recurrent Epithelial Ovarian Cancer: A Study of the Princess Margaret Hospital Phase II Consortium  Academic Article
• Stroke prevention in AF: Of Asians and non-Asians  Academic Article
• Stroke prevention in atrial fibrillation: Closing the gap  Academic Article
• Stroke prevention in elderly patients with atrial fibrillation: challenges for anticoagulation  Academic Article
• Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability  Academic Article
• TCF/LEF regulation of the topologically associated domain ADI promotes mESCs to exit the pluripotent ground state  Academic Article
• TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻secretion blocked by a p38 MAPK inhibitor  Academic Article
• The CHORUS (Cerivastatin in Heart Outcomes in Renal Disease: Understanding Survival) protocol: a double-blind, placebo-controlled trial in patients with esrd.  Academic Article
• The Dissociation into Subunits of Aspartate Aminotransferase from Pig Heart Muscle  Academic Article
• The Effect of Dabigatran Plasma Concentrations and Patient Characteristics on the Frequency of Ischemic Stroke and Major Bleeding in Atrial Fibrillation Patients  Academic Article
• The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO  Academic Article
• The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations  Academic Article
• The Pursuit of Clinically Relevant Measures of Platelet Function After Antiplatelet Drug Therapy⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.  Academic Article
• The Treatment of Heart Failure  Academic Article
• The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor-α and leukotriene B₄ in a novel human whole blood assay  Academic Article
• The gastrointestinal safety of the COX-2 selective inhibitor etoricoxib assessed by both endoscopy and analysis of upper gastrointestinal events  Academic Article
• The ground state of embryonic stem cell self-renewal  Academic Article
• The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain  Academic Article
• The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect  Academic Article
• The role of thromboxane in allergen-induced asthmatic responses  Academic Article
• The top 4 advances in antithrombotic care in the last year  Academic Article
• Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia  Academic Article
• Timing of Angiography and Outcomes in High-Risk Patients With Non–ST-Segment–Elevation Myocardial Infarction Managed Invasively  Academic Article
• Treating Patients With Acute Coronary Syndromes With Aggressive Antiplatelet Therapy (from the Global Registry of Acute Coronary Events)  Academic Article
• Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: Effects of the novel P-glycoprotein inhibitor tariquidar  Academic Article
• Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle  Academic Article
• Vasopeptidase inhibition with omapatrilat in chronic heart failure: acute and long-term hemodynamic and neurohumoral effects  Academic Article
• Venous thromboembolism management: where do novel anticoagulants fit?  Academic Article
• Vorapaxar, Combination Antiplatelet Therapy, and Stroke∗  Academic Article