Pyridines Concept

subject area of

• In vivo and in vitro Validation of Reference Tissue Models for the mGluR₅ Ligand [¹¹C]ABP688  Journal Articles
• A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis  Journal Articles
• A PET study of effects of chronic 3,4‐methylenedioxymethamphetamine (MDMA, “ecstasy”) on serotonin markers in Göttingen minipig brain  Journal Articles
• A Phase II study of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP) and gemcitabine in advanced pancreatic carcinoma. A trial of the Princess Margaret Hospital Phase II consortium  Journal Articles
• A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: The Randomized, phase II study to Evaluate the sAfety and pharmacokinetics of oraL dabIGatran etexilate in patients after heart valve replacemeNt (RE-ALIGN)  Journal Articles
• A comparison of the therapeutic efficacy and tolerability of etoricoxib and diclofenac in patients with osteoarthritis  Journal Articles
• A logical approach to surgical thromboprophylaxis  Journal Articles
• A medium-throughput functional assay of KCNQ2 potassium channels using rubidium efflux and atomic absorption spectrometry  Journal Articles
• A multinomial Phase II study of lonafarnib (SCH 66336) in patients with refractory urothelial cancer☆  Journal Articles
• A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers  Journal Articles
• A phase II study of sorafenib in advanced uterine carcinoma/carcinosarcoma: A trial of the Chicago, PMH, and California Phase II Consortia  Journal Articles
• A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer  Journal Articles
• A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer  Journal Articles
• A phase II trial of sorafenib in first-line metastatic urothelial cancer: a study of the PMH Phase II Consortium  Journal Articles
• A placebo‐controlled study to determine the efficacy of oral disopyramide phosphate for the prophylaxis of ventricular dysrhythmias after acute myocardial infarction.  Journal Articles
• A prospective evaluation of edoxaban compared to warfarin in subjects undergoing cardioversion of atrial fibrillation: The EdoxabaN vs. warfarin in subjectS UndeRgoing cardiovErsion of Atrial Fibrillation (ENSURE-AF) study  Journal Articles
• A randomized phase I clinical and biologic study of two schedules of sorafenib in patients with myelodysplastic syndrome or acute myeloid leukemia: a NCIC (National Cancer Institute of Canada) Clinical Trials Group Study  Journal Articles
• Absorption and antidysrhythmic activity of oral disopyramide phosphate after acute myocardial infarction.  Journal Articles
• Accuracy of a Rapid Diagnostic Test for the Presence of Direct Oral Factor Xa or Thrombin Inhibitors in Urine—A Multicenter Trial  Journal Articles
• Action of mianserin and zimelidine on the norepinephrine receptor coupled adenylate cyclase system in brain: Subsensitivity without reduction in β-adrenergic receptor binding  Journal Articles
• Activated Clotting Time to Guide Heparin Dosing in Non–ST-Segment–Elevation Acute Coronary Syndrome Patients Undergoing Percutaneous Coronary Intervention and Treated With IIb/IIIa Inhibitors  Journal Articles
• Activation of p38 mitogen-activated protein kinase during normal mitosis in the developing retina  Journal Articles
• Activity of cabozantinib after immune checkpoint blockade in metastatic clear-cell renal cell carcinoma  Journal Articles
• Advantages and limitations of the new anticoagulants  Journal Articles
• Andexanet Alfa for Specific Anticoagulation Reversal in Patients with Acute Bleeding during Treatment with Edoxaban  Journal Articles
• Anticoagulation With Otamixaban and Ischemic Events in Non–ST-Segment Elevation Acute Coronary Syndromes  Journal Articles
• Antiplatelet Drugs  Journal Articles
• Antithrombotic Therapy During Percutaneous Coronary Intervention  Journal Articles
• Antithrombotic treatment for peripheral arterial disease  Journal Articles
• Assaying Small-Molecule−Receptor Interactions by Continuous Flow Competitive Displacement Chromatography/Mass Spectrometry  Journal Articles
• Association of cabozantinib dose reductions for toxicity with clinical effectiveness in metastatic renal cell carcinoma: Results from the Canadian Kidney Cancer Information System (CKCis  Conferences
• BAY 43-9006: Early Clinical Data in Patients with Advanced Solid Malignancies  Journal Articles
• Betrixaban (PRT054021): pharmacology, Dose Selection and Clinical Studies  Journal Articles
• Betrixaban compared with warfarin in patients with atrial fibrillation: results of a phase 2, randomized, dose-ranging study (Explore-Xa)  Journal Articles
• Beyond Unfractionated Heparin and Warfarin  Journal Articles
• Biosynthesis of Vitamin B₁ in Yeast. Derivation of the Pyrimidine Unit from Pyridoxine and Histidine. Intermediacy of Urocanic Acid  Journal Articles
• Bivariate evaluation of thromboembolism and bleeding in clinical trials of anticoagulants in patients with atrial fibrillation  Journal Articles
• Bleeding and antidotes in new oral anticoagulants  Journal Articles
• Bleeding with Direct Oral Anticoagulants vs Warfarin: Clinical Experience  Journal Articles
• Bleeding with direct oral anticoagulants vs warfarin: clinical experience  Journal Articles
• Cabozantinib for Progressive Metastatic Castration-resistant Prostate Cancer Following Docetaxel: Combined Analysis of Two Phase 3 Trials  Journal Articles
• Cabozantinib real‐world effectiveness in the first‐through fourth‐line settings for the treatment of metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium  Journal Articles
• Cardioversion of Atrial Fibrillation in ENGAGE AF‐TIMI 48  Journal Articles
• Cerebrovascular Events in 21 105 Patients With Atrial Fibrillation Randomized to Edoxaban Versus Warfarin  Journal Articles
• Cerivastatin versus branded pravastatin in the treatment of primary hypercholesterolemia in primary care practice in Canada: A one-year, open-label, randomized, comparative study of efficacy, safety, and cost-effectiveness  Journal Articles
• Changes in Renal Function in Patients With Atrial Fibrillation  Journal Articles
• Clinical Experience With the New Oral Anticoagulants for Treatment of Venous Thromboembolism  Journal Articles
• Clinical Impact of Bleeding in Cancer-Associated Venous Thromboembolism: Results from the Hokusai VTE Cancer Study  Journal Articles
• Clinical Implications of Reversal Agents for Direct Oral Anticoagulants  Journal Articles
• Clinical evaluation of the efficacy and safety of noberastine, a new H1 antagonist, in seasonal allergic rhinitis: A placebo-controlled, dose-response study  Journal Articles
• Clopidogrel and percutaneous coronary intervention  Journal Articles
• Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non–Small Cell Lung Cancer  Journal Articles
• Comparative Pharmacodynamics and Pharmacokinetics of Oral Direct Thrombin and Factor Xa Inhibitors in Development  Journal Articles
• Comparative effectiveness and safety of the novel oral anticoagulants: do the pivotal clinical trials point to a new paradigm?  Journal Articles
• Comparison of Fatal or Irreversible Events With Extended‐Duration Betrixaban Versus Standard Dose Enoxaparin in Acutely Ill Medical Patients: An APEX Trial Substudy  Journal Articles
• Comparison of the effects of omapatrilat and lisinopril on circulating neurohormones and cytokines in patients with chronic heart failure  Journal Articles
• Complementary studies of the gastrointestinal safety of the cyclo‐oxygenase‐2‐selective inhibitor etoricoxib  Journal Articles
• Compound- and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle  Journal Articles
• Concomitant Use of Antiplatelet Therapy with Dabigatran or Warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Trial  Journal Articles
• Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: A combined α-[11C]MT and [18F]MPPF positron emission tomography study  Conferences
• Cost Effectiveness of EML4-ALK Fusion Testing and First-Line Crizotinib Treatment for Patients With Advanced ALK-Positive Non–Small-Cell Lung Cancer  Journal Articles
• Dabigatran Etexilate  Journal Articles
• Dabigatran Etexilate: Future Directions in Anticoagulant Treatment  Journal Articles
• Dabigatran Versus Warfarin  Journal Articles
• Dabigatran and Warfarin in Vitamin K Antagonist–Naive and –Experienced Cohorts With Atrial Fibrillation  Journal Articles
• Dabigatran compared with warfarin in patients with atrial fibrillation and previous transient ischaemic attack or stroke: a subgroup analysis of the RE-LY trial  Journal Articles
• Dabigatran etexilate for prevention of venous thromboembolism  Journal Articles
• Dabigatran for stroke prevention in atrial fibrillation: the RE-LY trial  Journal Articles
• Dabigatran versus Warfarin for Venous Thromboembolism  Journal Articles
• Dabigatran versus Warfarin in Patients with Atrial Fibrillation  Journal Articles
• Dabigatran versus Warfarin in the Treatment of Acute Venous Thromboembolism  Journal Articles
• Dabigatran: ready for prime time?  Journal Articles
• Design and rationale of the Treatment of Acute Coronary Syndromes with Otamixaban trial: A double-blind triple-dummy 2-stage randomized trial comparing otamixaban to unfractionated heparin and eptifibatide in non–ST-segment elevation acute coronary syndromes with a planned early invasive strategy  Journal Articles
• Determination and visualization of damage to striatal dopaminergic terminals in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism by [18F]-labeled 6-fluoro-L-dopa and positron emission tomography.  Journal Articles
• Determination of pyridine and adenine nucleotide metabolites in Bacillus subtilis cell extract by sweeping borate complexation capillary electrophoresis  Journal Articles
• Development of Potent Forchlorfenuron Analogs and Their Cytotoxic Effect in Cancer Cell Lines.  Journal Articles
• Direct Oral Anticoagulants for Stroke Prevention in Patients With Device-Detected Atrial Fibrillation: A Study-Level Meta-Analysis of the NOAH-AFNET 6 and ARTESiA Trials  Journal Articles
• Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials  Journal Articles
• Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials.  Journal Articles
• Direct oral anticoagulants: evidence and unresolved issues  Journal Articles
• Discovery of an antivirulence compound that reverses β-lactam resistance in MRSA  Journal Articles
• Dose reduction of edoxaban preserves efficacy and safety for the treatment of venous thromboembolism  Journal Articles
• Drug release by pH-responsive molecular tweezers: Atomistic details from molecular modeling  Journal Articles
• ENNOBLE-ATE trial: an open-label, randomised, multi-centre, observational study of edoxaban for children with cardiac diseases at risk of thromboembolism  Journal Articles
• ERG K⁺ currents regulate pacemaker activity in ICC  Journal Articles
• Editorial: healing of refractory reflux oesophagitis – an ongoing unmet clinical need  Journal Articles
• Edoxaban and amiodarone: interactions on multiple levels  Journal Articles
• Edoxaban for the Prevention of Thromboembolism in Patients With Atrial Fibrillation and Bioprosthetic Valves  Journal Articles
• Edoxaban for the Treatment of Cancer-Associated Venous Thromboembolism  Journal Articles
• Edoxaban for the Treatment of Venous Thromboembolism in Patients with Cancer  Journal Articles
• Edoxaban for treatment of venous thromboembolism in patient groups with different types of cancer: Results from the Hokusai VTE Cancer study  Journal Articles
• Edoxaban for treatment of venous thromboembolism in patients with cancer  Journal Articles
• Edoxaban for venous thromboembolism in patients with cancer: results from a non-inferiority subgroup analysis of the Hokusai-VTE randomised, double-blind, double-dummy trial  Journal Articles
• Edoxaban is non-inferior to low-molecular-weight heparin for treating cancer-associated venous thromboembolism  Journal Articles
• Edoxaban versus Warfarin in Patients with Atrial Fibrillation  Journal Articles
• Edoxaban versus enoxaparin–warfarin in patients undergoing cardioversion of atrial fibrillation (ENSURE-AF): a randomised, open-label, phase 3b trial  Journal Articles
• Effect of a new nootropic agent, CGS 5649B, on cognition, function, and behavior in dementia  Journal Articles
• Effect of extended‐duration thromboprophylaxis on venous thromboembolism and major bleeding among acutely ill hospitalized medical patients: a bivariate analysis  Journal Articles
• Effect on Intragastric pH of a PPI with a Prolonged Plasma Half-Life: Comparison between Tenatoprazole and Esomeprazole on the Duration of Acid Suppression in Healthy Male Volunteers  Journal Articles
• Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma  Journal Articles
• Effects of pumaprazole (BY841), a novel reversible proton pump antagonist, and of omeprazole, on intragastric acidity before and after cure of Helicobacter pylori infection  Journal Articles
• Effects of the thromboxane synthetase inhibitor and receptor antagonist terbogrel in patients with primary pulmonary hypertension  Journal Articles
• Efficacy and Safety of Fondaparinux Versus Enoxaparin in Patients With Acute Coronary Syndromes Treated With Glycoprotein IIb/IIIa Inhibitors or Thienopyridines  Journal Articles
• Efficacy and safety of dabigatran compared with warfarin at different levels of international normalised ratio control for stroke prevention in atrial fibrillation: an analysis of the RE-LY trial  Journal Articles
• Efficacy of 5-HT3 Antagonists and 5-HT4 Agonists in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis  Journal Articles
• Emesis induced by inhibitors of type IV cyclic nucleotide phosphodiesterase (PDE IV) in the ferret  Journal Articles
• Endothelium-dependent relaxation factor released by perivascular adipose tissue  Journal Articles
• Epigenetic therapy inhibits metastases by disrupting premetastatic niches  Journal Articles
• Ether-a-go-go-related gene 3 is the main candidate for the E-4031-sensitive potassium current in the pacemaker interstitial cells of Cajal  Journal Articles
• Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2.  Journal Articles
• Evidence and values: requirements for public reimbursement of drugs for rare diseases--a case study in oncology.  Journal Articles
• Evolving use of new oral anticoagulants for treatment of venous thromboembolism  Journal Articles
• Experimental porphyria. I. The experimental porphyrias--a group of distinctive metabolic lesions.  Journal Articles
• Extended Thromboprophylaxis with Betrixaban in Acutely Ill Medical Patients  Journal Articles
• Extended duration of anticoagulation with edoxaban in patients with venous thromboembolism: a post-hoc analysis of the Hokusai-VTE study  Journal Articles
• Extended treatment with edoxaban in cancer patients with venous thromboembolism: A post‐hoc analysis of the Hokusai‐VTE Cancer study  Journal Articles
• Factor Xa and thrombin as targets for new oral anticoagulants  Journal Articles
• Factors affecting antiretroviral pharmacokinetics in HIV-infected women with virologic suppression on combination antiretroviral therapy: a cross-sectional study  Journal Articles
• Fluorescence photometric determination of disopyramide and mono-N-dealkylated disopyramide in plasma after separation by thin-layer chromatography  Journal Articles
• Fostamatinib for the treatment of adult persistent and chronic immune thrombocytopenia: Results of two phase 3, randomized, placebo‐controlled trials  Journal Articles
• Fostamatinib for the treatment of warm antibody autoimmune hemolytic anemia: Phase 2, multicenter, open‐label study  Journal Articles
• Functional subtyping of histamine receptors on the canine proximal colonic mucosa.  Journal Articles
• Gastrointestinal Bleeding With Edoxaban Versus Warfarin  Journal Articles
• Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding  Journal Articles
• Global Gastrointestinal Safety Profile of Etoricoxib and Lumiracoxib  Journal Articles
• Glucose transporter expression in L6 muscle cells: Regulation through insulin- and stress-activated pathways  Journal Articles
• Guidelines for vismodegib in the management of periocular basal cell carcinoma  Journal Articles
• HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants  Journal Articles
• HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity  Journal Articles
• Human airway smooth muscle promotes eosinophil differentiation  Journal Articles
• Hypoxia-Induced Lactate Dehydrogenase Expression and Tumor Angiogenesis  Journal Articles
• Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development  Journal Articles
• Impact of Spontaneous Extracranial Bleeding Events on Health State Utility in Patients with Atrial Fibrillation: Results from the ENGAGE AF‐TIMI 48 Trial  Journal Articles
• Impact of age, comorbidity, and polypharmacy on the efficacy and safety of edoxaban for the treatment of venous thromboembolism: An analysis of the randomized, double-blind Hokusai-VTE trial  Journal Articles
• In vivo hippocampal cornu ammonis 1–3 glutamatergic abnormalities are associated with temporal lobe epilepsy surgery outcomes  Journal Articles
• Incorporating edoxaban into the choice of anticoagulants for atrial fibrillation  Journal Articles
• Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice  Journal Articles
• Inhibition of the colony-stimulating-factor-1 receptor affects the resistance of lung cancer cells to cisplatin  Journal Articles
• International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants  Journal Articles
• Is There a Role for Betrixaban to Prevent Stroke in Medically Ill Patients?  Journal Articles
• Ischaemic and bleeding risk in atrial fibrillation with and without peripheral artery disease and efficacy and safety of full- and half-dose edoxaban vs. warfarin: insights from ENGAGE AF-TIMI 48  Journal Articles
• Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca²⁺ handling and Rho/ROCK signaling  Journal Articles
• KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase  Journal Articles
• Laboratory Monitoring of Non–Vitamin K Antagonist Oral Anticoagulant Use in Patients With Atrial Fibrillation  Journal Articles
• Laboratory measurement of the direct oral anticoagulants  Journal Articles
• Lack of Hormonal Effects of a Single Dose of Nifedipine in Healthy Young Me  Journal Articles
• Lenvatinib Plus Pembrolizumab Versus Standard of Care for Previously Treated Metastatic Colorectal Cancer: Final Analysis of the Randomized, Open-Label, Phase III LEAP-017 Study.  Journal Articles
• Linking Endogenous Factor Xa Activity, a Biologically Relevant Pharmacodynamic Marker, to Edoxaban Plasma Concentrations and Clinical Outcomes in the ENGAGE AF-TIMI 48 Trial  Journal Articles
• Long‐term fostamatinib treatment of adults with immune thrombocytopenia during the phase 3 clinical trial program  Journal Articles
• MN-166 (ibudilast) in Amyotrophic Lateral Sclerosis in a Phase IIb/III Study: COMBAT-ALS Study Design  Journal Articles
• Magnetic resonance venography to assess thrombus resolution with edoxaban monotherapy versus parenteral anticoagulation/warfarin for symptomatic deep vein thrombosis: A multicenter feasibility study  Journal Articles
• Mechanisms of apoptosis induced by purine nucleosides in astrocytes  Journal Articles
• Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation  Journal Articles
• Metabolic Myopathies Discovered During Investigations of Statin Myopathy  Journal Articles
• Metastatic renal cell cancer treatments: An indirect comparison meta-analysis  Journal Articles
• NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank  Journal Articles
• New Anticoagulants for Atrial Fibrillation  Journal Articles
• New Anticoagulants for Treatment of Venous Thromboembolism  Journal Articles
• New Anticoagulants for the Prevention of Thromboembolism  Journal Articles
• New anticoagulants  Conferences
• New aspects on treatment modalities for thromboembolic episodes  Journal Articles
• New oral anticoagulant agents – general features and outcomes in subsets of patients  Journal Articles
• New oral anticoagulants for stroke prevention in atrial fibrillation: impact of study design, double counting and unexpected findings on interpretation of study results and conclusions  Journal Articles
• New oral anticoagulants for thromboprophylaxis in patients having hip or knee arthroplasty  Journal Articles
• New oral anticoagulants in elderly patients  Journal Articles
• New oral anticoagulants: not quite there yet  Journal Articles
• Newly Identified Events in the RE-LY Trial  Journal Articles
• Nitric oxide modulates mechanical strain-induced activation of p38 MAPK in mesangial cells  Journal Articles
• Novel Oral Anticoagulants: A Focused Review for Stroke Physicians  Journal Articles
• Novel Oral Factor Xa and Thrombin Inhibitors in the Management of Thromboembolism  Journal Articles
• Novel oral anticoagulants in gastroenterology practice  Journal Articles
• Optimizing Survival and the Changing Landscape of Targeted Therapy for Intermediate and Advanced Hepatocellular Carcinoma: A Systematic Review  Journal Articles
• Optimizing the safety of treatment for venous thromboembolism in the era of the direct oral anticoagulants  Journal Articles
• Oral Anticoagulant Therapy  Journal Articles
• Oral Direct Factor Xa Inhibitors  Journal Articles
• Oral anticoagulants in coronary heart disease (Section IV) Position paper of the ESC Working Group on Thrombosis – Task Force on Anticoagulants in Heart Disease  Journal Articles
• Oral bisphosphonates  Journal Articles
• Oral direct factor Xa inhibition with edoxaban for thromboprophylaxis after elective total hip replacement  Journal Articles
• Otamixaban in acute coronary syndromes  Journal Articles
• Outcomes With Edoxaban Versus Warfarin in Patients With Previous Cerebrovascular Events  Journal Articles
• Outpatient Management in Patients with Venous Thromboembolism with Edoxaban: A Post Hoc Analysis of the Hokusai-VTE Study  Journal Articles
• Overview of the New Oral Anticoagulants  Journal Articles
• Ozone Inhalation Provokes Glucocorticoid-Dependent and -Independent Effects on Inflammatory and Metabolic Pathways  Journal Articles
• Palbociclib plus letrozole versus placebo plus letrozole in Asian postmenopausal women with oestrogen receptor–positive/human epidermal growth factor receptor 2–negative advanced breast cancer: Primary results from PALOMA-4  Journal Articles
• Peri-operative Adverse Outcomes in Patients with Atrial Fibrillation Taking Warfarin or Edoxaban: Analysis of the ENGAGE AF-TIMI 48 Trial  Journal Articles
• Perioperative Management of Patients Taking Direct Oral Anticoagulants  Journal Articles
• Periprocedural antithrombotic and bridging therapy: recommendations for standardized reporting in patients with arterial indications for chronic oral anticoagulant therapy  Journal Articles
• Pharmacokinetics, safety, activity, and biomarker analysis of palbociclib plus letrozole as first-line treatment for ER+/HER2– advanced breast cancer in Chinese women  Journal Articles
• Phase 1 clinical trial of losmapimod in facioscapulohumeral dystrophy: Safety, tolerability, pharmacokinetics, and target engagement  Journal Articles
• Phase I Targeted Combination Trial of Sorafenib and Erlotinib in Patients with Advanced Solid Tumors  Journal Articles
• Phase I study to determine the safety and pharmacokinetics of the novel Raf kinase and VEGFR inhibitor BAY 43-9006, administered for 28 days on/7 days off in patients with advanced, refractory solid tumors  Journal Articles
• Phase II Trial of Cabozantinib in Recurrent/Metastatic Endometrial Cancer: A Study of the Princess Margaret, Chicago, and California Consortia (NCI9322/PHL86)  Journal Articles
• Phase II Trial of Sorafenib in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Nasopharyngeal Carcinoma  Conferences
• Phase II study of Triapine® in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)  Journal Articles
• Polymer-Grafted Cellulose Nanocrystals as pH-Responsive Reversible Flocculants  Journal Articles
• Pooled safety analysis of BAY 43-9006 (sorafenib) monotherapy in patients with advanced solid tumours: Is rash associated with treatment outcome?  Journal Articles
• Population pharmacokinetic analysis of the oral thrombin inhibitor dabigatran etexilate in patients with non‐valvular atrial fibrillation from the RE‐LY trial  Journal Articles
• Potential of new anticoagulants in patients with cancer  Journal Articles
• Profile of Patients Diagnosed With Acute Venous Thromboembolism in Routine Clinical Practice: The RE-COVERY DVT/PE™ Study  Journal Articles
• Profile of betrixaban and its potential in the prevention and treatment of venous thromboembolism  Journal Articles
• Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate  Journal Articles
• Pyriproxyfen induces intracellular calcium overload and alters antioxidant defenses in Danio rerio testis that may influence ongoing spermatogenesis  Journal Articles
• Randomised, parallel-group, multicentre, multinational phase 2 study comparing edoxaban, an oral factor Xa inhibitor, with warfarin for stroke prevention in patients with atrial fibrillation  Journal Articles
• Randomized, Placebo-Controlled, Phase III Study of First-Line Oxaliplatin-Based Chemotherapy Plus PTK787/ZK 222584, an Oral Vascular Endothelial Growth Factor Receptor Inhibitor, in Patients With Metastatic Colorectal Adenocarcinoma  Journal Articles
• Rationale and design of RE-LY: Randomized evaluation of long-term anticoagulant therapy, warfarin, compared with dabigatran  Journal Articles
• Receptor subtypes mediating spinal cardiovascular effects of angiotensin II in rat using losartan and PD 123319  Journal Articles
• Recurrent venous thromboembolism in patients with pulmonary embolism and right ventricular dysfunction: a post-hoc analysis of the Hokusai-VTE study  Journal Articles
• Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid  Journal Articles
• Reply: regarding the effect of dabigatran plasma concentrations.  Journal Articles
• Reversal of Direct Oral Anticoagulants: Current Status and Future Directions  Journal Articles
• Reversible Cabozantinib-Induced Cardiomyopathy  Journal Articles
• Risk factors for gastrointestinal bleeding in patients with gastrointestinal cancer using edoxaban  Journal Articles
• Rivaroxaban for the prevention and treatment of venous thromboembolism  Journal Articles
• SAPPHIRE: phase III study of sitravatinib plus nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer  Journal Articles
• SREBP inhibition ameliorates renal injury after unilateral ureteral obstruction  Journal Articles
• SREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis  Journal Articles
• Safety and Efficacy of Sorafenib in Elderly Patients Treated in the North American Advanced Renal Cell Carcinoma Sorafenib Expanded Access Program  Journal Articles
• Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America  Journal Articles
• Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Sorafenib: A Review of Four Phase I Trials in Patients with Advanced Refractory Solid Tumors  Journal Articles
• Second‐line treatment of hepatocellular carcinoma after sorafenib: Characterizing treatments used over the past 10 years and real‐world eligibility for cabozantinib, regorafenib, and ramucirumab  Journal Articles
• Selective potentiating effect of RS14203 on a serotoninergic pathway in anesthetized rats  Journal Articles
• Sensitivity of the early-life stages of freshwater mollusks to neonicotinoid and butenolide insecticides  Journal Articles
• Severity of renal impairment in patients with heart failure and atrial fibrillation: implications for non‐vitamin K antagonist oral anticoagulant dose adjustment  Journal Articles
• Sorafenib and Radiation Therapy for the Treatment of Advanced Hepatocellular Carcinoma  Journal Articles
• Sorafenib in Combination With Gemcitabine in Recurrent Epithelial Ovarian Cancer: A Study of the Princess Margaret Hospital Phase II Consortium  Journal Articles
• Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation  Journal Articles
• Stroke prevention in AF: Of Asians and non-Asians  Journal Articles
• Stroke prevention in atrial fibrillation: Closing the gap  Journal Articles
• Stroke prevention in elderly patients with atrial fibrillation: challenges for anticoagulation  Journal Articles
• Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability  Journal Articles
• TGF-β effects on epithelial ion transport and barrier: reduced Cl⁻ secretion blocked by a p38 MAPK inhibitor  Journal Articles
• The CHORUS (Cerivastatin in Heart Outcomes in Renal Disease: Understanding Survival) protocol: A double-blind, placebo-controlled trial in patients with ESRD  Conferences
• The CHORUS (Cerivastatin in Heart Outcomes in Renal Disease: Understanding Survival) protocol: a double-blind, placebo-controlled trial in patients with esrd.  Journal Articles
• The Dissociation into Subunits of Aspartate Aminotransferase from Pig Heart Muscle  Journal Articles
• The Effect of Dabigatran Plasma Concentrations and Patient Characteristics on the Frequency of Ischemic Stroke and Major Bleeding in Atrial Fibrillation Patients  Journal Articles
• The HDAC class I-specific inhibitor entinostat (MS-275) effectively relieves epigenetic silencing of the LAT2 gene mediated by AML1/ETO  Journal Articles
• The Non-Vitamin K Antagonist Oral Anticoagulants in Heart Disease: Section V—Special Situations  Journal Articles
• The Pursuit of Clinically Relevant Measures of Platelet Function After Antiplatelet Drug Therapy⁎⁎Editorials published in the Journal of the American College of Cardiology reflect the views of the authors and do not necessarily represent the views of JACC or the American College of Cardiology.  Journal Articles
• The Treatment of Heart Failure  Journal Articles
• The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor‐α and leukotriene B₄ in a novel human whole blood assay  Journal Articles
• The gastrointestinal safety of the COX-2 selective inhibitor etoricoxib assessed by both endoscopy and analysis of upper gastrointestinal events  Journal Articles
• The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect  Journal Articles
• The role of thromboxane in allergen-induced asthmatic responses  Journal Articles
• The top 4 advances in antithrombotic care in the last year  Journal Articles
• Therapeutic Potential of Spleen Tyrosine Kinase Inhibition for Treating High-Risk Precursor B Cell Acute Lymphoblastic Leukemia  Journal Articles
• Timing of Angiography and Outcomes in High-Risk Patients With Non–ST-Segment–Elevation Myocardial Infarction Managed Invasively  Journal Articles
• Treating Patients With Acute Coronary Syndromes With Aggressive Antiplatelet Therapy (from the Global Registry of Acute Coronary Events)  Journal Articles
• Uptake and binding of the serotonin 5-HT1A antagonist [18F]-MPPF in brain of rats: Effects of the novel P-glycoprotein inhibitor tariquidar  Journal Articles
• Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle  Journal Articles
• Vasopeptidase inhibition with omapatrilat in chronic heart failure: acute and long-term hemodynamic and neurohumoral effects  Journal Articles
• Venous thromboembolism management: where do novel anticoagulants fit?  Journal Articles
• Vorapaxar in the Secondary Prevention of Atherothrombotic Events  Journal Articles
• Vorapaxar, Combination Antiplatelet Therapy, and Stroke∗  Journal Articles