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Risk factors for gastrointestinal bleeding in...
Journal article

Risk factors for gastrointestinal bleeding in patients with gastrointestinal cancer using edoxaban

Abstract

BACKGROUND: In the Hokusai VTE Cancer study, the risk of major bleeding was 2.9% higher in the edoxaban group compared with the dalteparin group, mainly due to more gastrointestinal bleedings in patients with gastrointestinal cancer. The identification of risk factors for gastrointestinal bleeding may help to guide the use of DOACs in these patients. OBJECTIVES: To evaluate risk factors for gastrointestinal bleeding in patients with …

Authors

Bosch FTM; Mulder FI; Huisman MV; Zwicker JI; Di Nisio M; Carrier M; Segers A; Verhamme P; Middeldorp S; Weitz JI

Journal

Journal of Thrombosis and Haemostasis, Vol. 19, No. 12, pp. 3008–3017

Publisher

Elsevier

Publication Date

December 2021

DOI

10.1111/jth.15516

ISSN

1538-7933