Journal article
Usual On-therapy Ranges of Drug Concentrations in Patients with Atrial Fibrillation Treated with Direct Oral Anticoagulants: A Systematic Review and Meta-analysis
Abstract
Although most patients with atrial fibrillation (AF) receiving a direct oral anticoagulant (DOAC) do not require drug concentration measurements, there are situations where such information could be useful. Existing guidance documents provide usual on-therapy ranges for drug concentrations, but these have important limitations.This is a systematic review and meta-analysis of studies reporting trough and peak levels of DOAC regimens approved for …
Authors
de Vries TAC; Mallick IU; Bhagirath VC; Eikelboom JW; Gomes C; Yi Q; McGrath S; Hirsh J; Chan NC
Journal
Thrombosis and Haemostasis, Vol. 125, No. 06, pp. 563–573
Publisher
Thieme
Publication Date
June 2025
DOI
10.1055/a-2446-1348
ISSN
0340-6245