DNA Repair Concept

subject area of

• A Novel Aspect of Tumorigenesis—BMI1 Functions in Regulating DNA Damage Response  Journal Articles
• A UV-specific endonucleolytic activity present in human cell extracts  Journal Articles
• A deficiency in the repair of UV and γ-ray damaged DNA in fibroblasts from Cockayne's syndrome  Journal Articles
• A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance  Journal Articles
• A unifying mechanism in neurodegeneration  Journal Articles
• APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress  Journal Articles
• ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice  Journal Articles
• Action of Nitrofurans on E. Coli  Journal Articles
• Adenine Release Is Fast in MutY-catalyzed Hydrolysis of G:A and 8-Oxo-G:A DNA Mismatches  Journal Articles
• An aberration in gamma-ray-enhanced reactivation of irradiated adenovirus in ataxia telangiectasia fibroblasts  Journal Articles
• Analysis of DNA repair in XP–HeLa hybrids; lack of correlation between excision repair of u.v. damage and adenovirus reactivation in an XP(D)-like cell line  Journal Articles
• Breakage of bacterial DNA by nitrofuran derivatives.  Journal Articles
• Bystander Effects in Repair-Deficient Cell Lines  Journal Articles
• CSB Regulates Pathway Choice in Response to DNA Replication Stress Induced by Camptothecin  Journal Articles
• CSB and SMARCAL1 compete for RPA32 at stalled forks and differentially control the fate of stalled forks in BRCA2-deficient cells  Journal Articles
• CSB cooperates with SMARCAL1 to maintain telomere stability in ALT cells  Journal Articles
• CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection  Journal Articles
• Capacity of UV‐lrradiated Human Fibroblasts to Support Adenovirus DNA Synthesis Correlates with Transcription‐Coupled Repair and is Reduced in SV40‐Transformed Cells and Cells Expressing Mutant p53  Journal Articles
• Cell Death Mechanisms Associated with G₂Radiosensitivity in Patients with Prostate Cancer and Benign Prostatic Hyperplasia  Journal Articles
• Che-1 Promotes Tumor Cell Survival by Sustaining Mutant p53 Transcription and Inhibiting DNA Damage Response Activation  Journal Articles
• Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53  Journal Articles
• Cisplatin-modification of DNA repair and ionizing radiation lethality in yeast, Saccharomyces cerevisiae  Journal Articles
• Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells  Journal Articles
• Cockayne syndrome group B protein uses its DNA translocase activity to promote mitotic DNA synthesis  Journal Articles
• Colorectal cancer imaging: A challenge for radiologists  Journal Articles
• Communication of Radiation-Induced Signals in Vivo between DNA Repair Deficient and Proficient Medaka (Oryzias latipes)  Journal Articles
• Comparative studies of host-cell reactivation, cellular capacity and enhanced reactivation of herpes simplex virus in normal, xeroderma pigmentosum and Cockayne syndrome fibroblasts  Journal Articles
• Construction of a recombinant adenovirus containing the den V gene from bacteriophage T4 which can partially restore the DNA repair deficiency in xeroderma pigmentosum fibroblasts  Journal Articles
• Contributions of DNA Damage to Alzheimer’s Disease  Journal Articles
• Crystal Structure of Human XLF: A Twist in Nonhomologous DNA End-Joining  Journal Articles
• Ctp1 protein–DNA filaments promote DNA bridging and DNA double-strand break repair  Journal Articles
• DNA Damage Repair in Huntington's Disease and Other Neurodegenerative Diseases  Journal Articles
• DNA Damage and Biological Expression of Adenovirus: A Comparison of Liquid versus Frozen Conditions of Exposure to γ Rays  Journal Articles
• DNA Lesions That Signal the Induction of Radioresistance and DNA Repair in Yeast  Journal Articles
• DNA Repair Signaling of Huntingtin: The Next Link Between Late-Onset Neurodegenerative Disease and Oxidative DNA Damage  Journal Articles
• DNA Repair in Chlamydomonas reinhardtii Induced by Heat Shock and Gamma Radiation  Journal Articles
• DNA Repair in Huntington’s Disease and Spinocerebellar Ataxias: Somatic Instability and Alternative Hypotheses  Journal Articles
• DNA Strand Breakage and Biological Functions of Human Adenovirus after Gamma Irradiation  Journal Articles
• DNA damage response coregulator ddrR affects many cellular pathways and processes in Acinetobacter baumannii 17978.  Journal Articles
• DNA excision repair in spontaneously diabetic BB wistar rats  Journal Articles
• DNA quaternary structure in the radiation sensitivity of human lymphocytes--a proposed role of copper.  Journal Articles
• DNA repair enzyme expression in chronic lymphocytic leukemia vis-à-vis nitrogen mustard drug resistance  Journal Articles
• Deciphering and simulating models of radiation genotoxicity with CRISPR/Cas9 systems  Journal Articles
• Decreased Repair of Gamma-irradiated Adenovirus inXeroderma PigmentosumFibroblasts  Journal Articles
• Decreased repair of gamma ray damaged DNA in progeria  Journal Articles
• Defective Repair of Ultraviolet- and Gamma-ray-damaged DNA in Fanconi's Anaemia  Journal Articles
• Defective repair of UV-damaged DNA in human tumor and SV40-transformed human cells but not in adenovirus-transformed human cells  Journal Articles
• Deficient base excision repair of oxidative DNA damage induced by methylene blue plus visible light in xeroderma pigmentosum group C fibroblasts  Journal Articles
• Depletion of poly(ADP-ribose) polymerase-1 reduces host cell reactivation of a UV-damaged adenovirus-encoded reporter gene in human dermal fibroblasts  Journal Articles
• Detection of an Involvement of the Human Mismatch Repair Genes hMLH1 and hMSH2 in Nucleotide Excision Repair Is Dependent on UVC Fluence to Cells  Journal Articles
• Differential contribution of XPC, RAD23A, RAD23B and CENTRIN 2 to the UV-response in human cells  Journal Articles
• Differential effects of hypoxia and acidosis on p53 expression, repair of UVC-damaged DNA and viability after UVC in normal and tumor-derived human cells  Journal Articles
• Direct and delayed X‐ray‐induced DNA damage in male mouse germ cells  Journal Articles
• Dose and polymorphic genes xrcc1, xrcc3, gst play a role in the risk of developing erythema in breast cancer patients following single shot partial breast irradiation after conservative surgery  Journal Articles
• ERCC1/XPF Removes the 3′ Overhang from Uncapped Telomeres and Represses Formation of Telomeric DNA-Containing Double Minute Chromosomes  Journal Articles
• ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response.  Journal Articles
• Effect of ERCC-1 overexpression on sensitivity of Chinese hamster ovary cells to DNA damaging agents.  Journal Articles
• Effect of activated nitrofurans on DNA  Journal Articles
• Efficient UV repair requires disengagement of the CSB winged helix domain from the CSB ATPase domain  Journal Articles
• Elevated DNA damage in a mouse model of oxidative stress: impacts of ionizing radiation and a protective dietary supplement  Journal Articles
• Enhanced expression from the human cytomegalovirus immediate-early promoter in a non-replicating adenovirus encoded reporter gene following cellular exposure to chemical DNA damaging agents  Journal Articles
• Enhanced host cell reactivation of a UV-damaged reporter gene in pre-UV-treated cells is delayed in Cockayne syndrome cells  Journal Articles
• Evidence for an involvement of thymidine kinase in the excision repair of ultraviolet‐irradiated herpes simplex virus in human cells  Journal Articles
• Evidence for lack of mitochondrial DNA repair followingcis-dichlorodiammineplatinum treatment  Journal Articles
• Expression of an adenovirus encoded reporter gene and its reactivation following UVC and oxidative damage in cultured fish cells  Journal Articles
• Gamma-Ray-Enhanced Reactivation of Irradiated Adenovirus in Xeroderma Pigmentosum and Cockayne Syndrome Fibroblasts  Journal Articles
• Genetic Polymorphisms and Head and Neck Cancer Outcomes: A Review  Journal Articles
• Genetic interactions between error-prone and error-free postreplication repair pathways in Saccharomyces cerevisiae  Journal Articles
• Heat-shock enhanced reactivation of a UV-damaged reporter gene in human cells involves the transcription coupled DNA repair pathway  Journal Articles
• Host cell reactivation of gene expression for an adenovirus-encoded reporter gene reflects the repair of UVC-induced cyclobutane pyrimidine dimers and methylene blue plus visible light-induced 8-oxoguanine  Journal Articles
• Host cell reactivation of irradiated adenovirus in UV-sensitive Chinese hamster ovary cell mutants  Journal Articles
• Host cell reactivation of sunlamp‐exposed adenovirus in fibroblasts from patients with bloom's syndrome, ataxia telangiectasia, and huntington's disease  Journal Articles
• Host-Cell Reactivation of Irradiated Human Adenovirus  Journal Articles
• Human cells deficient in transcription-coupled repair show prolonged activation of the Jun N-terminal kinase and increased sensitivity following cisplatin treatment  Journal Articles
• Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex  Journal Articles
• Incomplete complementation of the DNA repair defect in cockayne syndrome cells by the denV gene from bacteriophage T4 suggests a deficiency in base excision repair  Journal Articles
• Increased DNA Synthesis and Repair-Enzyme Expression in Lymphocytes From Patients With Chronic Lymphocytic Leukemia Resistant to Nitrogen Mustards  Journal Articles
• Increased expression of p53 enhances transcription-coupled repair and global genomic repair of a UVC-damaged reporter gene in human cells  Journal Articles
• Indirect stimulation of recombination in Escherichia coli K-12: dependence on recJ, uvrA, and uvrD  Journal Articles
• Insights into Intra-Tumoral Heterogeneity: Transcriptional Profiling of Chemoresistant MPM Cell Subpopulations Reveals Involvement of NFkB and DNA Repair Pathways and Contributes a Prognostic Signature  Journal Articles
• Interaction of VP16-213 with the DNA repair antagonist chloroquine  Journal Articles
• Lethal Mutations Attributable to Misrepair of Q-lesions  Journal Articles
• Lethal Mutations, the Survival Curve Shoulder and Split-dose Recovery  Journal Articles
• Lethal mutations and genomic instability  Journal Articles
• Menin Is a Regulator of the Stress Response in Drosophila melanogaster  Journal Articles
• Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways  Journal Articles
• MicroRNA-181a/b: Novel biomarkers to stratify breast cancer patients for PARPi treatment  Journal Articles
• Mitochondrial DNA damage by anticancer agents  Journal Articles
• Modulation of radiation-induced strand break repair by cisplatin in mammalian cells  Journal Articles
• NR1D1 Recruitment to Sites of DNA Damage Inhibits Repair and Is Associated with Chemosensitivity of Breast Cancer  Journal Articles
• Nitrofuran induced mutagenesis and error prone repair in Escherichia coli  Journal Articles
• Nitrogen mustard drug resistant B-cell chronic lymphocytic leukemia as an in vivo model for crosslinking agent resistance  Journal Articles
• Nucleotide excision repair in the human ovarian carcinoma cell line (2008) and its cisplatin-resistant variant (C13*)  Journal Articles
• On the mutagenicity of nitrofurans  Journal Articles
• Partial Complementation of the DNA Repair Defects in Cells from Xeroderma Pigmentosum Groups A, C, D and F but not G by the denV Gene from Bacteriophage T4¶  Journal Articles
• Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis  Journal Articles
• Poly ADP-ribose signaling is dysregulated in Huntington disease.  Journal Articles
• Potential roles for p53 in nucleotide excision repair  Journal Articles
• Pre-UV-Treatment of Cells Results in Enhanced Host Cell Reactivation of a UV Damaged Reporter Gene in CHO-AA8 Chinese Hamster Ovary Cells but Not in Transcription-Coupled Repair Deficient CHO-UV61 Cells  Journal Articles
• RELATIVE REPAIR OF ADENOVIRUS DAMAGED BY SUNLAMP, UV AND γ‐IRRADIATION IN COCKAYNE SYNDROME FIBROBLASTS IS DIFFERENT FROM THAT IN XERODERMA PIGMENTOSUM FIBROBLASTS  Journal Articles
• RETRACTED ARTICLE:Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice  Journal Articles
• RYBP Is a K63-Ubiquitin-Chain-Binding Protein that Inhibits Homologous Recombination Repair  Journal Articles
• Radiation-Induced Teratogenic Effects in Fetal Mice with VaryingTrp53Function: Influence of Prior Heat Stress  Journal Articles
• Radiation-induced bystander effects and the DNA paradigm: An “out of field” perspective  Journal Articles
• Reactive oxygen species generation and expression of DNA repair-related genes after copper exposure in zebrafish (Danio rerio) ZFL cells  Journal Articles
• Recognition and repair of chemically heterogeneous structures at DNA ends  Journal Articles
• Recovery of the radiation survival-curve shoulder in CHO-KI, XRS-5 and revertant XRS-5 populations  Journal Articles
• Reduced capacity to repair irradiated adenovirus in fibroblasts from xeroderma pigmentosum heterozygotes.  Journal Articles
• Reduced host cell reactivation of oxidative DNA damage in human cells deficient in the mismatch repair gene hMSH2  Journal Articles
• Reduced host cell reactivation of oxidatively damaged DNA in ageing human fibroblasts  Journal Articles
• Relationship between clonogenic radiosensitivity, radiation-induced apoptosis and DNA damage/repair in human colon cancer cells  Journal Articles
• Removal of UV photoproducts from an adenovirus-encoded reporter gene following infection of unirradiated and UV-irradiated human fibroblasts.  Journal Articles
• Repair of Radiation-Induced DNA Breaks in Human Adenovirus  Journal Articles
• Role of Cockayne Syndrome Group B Protein in Replication Stress: Implications for Cancer Therapy  Journal Articles
• Role of RAD9-dependent cell-cycle checkpoints in the adaptive response to ionizing radiation in yeast, Saccharomyces cerevisiae  Journal Articles
• Role of the viral and cellular encoded thymidine kinase in the repair of UV-irradiated herpes simplex virus  Journal Articles
• SNPs in DNA repair or oxidative stress genes and late subcutaneous fibrosis in patients following single shot partial breast irradiation  Journal Articles
• Sedimentation Analysis of DNA from Irradiated and Unirradiated L Cells  Journal Articles
• Sensitization of human melanoma cells by tamoxifen to apoptosis induction by pancratistatin, a nongenotoxic natural compound  Journal Articles
• Structural and Functional Interaction between the Human DNA Repair Proteins DNA Ligase IV and XRCC4  Journal Articles
• Studies on DNA Repair in Mammalian Cells: An Endonuclease Which Recognizes Lesions in DNA  Journal Articles
• Targeted radionuclide therapy in combined-modality regimens  Journal Articles
• Tetrameric Ctp1 coordinates DNA binding and DNA bridging in DNA double-strand-break repair  Journal Articles
• The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites  Journal Articles
• The action of 1-nitroso-8-nitroprene in Eachericia coli: DNA adduct formation and mutational consequeces in the absence of necleotide excision-repair  Journal Articles
• The influence of local DNA sequence and DNA repair background on the mutational specificity of 1-nitroso-8-nitropyrene in Escherichia coli: inferences for mutagenic mechanisms.  Journal Articles
• Thymidine kinase deficient human cells have increased UV sensitivity in their capacity to support herpes simplex virus but normal UV sensitivity for colony formation  Journal Articles
• Toward a Detailed Understanding of Base Excision Repair Enzymes:  Transition State and Mechanistic Analyses of N-Glycoside Hydrolysis and N-Glycoside Transfer  Journal Articles
• Transcriptomic Response in the Spleen after Whole-Body Low-Dose X-Ray Irradiation  Journal Articles
• Transition-State Analysis of the DNA Repair Enzyme MutY  Journal Articles
• Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer  Journal Articles
• Tumor protein expression of the DNA repair gene BRCA1 and lethal prostate cancer  Journal Articles
• U.V. Enhanced Reactivation of U.V.- and γ-irradiated Adenovirus in Cockayne Syndrome and Xeroderma Pigmentosum Fibroblasts  Journal Articles
• U.V. Enhanced Reactivation of U.V.- and γ-irradiated Adenovirus in Normal Human Fibroblasts  Journal Articles
• UV-enhanced Expression of a Reporter Gene is Induced at Lower UV Fluences in Transcription-coupled Repair Deficient Compared to Normal Human Fibroblasts, and is Absent in SV40-transformed Counterparts¶  Journal Articles
• UV-enhanced reactivation of a UV-damaged reporter gene suggests transcription-coupled repair is UV-inducible in human cells  Journal Articles
• UV-inducible base excision repair of oxidative damaged DNA in human cells  Journal Articles
• UV‐INDUCED ALKALINE LABILE DNA DAMAGE IN HUMAN ADENOVIRUS AND ITS REPAIR AFTER INFECTION OF HUMAN CELLS  Journal Articles
• Wildtype p53 is required for heat shock and ultraviolet light enhanced repair of a UV-damaged reporter gene  Journal Articles
• XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening  Journal Articles
• Xeroderma pigmentosum d-hela hybrids with low and high ultraviolet sensitivity associated with normal and diminished dna repair ability, respectively  Journal Articles
• Zebrafish CYP1A expression in transgenic Caenorhabditis elegans protects from exposures to benzo[a]pyrene and a complex polycyclic aromatic hydrocarbon mixture  Journal Articles
• γ-ray-enhanced reactivation of UV-irradiated adenovirus in normal human fibroblasts  Journal Articles