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Edoxaban for venous thromboembolism in patients...
Journal article

Edoxaban for venous thromboembolism in patients with cancer: results from a non-inferiority subgroup analysis of the Hokusai-VTE randomised, double-blind, double-dummy trial

Abstract

BACKGROUND: Venous thromboembolism occurs commonly in patients with cancer. Direct oral anticoagulants are non-inferior to conventional anticoagulants for the treatment of venous thromboembolism. We hypothesised that edoxaban, a direct oral inhibitor of activated clotting factor Xa, might be more suitable than conventional anticoagulants in the management of cancer-associated venous thromboembolism. The aim of this study was to assess the …

Authors

Raskob GE; van Es N; Segers A; Angchaisuksiri P; Oh D; Boda Z; Lyons RM; Meijer K; Gudz I; Weitz JI

Journal

The Lancet Haematology, Vol. 3, No. 8, pp. e379–e387

Publisher

Elsevier

Publication Date

August 2016

DOI

10.1016/s2352-3026(16)30057-6

ISSN

2352-3026