Journal article
Action of Nitrofurans on E. Coli Mutation and induction and repair of daughter-strand gaps in DNA
Abstract
The antibacterial and mutagenic potency of 9 nitrofurans in "treat and plate" experiments varied over almost 5 orders of magnitude. The relative toxicities were as follows: FANFT greater than AF2 greater than ANFT greather than furazolidone greater than furagin greater than nitrofurantoin greater than nitrofurazone greater than methylnitrofuroate greater than nitrofuroic acid. In general, mutagenic activity paralleled toxicity. The compounds at …
Authors
Lu C; McCalla DR; Bryant DW
Journal
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Vol. 67, No. 2, pp. 133–144
Publisher
Elsevier
Publication Date
June 1979
DOI
10.1016/0165-1218(79)90124-1
ISSN
0027-5107