Direct oral anticoagulants compared with vitamin K antagonists for acute venous thromboembolism: evidence from phase 3 trials Journal Articles uri icon

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  • Key Points DOACs have similar efficacy as VKAs in the treatment of acute symptomatic VTE, but significantly reduce the risk of major bleeding. The efficacy and safety of DOACs in the treatment of acute VTE are consistent in clinically important subgroups.


  • van Es, Nick
  • Coppens, Michiel
  • Schulman, Sam
  • Middeldorp, Saskia
  • Büller, Harry R

publication date

  • September 18, 2014

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