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Hypoxia-Induced Lactate Dehydrogenase Expression...
Journal article

Hypoxia-Induced Lactate Dehydrogenase Expression and Tumor Angiogenesis

Abstract

The aim of this review is to discuss the basic science of tumor angiogenesis and recent clinical trial results with angiogenic inhibitors. Colorectal cancer (CRC) continues to be a major cause of all new cancer cases and cancer-related deaths in North America. Although advances in chemotherapy have increased overall survival for patients suffering from metastatic CRC, the survival rate continues to be poor. In order to develop new and more …

Authors

Colgan SM; Mukherjee S; Major P

Journal

Clinical Colorectal Cancer, Vol. 6, No. 6, pp. 442–446

Publisher

Elsevier

Publication Date

March 2007

DOI

10.3816/ccc.2007.n.014

ISSN

1533-0028