Journal article
Changes in Renal Function in Patients With Atrial Fibrillation An Analysis From the RE-LY Trial
Abstract
BACKGROUND: Vitamin K-dependent factors protect against vascular and renovascular calcification, and vitamin K antagonists may be associated with a decreased glomerular filtration rate (GFR).
OBJECTIVES: This study analyzed changes in GFR during long-term treatment with warfarin or dabigatran etexilate (DE) in patients enrolled in the RE-LY (Randomized Evaluation of Long Term Anticoagulation Therapy) trial.
Authors
Böhm M; Ezekowitz MD; Connolly SJ; Eikelboom JW; Hohnloser SH; Reilly PA; Schumacher H; Brueckmann M; Schirmer SH; Kratz MT
Journal
Journal of the American College of Cardiology, Vol. 65, No. 23, pp. 2481–2493
Publisher
Elsevier
Publication Date
June 2015
DOI
10.1016/j.jacc.2015.03.577
ISSN
0735-1097