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Dabigatran and Warfarin in Vitamin K...
Journal article

Dabigatran and Warfarin in Vitamin K Antagonist–Naive and –Experienced Cohorts With Atrial Fibrillation

Abstract

BACKGROUND: The comparison of anticoagulants dabigatran and warfarin might be most equitable in vitamin K antagonist (VKA)-naive patients. METHODS AND RESULTS: Warfarin and 2 doses of dabigatran-110 mg BID (D110) and 150 mg BID (D150)-were compared in a balanced population of VKA-naive (≤62 days of lifetime VKA exposure, with 33% never prescribed a VKA) and VKA-experienced patients with atrial fibrillation (n=18 113). For VKA-naive and …

Authors

Ezekowitz MD; Wallentin L; Connolly SJ; Parekh A; Chernick MR; Pogue J; Aikens TH; Yang S; Reilly PA; Lip GYH

Journal

Circulation, Vol. 122, No. 22, pp. 2246–2253

Publisher

Wolters Kluwer

Publication Date

November 30, 2010

DOI

10.1161/circulationaha.110.973735

ISSN

0009-7322