Prothrombin
Concept
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Overview
subject area of
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A Control Switch for Prothrombinase Academic Article
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A Protease TAMER: a nucleic acid‐based anticoagulant Academic Article
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A single dose of aprotinin prevents platelet hyporeactivity after coronary artery bypass graft surgery Academic Article
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A549 Lung Epithelial Cells Synthesize Anticoagulant Molecules on the Cell Surface and Matrix and in Conditioned Media Academic Article
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Activated prothrombin complex concentrate for dabigatran-associated bleeding Academic Article
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Activation of factor X and prothrombin in antithrombin-III depleted plasma: The effects of heparin Academic Article
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Age-related changes in factor VII proteolysisin vivo Academic Article
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Age-related differences in heparin response Academic Article
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Altered regulation of in-vivo coagulation in orthopedic patients prior to knee or hip replacement surgery Academic Article
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An Antithrombin III Assay Based on Factor Xa Inhibition Provides a More Reliable Test to Identify Congenital Antithrombin III Deficiency Than an Assay Based on Thrombin Inhibition Academic Article
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An Approach to Assigning In Vitro Potency to Unfractionated and Low Molecular Weight Heparins Based on the Inhibition of Prothrombin Activation and Catalysis of Thrombin Inhibition Academic Article
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An Increased Uptake of Prothrombin, Antithrombin, and Fibrinogen by the Rabbit Balloon-Deendothelialized Aorta Surface In Vivo Is Maintained Until Reendothelialization Is Complete Academic Article
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Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity Academic Article
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Anti-prothrombin antibodies and other acquired antibodies associated with thrombosis in children Academic Article
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Anticoagulant Actions of Tissue Factor Pathway Inhibitor on Tissue-Factor-Dependent Plasma Coagulation Academic Article
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Anticoagulant Mechanisms of Orgaran (Org 10172) and Its Fraction with High Affinity to Antithrombin III (Org 10849) Academic Article
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Are There Patients With Acute Ischemic Stroke and Atrial Fibrillation That Benefit From Low Molecular Weight Heparin? Academic Article
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Beyond Unfractionated Heparin and Warfarin Academic Article
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Bleeding and antidotes in new oral anticoagulants Academic Article
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Catabolism of rabbit prothrombin in rabbits: uptake of prothrombin by the aorta wall before and after a de-endothelializing injury in vivo. Academic Article
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Challenges with heparin-based anticoagulation during cardiopulmonary bypass in children: Impact of low antithrombin activity Academic Article
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Comparative catabolism of prothrombin and antithrombin in normal and alloxan-diabetic rabbits Academic Article
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Comparison of 1 month with 3 months of anticoagulation for a first episode of venous thromboembolism associated with a transient risk factor Academic Article
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Comparison of 5-mg and 10-mg Loading Doses in Initiation of Warfarin Therapy Academic Article
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Comparison of three‐factor and four‐factor prothrombin complex concentrates regarding reversal of the anticoagulant effects of rivaroxaban in healthy volunteers Academic Article
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Conformational Changes in Thrombin When Complexed by Serpins Academic Article
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Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va Academic Article
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Decreased Concentrations of Heparinoids Are Required to Inhibit Thrombin Generation in Plasma from Newborns and Children Compared to Plasma from Adults due to Reduced Thrombin Potential Academic Article
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Decreased Thrombin Activity of Fibrin Clots Prepared in Cord Plasma Compared with Adult Plasma Academic Article
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Differences in prethrombin-1 activation with human or bovine factor Va can be attributed to the heavy chain Academic Article
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Disruption of the kringle 1 domain of prothrombin leads to late onset mortality in zebrafish Academic Article
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Duration of anticoagulant therapy for venous thromboembolism Academic Article
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EFFECT OF SERA ON THROMBIN ACTIVATION RATE CONSTANTS: A ONE-STAGE ASSAY OF THE EXTRINSIC SYSTEM Academic Article
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Effect of Covalent Serpin–Heparinoid Complexes on Plasma Thrombin Generation on Fetal Distal Lung Epithelium Academic Article
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Effect of Heparin Loading During Congenital Heart Operation on Thrombin Generation and Blood Loss Academic Article
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Effect of a novel covalent antithrombin-heparin complex on thrombin generation on fetal distal lung epithelium Academic Article
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Effects of Dermatan Sulfate and Heparin on Inhibition of Thrombus Growth in Vivo Academic Article
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Effects on Thrombin Generation of Single Injections of Hirulog™ in Patients with Calf Vein Thrombosis Academic Article
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EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis Academic Article
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Evidence for Allosteric Linkage between Exosites 1 and 2 of Thrombin Academic Article
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Evolving Treatments for Arterial and Venous Thrombosis Academic Article
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Factor V Leiden and prothrombin gene G20210A mutations in Italian patients with Behçet's disease and deep vein thrombosis Academic Article
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Factors That Predict Risk of Thrombosis in Relatives of Patients With Unprovoked Venous Thromboembolism Academic Article
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Factors that predict thrombosis in relatives of patients with venous thromboembolism Academic Article
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Familial thrombophilia and the prothrombin 20210A mutation Academic Article
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Fibrinolytic properties of lysine-derivatized polyethylene in contact with flowing whole blood (Chandler loop model) Academic Article
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Four-Factor Prothrombin Complex Concentrate for Urgent Reversal of Vitamin K Antagonists in Patients With Major Bleeding Academic Article
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Further Evidence for Two Functional Forms of Prothrombinase Each Specific for Either of the Two Prothrombin Activation Cleavages Academic Article
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HD1, a Thrombin-directed Aptamer, Binds Exosite 1 on Prothrombin with High Affinity and Inhibits Its Activation by Prothrombinase Academic Article
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HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions Academic Article
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HDL and apolipoprotein A-I protect erythrocytes against the generation of procoagulant activity. Academic Article
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Hemostatic System Activation in Patients with Lupus Anticoagulant and Essential Thrombocythemia Academic Article
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Heparan sulfate and dermatan sulfate inhibit the generation of thrombin activity in plasma by complementary pathways. Academic Article
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Heparin and Low Molecular Weight Heparins Inhibit Prothrombinase Formation but not its Activity in Plasma Academic Article
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Heparin sensitivity and resistance in the neonate: An explanation Academic Article
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Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma Academic Article
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Hypercoagulable States Academic Article
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Iatrogenic causes of an ICH Academic Article
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Identification and characterization of a factor Va-binding site on human prothrombin fragment 2 Academic Article
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Identification of a Unique Glomerular Factor X Activator in Murine Lupus Nephritis Academic Article
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Impact of simvastatin on hemostatic and fibrinolytic regulators in Type 2 diabetes mellitus Academic Article
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In the Presence of Phospholipids, Glycosaminoglycans Potentiate Factor Xa-Mediated Protein C Activation by Modulating Factor Xa Activity Academic Article
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In vitro and ex vivo Activities of CY216: Comparison with Other Low Molecular Weight Heparins Academic Article
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Incorporation of Factor Va into Prothrombinase Is Required for Coordinated Cleavage of Prothrombin by Factor Xa Academic Article
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Increased sulphation improves the anticoagulant activities of heparan sulphate and dermatan sulphate Academic Article
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Inherited Thrombophilia in Childhood Arterial Stroke: Data from Lebanon Academic Article
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Inhibition of factor X and factor V activation by dermatan sulfate and a pentasaccharide with high affinity for antithrombin III in human plasma Academic Article
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Inhibition of factor X, factor V and prothrombin activation by the bis(lactobionic acid amide) LW10082 Academic Article
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Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of α-thrombin Academic Article
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Inhibition of thrombin generation by simvastatin and lack of additive effects of aspirin in patients with marked hypercholesterolemia Academic Article
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Interactions of heparin and a covalently-linked antithrombin-heparin complex with components of the fibrinolytic system Academic Article
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International Council for Standardization in Haematology (ICSH) Recommendations for Laboratory Measurement of Direct Oral Anticoagulants Academic Article
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Isolation and characterization of cotiaractivase, a novel low molecular weight prothrombin activator from the venom of Bothrops cotiara Academic Article
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Localization of the Thrombin-binding Domain on Prothrombin Fragment 2 Academic Article
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Measurement of Markers of Activated Coagulation in Antithrombin III Deficient Subjects Academic Article
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Measurement of factor Xa-antithrombin III in plasma: relationship to prothrombin activation in vivo Academic Article
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Mechanism of inhibition of the prothrombinase complex by a covalent antithrombin-heparin complex Academic Article
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Mechanisms for Inhibition of the Generation of Thrombin Activity by Sulfated Polysaccharides Academic Article
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Mechanisms for the Anticoagulant Effects of Synthetic Antithrombins Academic Article
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Mechanisms responsible for the failure of protamine
to inactivate low-molecular-weight heparin Academic Article
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Mesenteric-portal Vein Thrombosis in a Patient with Hyperhomocysteinemia and Heterozygous for 20210A Prothrombin Allele Academic Article
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Metabolism of rabbit plasma-derived factor VII in relation to prothrombin in rabbits Academic Article
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Minimal impact of anticoagulant on in vitro whole blood quality throughout a 35‐day cold‐storage regardless of leukoreduction timing Academic Article
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Modulation of intrinsic prothrombin activation by fibrinogen and fibrin I. Academic Article
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Monitoring and reversal of direct oral anticoagulants Academic Article
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No Association between the 20210 G/A Prothrombin Gene Mutation and Premature Coronary Artery Disease Academic Article
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Optimal reversal of vitamin K antagonists Academic Article
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Periprocedural management of patients receiving a vitamin K antagonist or a direct oral anticoagulant requiring an elective procedure or surgery Academic Article
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Phosphatidylserine externalization and procoagulant activation of erythrocytes induced by
Pseudomonas aeruginosa
virulence factor pyocyanin Academic Article
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Plasma Anticoagulant Mechanisms of Heparin, Heparan Sulfate, and Dermatan Sulfate Academic Article
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Plasma Thrombin Neutralization Assay: Pharmacokinetic Applications Academic Article
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Plasminogen II accumulates five times faster than plasminogen I at the site of a balloon de-endothelializing injury in vivo to the rabbit aorta: Comparison with other hemostatic proteins Academic Article
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Polyphosphate binds with high affinity to exosite II of thrombin Academic Article
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Preclinical differentiation of low molecular weight heparins. Academic Article
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Predictors of the post‐thrombotic syndrome during long‐term treatment of proximal deep vein thrombosis Academic Article
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Probable regulation of factor VIIa–tissue factor and prothrombinase by factor Xa–TFPI and TFPI
in vivo Academic Article
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Prolonged hemorrhagic shock does not impair regeneration of plasma coagulant masses in the rabbit Academic Article
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Prophylactic doses of enoxaparin and heparin inhibit prothrombin activation. Academic Article
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Prophylactically Effective Doses of Enoxaparin and Heparin Inhibit Prothrombin Activation Academic Article
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Proteomic analysis of plasma from Holstein cows testing positive for mycobacterium avium subsp. Paratuberculosis (MAP) Academic Article
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Prothrombin 20210A and familial thrombophilia Academic Article
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Prothrombin complex concentrates reduce blood loss in murine coagulopathy induced by warfarin, but not in that induced by dabigatran etexilate Academic Article
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Prothrombin, alone or in complex concentrates or plasma, reduces bleeding in a mouse model of blood exchange-induced coagulopathy Academic Article
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Prothrombotic Disorders in Infants and Children With Cerebral Thromboembolism Academic Article
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Rationale Behind the Development of Low Molecular Weight Heparin Derivatives Academic Article
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Reactivation of coagulation after stopping infusions of recombinant hirudin and unfractionated heparin in unstable angina and myocardial infarction without ST elevation: results of a randomized trial Academic Article
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Relationship Between Thromboembolic Complications and Intensity of Treatment During Long-Term Prophylaxis with Oral Anticoagulants Following DVT Academic Article
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Reliability of the international normalized ratio for monitoring the induction phase of warfarin: Comparison with the prothrombin time ratio Academic Article
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Review: Laboratory markers quantifying prothrombin activation and actions of thrombin in venous and arterial thrombosis do not accurately assess disease severity or the effectiveness of treatment Academic Article
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Risk of Recurrent Venous Thromboembolism in Patients With Common Thrombophilia Academic Article
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Role of thrombophilic risk factors in children with non-stroke cerebral palsy Academic Article
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SR123781A: A New Once-Daily Synthetic Oligosaccharide Anticoagulant for Thromboprophylaxis After Total Hip Replacement Surgery Academic Article
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Serum-induced platelet procoagulant activity: An assay for the characterization of prothrombotic disorders Academic Article
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Suboptimal effect of a three-factor prothrombin complex concentrate (Profilnine-SD) in correcting supratherapeutic international normalized ratio due to warfarin overdose Academic Article
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Synthesis and turnover of prothrombin during experimental inflammation in rats. Academic Article
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The Antithrombotic Properties of Human Prothrombin Fragment 1.2 in Mice Academic Article
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The Effect of Prothrombotic Blood Abnormalities on Risk of Deep Vein Thrombosis in Users of Hormone Replacement Therapy Academic Article
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The Effects of Hormone Replacement Therapy on Thrombin Generation, Fibrinolysis Inhibition, and Resistance to Activated Protein C Academic Article
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The Procoagulant State of the VX-2 Tumor in Rabbit Lung In Vivo Academic Article
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The activation of coagulation by extracts of mucus: a possible pathway of intravascular coagulation accompanying adenocarcinomas. Academic Article
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The affinity of human, rabbit and bovine thrombins for sepharose-lysine and other conjugates Academic Article
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The blood platelet as a model for regulating blood coagulation on cell surfaces and its consequences. Academic Article
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The direct thrombin inhibitor hirudin Academic Article
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The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces Academic Article
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The hypercoagulable state in cancer patients Academic Article
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The importance of thrombin inhibition for the expression of the anticoagulant activities of heparin, dermatan sulphate, low molecular weight heparin and pentosan polysulphate Academic Article
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The inhibition of thrombin-dependent positive-feedback reactions is critical to the expression of the anticoagulant effect of heparin Academic Article
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The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase Academic Article
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The isolation of prothrombin, factor IX and factor X from human factor IX concentrates Academic Article
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The low molecular weight heparin Enoxaparin inhibits the consumption of factor VII and prothrombin activation in vivo associated with elective knee replacement surgery Academic Article
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The risk of recurrent venous thromboembolism in carriers and non-carriers of the G1691A allele in the coagulation factor V gene and the G20210A allele in the prothrombin gene. DURAC Trial Study Group. Duration of Anticoagulation. Academic Article
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The thrombogenicity of prothrombin complex concentrates: I. The relationship between characteristics and thrombogenicity in rabbits Academic Article
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The thrombogenicity of prothrombin complex concentrates: II. The effect of thrombocytopenia on in vivo thrombogenicity in rabbits Academic Article
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Thrombin Generation and Presence of Thrombin Receptor in Ovarian Follicles1 Academic Article
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Thrombin Generation during Cardiac Surgery: Is Heparin the Ideal Anticoagulant? Academic Article
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Thrombin Generation in Newborn Plasma Is Critically Dependent on the Concentration of Prothrombin Academic Article
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Thrombin Inhibition Is Impaired in Plasma of Sick Neonates Academic Article
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Thrombin Inhibition by Hirudin: How Hirudin Inhibits Thrombin Academic Article
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Thrombin Regulation in Children Differs from Adults in the Absence and Presence of Heparin Academic Article
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Thrombin and Antithrombotics Academic Article
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Thrombin binding to platelets and their activation in plasma Academic Article
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Thromboembolic safety and efficacy of prothrombin complex concentrates in the emergency reversal of warfarin coagulopathy Academic Article
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Thromboepidemiology: Identifying patients with heritable risk for thrombin-mediated thromboembolic events Academic Article
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Thrombophilia and location of venous thromboembolism Academic Article
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Thrombosis in Children Academic Article
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Thrombosis in inherited factor VII deficiency Academic Article
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Towards the genetic basis of cerebral venous thrombosis—the BEAST Consortium: a study protocol: Table 1 Academic Article
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Undercarboxylation of recombinant prothrombin revealed by analysis of γ-carboxyglutamic acid using capillary electrophoresis and laser-induced fluorescence Academic Article
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Unfractionated heparin inhibits thrombin-catalysed amplification reactions of coagulation more efficiently than those catalysed by factor Xa Academic Article
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Uptake of heparin cofactor II and antithrombin into the aorta wall after a deendothelializing injury in vivo: Comparison with the behaviors of prothrombin and fibrinogen Academic Article
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Why Is Factor Xa Not a Better Target Than Factor IIa for Therapeutic Inhibition of Coagulation? Academic Article
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Withdrawal of warfarin after deep vein thrombosis Academic Article
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[Prothromplex in stead of Beriplex P/N as acute antidote against warfarin]. Academic Article
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α2-Macroglobulin Remains as Important as Antithrombin III for Thrombin Regulation in Cord Plasma in the Presence of Endothelial Cell Surfaces Academic Article