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Stroke and Mortality Risk in Patients With Various...
Journal article

Stroke and Mortality Risk in Patients With Various Patterns of Atrial Fibrillation

Abstract

BACKGROUND: Whether the pattern of atrial fibrillation (AF) modifies the risk/benefit of anticoagulation is controversial. In ENGAGE AF-TIMI 48 trial (Effective Anticoagulation with Factor Xa Next Generation in Atrial Fibrillation-Thrombolysis in Myocardial Infarction 48), the factor Xa inhibitor edoxaban was noninferior to warfarin in preventing stroke or systemic embolic events and significantly reduced bleeding and cardiovascular mortality. …

Authors

Link MS; Giugliano RP; Ruff CT; Scirica BM; Huikuri H; Oto A; Crompton AE; Murphy SA; Lanz H; Mercuri MF

Journal

Circulation Arrhythmia and Electrophysiology, Vol. 10, No. 1,

Publisher

Wolters Kluwer

Publication Date

January 2017

DOI

10.1161/circep.116.004267

ISSN

1941-3149