Multicenter Studies as Topic Concept

subject area of

• Critical Care Cycling to ImproveLowerExtremity Strength (CYCLE): protocol for an international, multicentre randomised clinical trial of early in-bed cycling for mechanically ventilated patients  Journal Articles
• A Challenging Question Regarding the Use of Topical Corticosteroids for Mycosis Fungoides  Journal Articles
• A Phase II Study of Neoadjuvant Opnurasib KRAS G12C Inhibitor in Patients With Surgically Resectable Non-Small Cell Lung Cancer (CCTG IND.242A): A Substudy of the IND.242 Platform Master Protocol.  Journal Articles
• A Practical Guide to Research: Design, Execution, and Publication  Journal Articles
• A Prediction Model for Sudden Cardiac Death in Patients With Heart Failure and Preserved Ejection Fraction  Conferences
• A community-based clinical trial of Intra-Venous zOledRonic acid once Yearly in comparison to oral bisphosphonates in postmenopausal women with osteoporosis: The IVORY trial  Journal Articles
• A multi-center, pragmatic, effectiveness-implementation (hybrid I) cluster randomized controlled trial to evaluate a child-oriented goal-setting approach in paediatric rehabilitation (the ENGAGE approach): a study protocol  Journal Articles
• A multi-centre, participant-blinded, randomized, 3-year study to compare the efficacy of Virtual Surgical Planning (VSP) to Freehand Surgery (FHS) on bony union and quality of life outcomes for mandibular reconstruction with fibular and scapular free flaps: study protocol for a randomized phase II/III trial.  Journal Articles
• A multinational registry to study the characteristics and outcomes of heart failure patients: The global congestive heart failure (G-CHF) registry  Journal Articles
• A novel lung disease phenotype adjusted for mortality attrition for cystic fibrosis Genetic modifier studies  Journal Articles
• A phase 3 study of ravulizumab to protect patients with chronic kidney disease from cardiac surgery-associated acute kidney injury and major adverse kidney events (ARTEMIS).  Journal Articles
• A prediction model for sudden cardiac death in patients with heart failure and preserved ejection fraction  Journal Articles
• A randomized ablation-based atrial fibrillation rhythm control versus rate control trial in patients with heart failure and high burden atrial fibrillation: The RAFT-AF trial rationale and design  Journal Articles
• A randomized, crossover comparison of ketamine and electroconvulsive therapy for treatment of major depressive episodes: a Canadian biomarker integration network in depression (CAN-BIND) study protocol  Journal Articles
• A three-arm, multicenter, open-label randomized controlled trial of hydroxychloroquine and low-dose prednisone to treat recurrent pregnancy loss in women with undifferentiated connective tissue diseases: protocol for the Immunosuppressant regimens for LIving FEtuses (ILIFE) trial  Journal Articles
• A trial of the Actiderm dermatological patch and topical corticosteroids in the treatment of psoriasis vulgaris. The Actiderm Multi-Center Study Group.  Journal Articles
• A trial platform to assess approved SARS-CoV-2 vaccines in immunocompromised patients: first sub-protocol for a pilot trial comparing the mRNA vaccines Comirnaty® and COVID-19 mRNA Vaccine Moderna®  Journal Articles
• ASymptomatic atrial fibrillation and Stroke Evaluation in pacemaker patients and the atrial fibrillation Reduction atrial pacing Trial (ASSERT)  Journal Articles
• Accounting for center-level effects in multicenter randomized controlled trials  Journal Articles
• Accumulation of Deficits as a Key Risk Factor for Cardiovascular Morbidity and Mortality: A Pooled Analysis of 154 000 Individuals  Journal Articles
• Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials  Journal Articles
• Acupuncture treatment for knee osteoarthritis with sensitive points: protocol for a multicentre randomised controlled trial  Journal Articles
• Acute myelogenous leukemia in adolescents and young adults  Journal Articles
• Adaptive randomised controlled non-inferiority multicentre trial (the Ketodex Trial) on intranasal dexmedetomidine plus ketamine for procedural sedation in children: study protocol  Journal Articles
• Adjudicating Outcomes: Fundamentals  Journal Articles
• Adjudicating ventilator-associated pneumonia in a randomized trial of critically ill patients  Journal Articles
• Adjuvant external beam radiotherapy in the treatment of endometrial cancer (MRC ASTEC and NCIC CTG EN.5 randomised trials): pooled trial results, systematic review, and meta-analysis  Journal Articles
• Agreement in reporting between trial publications and current clinical trial registry in high impact journals: A methodological review  Journal Articles
• An Analysis of the Impact of Timing and Technique on Outcomes after Surgery for Distal Radius Fractures: The Wrist and Radius Injury Surgical Trial Collaborative Study  Journal Articles
• An Innovative Model of Pediatric Emergency Department Mental Health Care: Protocol for a Multicenter Type 1 Effectiveness-Implementation Cluster Randomized Trial  Journal Articles
• An overview of the first 5 years of the ENIGMA obsessive–compulsive disorder working group: The power of worldwide collaboration  Journal Articles
• Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. Reply.  Journal Articles
• Antibiotic prophylaxis for corneal abrasion  Journal Articles
• Anticoagulant therapy after acute myocardial infarction  Journal Articles
• Anxiolysis for laceration repair in children: study protocol for an open-label multicenter adaptive trial (ALICE).  Journal Articles
• Are large clinical trials in orthopaedic trauma justified?  Journal Articles
• Aspirin Versus Low-Molecular-Weight Heparin for Ischemic Stroke in Children: An Unanswered Question  Journal Articles
• Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study  Journal Articles
• Association of cyclooxygenase-2 genetic variant with cardiovascular disease  Journal Articles
• Association of mitral annular calcification and aortic valve morphology: a substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study  Journal Articles
• Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE) randomised clinical trial: study protocol  Journal Articles
• Becoming and staying physically active in adolescents with cerebral palsy: protocol of a qualitative study of facilitators and barriers to physical activity  Journal Articles
• Burden of Proof for Tolvaptan in ADPKD  Journal Articles
• Burden of respiratory syncytial virus hospitalisation among infants born at 32–35 weeks' gestational age in the Northern Hemisphere: pooled analysis of seven studies  Journal Articles
• CANadian Network and Centre for Trials INternationally (CANNeCTIN): A national network for Canadian-led trials in cardiovascular diseases and diabetes mellitus  Journal Articles
• COMET (Composite Outcomes of Mesh vs suture Techniques for prolapse repair)- Protocol for a single blind randomized controlled multicenter trial testing surgical innovation in female pelvic surgery.  Journal Articles
• Calcineurin Inhibitor in NEuRoloGically deceased donors to decrease kidney delayed graft function study: study protocol of the CINERGY Pilot randomised controlled trial  Journal Articles
• Can orthopedic trials change practice?  Journal Articles
• Canadian Anaphylaxis Network-Predicting Recurrence after Emergency Presentation for Allergic REaction (CAN-PREPARE): a prospective, cohort study protocol  Journal Articles
• Candidemia in patients with diabetes mellitus: epidemiology and predictors of mortality  Journal Articles
• Cannabinoids and an anti-inflammatory diet for the treatment of neuropathic pain after spinal cord injury (The CATNP Study): study protocol for a randomized controlled trial  Journal Articles
• Care and outcomes of Canadian children hospitalised with periorbital and orbital cellulitis: protocol for a multicentre, retrospective cohort study  Journal Articles
• Carotid plaque formation and its evaluation with angiography, ultrasound, and MR angiography  Journal Articles
• Cefoperazone compared with ampicillin plus tobramycin for severe biliary tract infections  Journal Articles
• Central statistical monitoring: Detecting fraud in clinical trials  Journal Articles
• Challenges in the conduct of large simple trials of important generic questions in resource-poor settings: The CREATE and ECLA trial program evaluating GIK (glucose, insulin and potassium) and low-molecular-weight heparin in acute myocardial infarction  Journal Articles
• Challenges to complete and useful data sharing  Journal Articles
• Chinese herbal medicine Shenzhuo Formula treatment in patients with macroalbuminuria secondary to diabetic kidney disease: study protocol for a randomized controlled trial  Journal Articles
• Choices of Methodology in Pharmacoeconomic Studies  Journal Articles
• Choisir un questionnaire de qualité de vie  Journal Articles
• Classification and appraisal of the level of clinical evidence of publications from the Canadian Association of Pediatric Surgeons for the past 10 years  Journal Articles
• Clinical Research: From Case Reports to International Multicenter Clinical Trials  Journal Articles
• Clinical trial update: National Cancer Institute of Canada  Journal Articles
• Coached, Coordinated, Enhanced Neonatal Transition (CCENT): protocol for a multicentre pragmatic randomised controlled trial of transition-to-home support for parents of high-risk infants  Journal Articles
• Cognitive Behavioural Therapy to Optimize Post-Operative Fracture Recovery (COPE): protocol for a randomized controlled trial  Journal Articles
• Cognitive Outcomes after DEXmedetomidine sedation in cardiac surgery: CODEX randomised controlled trial protocol  Journal Articles
• Cognitive impairment and risk of cardiovascular events and mortality  Journal Articles
• Collaborative multicenter trials in Latin America: challenges and opportunities in orthopedic and trauma surgery  Journal Articles
• Combination chemotherapy confers modest survival advantage in patients with advanced non-small cell lung cancer: report of a Canadian multicenter randomized trial.  Journal Articles
• Combination of first-line chemotherapy with Kanglaite injections versus first-line chemotherapy alone for advanced non-small-cell lung cancer: study protocol for an investigator-initiated, multicenter, open-label, randomized controlled trial  Journal Articles
• Combined Analysis of Asthma Safety Trials of Long-Acting β₂-Agonists  Journal Articles
• Comment on ‘A multicentre randomized controlled trial of expectant management versus IVF in women with Fallopian tube patency’  Journal Articles
• Comparative Therapeutic Studies with Tilavist  Journal Articles
• Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: A simulation study  Journal Articles
• Comparison of 12 Risk Stratification Schemes to Predict Stroke in Patients With Nonvalvular Atrial Fibrillation  Journal Articles
• Comparisons of cause of death verification methods and costs in the lipid research clinics program mortality follow-up study  Journal Articles
• Complex care for kids Ontario: protocol for a mixed-methods randomised controlled trial of a population-level care coordination initiative for children with medical complexity  Journal Articles
• Conducting economic evaluations alongside multinational clinical trials: Toward a research consensus  Journal Articles
• Constructing common cohorts from trials with overlapping eligibility criteria: implications for comparing effect sizes between trials  Journal Articles
• Construction of a FRAX® model for the assessment of fracture probability in Canada and implications for treatment  Journal Articles
• Contrasting evidence to reimbursement reality for off-label use (OLU) of drug treatments in cancer care: rationale and design of the CEIT-OLU project  Journal Articles
• Convalescent plasma for adults with acute COVID-19 respiratory illness (CONCOR-1): study protocol for an international, multicentre, randomized, open-label trial  Journal Articles
• Coordination of international multicenter studies: governance and administrative structure  Journal Articles
• Coronary stenting in diabetic patients: Results from the ROSETTA registry  Journal Articles
• Cost Implications of the Use of Ramipril in High-Risk Patients Based on the Heart Outcomes Prevention Evaluation (HOPE) Study  Journal Articles
• Cost‐effectiveness analysis of a multinational RCT with a binary measure of effectiveness and an interacting covariate  Journal Articles
• Country specific cost comparisons from multinational clinical trials using empirical Bayesian shrinkage estimation: the Canadian ASSENT-3 economic analysis  Journal Articles
• Cuff leak test and airway obstruction in mechanically ventilated ICU patients (COSMIC): a pilot feasibility randomized controlled trial protocol.  Journal Articles
• Cytoreductive nephrectomy in metastatic renal cell carcinoma: the evolving role of surgery in the era of molecular targeted therapy  Journal Articles
• DIVERT-Collaboration Action Research and Evaluation (CARE) Trial Protocol: a multiprovincial pragmatic cluster randomised trial of cardiorespiratory management in home care  Journal Articles
• Design and Analytic Considerations in Determining the Cost-Effectiveness of Early Intervention in Asthma from a Multinational Clinical Trial  Journal Articles
• Design and baseline characteristics of participants in the Researching cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) trial on the cardiovascular effects of dulaglutide  Journal Articles
• Design and rationale of the CLEAR SYNERGY (OASIS 9) trial: A 2x2 factorial randomized controlled trial of colchicine versus placebo and spironolactone vs placebo in patients with myocardial infarction  Journal Articles
• Design and rationale of the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation (COURAGE) trial  Journal Articles
• Design of the INPULSIS™ trials: Two phase 3 trials of nintedanib in patients with idiopathic pulmonary fibrosis  Journal Articles
• Detecting irregularities in randomized controlled trials using machine learning.  Journal Articles
• Development of a clinical prediction model for the postthrombotic syndrome in a prospective cohort of patients with proximal deep vein thrombosis  Journal Articles
• Diabetes mellitus, a predictor of morbidity and mortality in the studies of left ventricular dysfunction (SOLVD) trials and registry  Journal Articles
• Diarrhoea: interventions, consequences and epidemiology in the intensive care unit (DICE-ICU): a protocol for a prospective multicentre cohort study  Journal Articles
• Diffuse malignant mesothelioma of the pleura in Ontario and Quebec: a retrospective study of 332 patients.  Journal Articles
• Doppler identified venous congestion in septic shock: protocol for an international, multi-centre prospective cohort study (Andromeda-VEXUS)  Journal Articles
• Economic Analysis: Randomized Placebo-Controlled Clinical Trial of Erlotinib in Advanced Non-Small Cell Lung Cancer  Journal Articles
• Economic Evaluation of Rivastigmine in Patients with Parkinson??s Disease Dementia  Journal Articles
• Economic evaluation alongside the Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (E-PROSPECT): study protocol  Journal Articles
• Effect of Angiotensin-Converting Enzyme Inhibitors in Left Ventricular Dysfunction  Journal Articles
• Effect of acute angiotensin converting enzyme inhibition on left ventricular filling in patients with congestive heart failure. Relation to right ventricular volumes.  Journal Articles
• Effect of age on mortality, hospitalizations and response to digoxin in patients with heart failure: the DIG study  Journal Articles
• Effectiveness and safety of Chinese herbal medicine xuanbi antong granules for the treatment of borderline coronary lesions: study protocol for a randomised, double-blinded, placebo-controlled, multicentre clinical trial  Journal Articles
• Effectiveness of Dorzolamide–Timolol (COSOPT) in Patients Who Were Treatment Naive for Open-Angle Glaucoma or Ocular Hypertension: The COSOPT First-Line Study  Journal Articles
• Effects of accelerated versus standard care surgery on the risk of acute kidney injury in patients with a hip fracture: a substudy protocol of the hip fracture Accelerated surgical TreaTment And Care tracK (HIP ATTACK) international randomised controlled trial  Journal Articles
• Effects of exercise interventions on cardiovascular health in individuals with chronic, motor complete spinal cord injury: protocol for a randomised controlled trial [Cardiovascular Health/Outcomes: Improvements Created by Exercise and education in SCI (CHOICES) Study]  Journal Articles
• Effects on Mortality and Major Bleeding of Radial Versus Femoral Artery Access for Coronary Angiography or Percutaneous Coronary Intervention: Meta-Analysis of Individual Patient Data From 7 Multicenter Randomized Clinical Trials  Journal Articles
• Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis  Journal Articles
• El uso de metodología estadística actualizada en la investigación biomédica: el ejemplo de metodología para análisis interino en ensayos clínicos  Journal Articles
• Emergence of the Primary Pediatric Stroke Center  Journal Articles
• Emphysema sufferers breathe easier.  Journal Articles
• Endovascular therapy for advanced post-thrombotic syndrome: Proceedings from a multidisciplinary consensus panel  Journal Articles
• Enrolment patterns in a randomized controlled trial of probiotics in critically ill patients: a retrospective analysis of the PROSPECT trial.  Journal Articles
• Evaluating probiotics for the prevention of ventilator-associated pneumonia: a randomised placebo-controlled multicentre trial protocol and statistical analysis plan for PROSPECT  Journal Articles
• Evaluating the effectiveness of rosuvastatin in preventing the progression of diastolic dysfunction in aortic stenosis: A substudy of the aortic stenosis progression observation measuring effects of rosuvastatin (ASTRONOMER) study  Journal Articles
• Evaluation of outcome and cost-effectiveness using an FDG PET-guided approach to management of patients with coronary disease and severe left ventricular dysfunction (PARR-2): rationale, design, and methods  Journal Articles
• Event adjudication and data monitoring in an intensive care unit observational study of thromboprophylaxis  Journal Articles
• Exploring the experiences and perspectives of substitute decision-makers involved in decisions about deceased organ donation: a qualitative study protocol  Journal Articles
• Factors affecting blood pressure responses to diet: The vanguard study  Journal Articles
• Feasibility study protocol of a pragmatic, randomised controlled pilot trial: membrane sweeping to prevent post-term pregnancy—the MILO Study  Journal Articles
• Femoroacetabular Impingement Randomised controlled Trial (FIRST) - a multi-centre randomized controlled trial comparing arthroscopic lavage and arthroscopic osteochondroplasty on patient important outcomes and quality of life in the treatment of young adult (18–50 years) femoroacetabular impingement: a statistical analysis plan  Journal Articles
• Financial Concerns Prompt Sponsoring Pharmaceutical Company to Halt International Phase I Studies  Journal Articles
• Fondaparinux vs Enoxaparin for the Prevention of Venous Thromboembolism in Major Orthopedic Surgery<subtitle>A Meta-analysis of 4 Randomized Double-blind Studies</subtitle>  Journal Articles
• Fracture prediction and calibration of a Canadian FRAX® tool: a population-based report from CaMos  Journal Articles
• Frequency of Screening and SBT Technique Trial - North American Weaning Collaboration (FAST-NAWC): a protocol for a multicenter, factorial randomized trial  Journal Articles
• Frequency of screening and SBT Technique Trial—North American Weaning Collaboration (FAST-NAWC): an update to the protocol and statistical analysis plan  Journal Articles
• Gemifloxacin versus Amoxicillin/Clavulanate in the Treatment of Acute Exacerbations of Chronic Bronchitis  Journal Articles
• Generalizability of results from the recent FDA-guided cardiovascular outcomes trials to a representative population with Type 2 Diabetes attending primary care clinics  Journal Articles
• Globally optimal trial design for local decision making  Journal Articles
• Haemoglobin transfusion threshold in traumatic brain injury optimisation (HEMOTION): a multicentre, randomised, clinical trial protocol  Journal Articles
• Haemorrhagic and Thromboembolic Complications versus Intensity of Treatment of Venous Thromboembolism with Oral Anticoagulants  Journal Articles
• Haemorrhagic and thromboembolic complications versus intensity of treatment of venous thromboembolism with oral anticoagulants.  Journal Articles
• Health-Related Quality of Life at Age 10 Years in Very Low-Birth-WeightChildren With and Without Threshold Retinopathy of Prematurity  Journal Articles
• Heart Failure Risk Assessment Using Biomarkers in Patients With Atrial Fibrillation: Analysis From COMBINE-AF.  Journal Articles
• Hemostatic efficacy of pathogen-inactivated vs untreated platelets: a randomized controlled trial  Journal Articles
• High continuous positive airway pressures versus non-invasive positive pressure ventilation in preterm neonates: protocol for a multicentre pilot randomised controlled trial  Journal Articles
• High-Sensitivity Cardiac Troponin—Optimizing the Diagnosis of Acute Myocardial Infarction/Injury in Women (CODE-MI): Rationale and design for a multicenter, stepped-wedge, cluster-randomized trial  Journal Articles
• Hospital Selection for Unit Cost Estimates in Multicentre Economic Evaluations  Journal Articles
• How Did We Get Here?: A Historical Review and Critical Analysis of Anticoagulation Therapy Following Mechanical Valve Replacement  Journal Articles
• Human Papillomavirus Triage of Atypical Squamous Cells of Undetermined Significance: Cost-Effective, But At What Cost?  Journal Articles
• Immunosuppressive activity in human in vitro fertilization (IVF) culture supernatants and prediction of the outcome of embryo transfer: A multicenter trial  Journal Articles
• Impact of Diabetes on Long-Term Prognosis in Patients With Unstable Angina and Non–Q-Wave Myocardial Infarction  Journal Articles
• Impact of Frailty on the Benefits of Dual Pathway Inhibition for the Secondary Prevention of Cardiovascular Events in the COMPASS Randomised Trial  Journal Articles
• Impact of Virtual Care With Remote Automated Monitoring on the Rate of Acute Hospital Care Post Discharge and Index Length of Hospital Stay: Protocol for the Post Discharge After Surgery Virtual Care With Remote Automated Monitoring Technology 3 (PVC-RAM-3) Trial.  Journal Articles
• Implementation of Timeline Reforms Speeds Initiation of National Cancer Institute-Sponsored Trials  Journal Articles
• Implementing physical activity for individuals with cancer during treatment: protocol for the IMPACT implementation-effectiveness trial.  Journal Articles
• Importance of infarct topography in determination of stroke mechanism and recurrence risk: a post-hoc analysis of the dabigatran acute treatment of stroke trial.  Journal Articles
• Incidence of venous thromboembolism in patients undergoing thoracotomy for lung cancer  Journal Articles
• Incorporating Utility-Based Quality-of-Life Assessment Measures in Clinical Trials  Journal Articles
• Increased cardiovascular risk after pre‐eclampsia in women with dysglycaemia  Journal Articles
• Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients  Journal Articles
• Individual Participant Data Meta-Analysis of LR-5 in LI-RADS Version 2018 versus Revised LI-RADS for Hepatocellular Carcinoma Diagnosis  Journal Articles
• Individual Patient Data from the Pivotal Randomized Controlled Trials of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation (COMBINE AF): Design and Rationale  Journal Articles
• Insights into the role of thrombin in the pathogenesis of recurrent ischaemia after acute coronary syndrome  Journal Articles
• Inter-institutional data-driven education research: consensus values, principles, and recommendations to guide the ethical sharing of administrative education data in the Canadian medical education research context  Journal Articles
• International longitudinal registry of patients with atrial fibrillation at risk of stroke: Global Anticoagulant Registry in the FIELD (GARFIELD)  Journal Articles
• International point prevalence study of Intensive Care Unit transfusion practices—Pilot study in the Netherlands  Journal Articles
• Interpreting Geographic Variations in Results of Randomized, Controlled Trials  Journal Articles
• Intravenous acetaminophen for postoperative pain in the neonatal intensive care unit: A protocol for a pilot randomized controlled trial (IVA POP)  Journal Articles
• Introducing an innovative model of acute paediatric mental health and addictions care to paediatric emergency departments: a protocol for a multicentre prospective cohort study  Journal Articles
• Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial  Journal Articles
• Iron overload in myelodysplastic syndromes: Evidence based guidelines from the Canadian consortium on MDS  Journal Articles
• Launch of the Canadian Neurosurgery Research Collaborative  Journal Articles
• Lessons from a multicenter, international, large sample size analysis of patients with obsessive–compulsive disorders: an overview of the ICOCS Snapshot studies  Journal Articles
• Lessons learned from enrollment in the BEST study—A multicenter, randomized trial of group psychosocial support in metastatic breast cancer  Journal Articles
• Lessons learned from the DIG trial  Journal Articles
• Limiting loss to follow-up in a multicenter randomized trial in orthopedic surgery  Journal Articles
• Long-term outcomes of total elbow arthroplasty for distal humeral fracture: results from a prior randomized clinical trial  Journal Articles
• Longitudinal Youth in Transition Study (LYiTS): protocol for a multicentre prospective cohort study of youth transitioning out of child and adolescent mental health services at age 18  Journal Articles
• Low Adherence to Recommended Guidelines for Open Fracture Antibiotic Prophylaxis  Journal Articles
• Low-Molecular-Weight Heparin or Oral Anticoagulation for Secondary Prevention of Deep Vein Thrombosis in Cancer Patients  Journal Articles
• Low-dose cyclosporin versus placebo in patients with rheumatoid arthritis  Journal Articles
• MUFFIN-PTS trial, Micronized Purified Flavonoid Fraction for the Treatment of Post-Thrombotic Syndrome: protocol of a randomised controlled trial  Journal Articles
• Melatonin Antioxidative Defense: Therapeutical Implications for Aging and Neurodegenerative Processes  Journal Articles
• Monitoring and auditing protocol adherence, data integrity and ethical conduct of a randomized clinical trial: A case study  Journal Articles
• Moving forward through consensus: protocol for a modified Delphi approach to determine the top research priorities in the field of orthopaedic oncology  Journal Articles
• Multicenter Collaboration in Observational Research: Improving Generalizability and Efficiency  Journal Articles
• Multicenter Radial Artery Patency Study (RAPS)  Journal Articles
• Multicenter Study of General Anesthesia. I. Design and Patient Demography  Journal Articles
• Multicenter Study of General Anesthesia. II. Results  Journal Articles
• Multicenter clinical research in adult critical care  Journal Articles
• Multicentre randomised controlled trial comparing Bankart repair with remplissage and Latarjet procedure in shoulder instability with subcritical bone loss (STABLE): study protocol.  Journal Articles
• Multicentre, randomised clinical trial of paediatric concussion assessment of rest and exertion (PedCARE): a study to determine when to resume physical activities following concussion in children  Journal Articles
• Multicentre, single-blind randomised controlled trial comparing MyndMove neuromodulation therapy with conventional therapy in traumatic spinal cord injury: a protocol study  Journal Articles
• National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease: VI. Design of Clinical Trials Working Group Report  Journal Articles
• Neoadjuvant chemotherapy versus debulking surgery in advanced tubo-ovarian cancers: pooled analysis of individual patient data from the EORTC 55971 and CHORUS trials  Journal Articles
• Neurologic Physiology after Removal of Therapy (NeuPaRT) study: study protocol of a multicentre, prospective, observational, pilot feasibility study of neurophysiology after withdrawal of life-sustaining measures  Journal Articles
• New Strategies for the Optimal Use of Platelet Transfusions  Journal Articles
• Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation commenced early during critical illness  Journal Articles
• Once-Daily Therapy with Ceftriaxone Compared with Daily Multiple-Dose Therapy with Cefotaxime for Serious Bacterial Infections: A Randomized, Double-Blind Study  Journal Articles
• Ontario Cancer Research Ethics Board: Lessons Learned From Developing a Multicenter Regional Institutional Review Board  Journal Articles
• Opportunities for enhancing the care of older patients with ST-elevation myocardial infarction presenting for primary percutaneous coronary intervention: Rationale and design of the SAFE-STEMI for Seniors trial  Journal Articles
• Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery  Journal Articles
• Our Choice: study protocol for a randomized controlled trial for optimal implementation of psoriasis treatment by the integration of Chinese and western medicine  Journal Articles
• Outcome assessment for clinical trials: How many adjudicators do we need?  Journal Articles
• Overview of the DIG trial  Journal Articles
• Overview of the Randomized Trials of Radiotherapy in Ductal Carcinoma In Situ of the Breast  Journal Articles
• POP-Brazil study protocol: a nationwide cross-sectional evaluation of the prevalence and genotype distribution of human papillomavirus (HPV) in Brazil  Journal Articles
• PREVENTion of CLots in Orthopaedic Trauma (PREVENT CLOT): a randomised pragmatic trial protocol comparing aspirin versus low-molecular-weight heparin for blood clot prevention in orthopaedic trauma patients  Journal Articles
• PROphylaxis for ThromboEmbolism in Critical Care Trial protocol and analysis plan  Journal Articles
• Participating in Multicenter Randomized Controlled Trials: What’s the Relative Value?  Journal Articles
• Patient and caregiver involvement in a multicentre clustered hemodialysis trial  Journal Articles
• Patient engagement in research related to accelerated surgical care and treatment for hip fracture  Journal Articles
• Patterns of Medication Use in Patients With Heart Failure  Journal Articles
• Peri-Operative Eltrombopag or Immune Globulin for Patients with Immune Thrombocytopaenia (The Bridging ITP Trial): Methods and Rationale  Journal Articles
• Perioperative Troponin Screening Identifies Patients at Higher Risk for Major Cardiovascular Events in Noncardiac Surgery  Journal Articles
• Personalized dosing of nicotine replacement therapy versus standard dosing for the treatment of individuals with tobacco dependence: study protocol for a randomized placebo-controlled trial  Journal Articles
• Perturbation training to promote safe independent mobility post-stroke: study protocol for a randomized controlled trial  Journal Articles
• Pharmacological Actions of Sulodexide  Journal Articles
• Photobiomodulation as part of multimodal analgesia to improve pain relief and wound healing after elective caesarean section: A protocol for randomized controlled trial.  Journal Articles
• Physical activity in patients with stable coronary heart disease: an international perspective  Journal Articles
• Plasma Matrix Metalloproteinase-9 Level Is Correlated With Left Ventricular Volumes and Ejection Fraction in Patients With Heart Failure  Journal Articles
• Plasma exchange in Canada. The Canadian Apheresis Study Group.  Journal Articles
• Platelet function testing: does a randomized controlled trial settle the debate?  Journal Articles
• Pooling Birth Cohorts in Allergy and Asthma: European Union-Funded Initiatives – A MeDALL, CHICOS, ENRIECO, and GA2LEN Joint Paper  Journal Articles
• Positive Effect of Etidronate Therapy Is Maintained After Drug Is Terminated in Patients Using Corticosteroids  Journal Articles
• Practical Understanding of Mean Percent Psoriasis Area and Severity Index Reduction for Biologics  Journal Articles
• Predicting Malignancy Risk of Screen-Detected Lung Nodules–Mean Diameter or Volume  Journal Articles
• Predictors of clinical outcome in patients with heparin-induced thrombocytopenia treated with direct thrombin inhibition  Journal Articles
• Predictors of treatment response in patients with non‐erosive reflux disease  Journal Articles
• Preoperative estimated glomerular filtration rate to predict cardiac events in major noncardiac surgery: a secondary analysis of two large international studies.  Journal Articles
• Present criteria for prophylactic ICD implantation: Insights from the EU-CERT-ICD (Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope) project  Journal Articles
• Prevention of Infections in Cardiac Surgery study (PICS): study protocol for a pragmatic cluster-randomized factorial crossover pilot trial  Journal Articles
• Prevention of persistent pain with lidocaine infusions in breast cancer surgery (PLAN): study protocol for a multicenter randomized controlled trial  Journal Articles
• Prevention of venous thromboembolism in medical patients with enoxaparin  Journal Articles
• Primary care-based integrated disease management for heart failure: a study protocol for a cluster randomised controlled trial  Journal Articles
• Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility. Con: the hazards of stopping for futility.  Journal Articles
• Pro/con clinical debate: It is acceptable to stop large multicentre randomized controlled trials at interim analysis for futility. Pro: Futility stopping can speed up the development of effective treatments.  Journal Articles
• Pro: “Anti-platelet therapy is an alternative to oral anticoagulation for atrial fibrillation”  Journal Articles
• Prognostic accuracy of qSOFA score, SIRS criteria, and EWSs for in-hospital mortality among adult patients presenting with suspected infection to the emergency department (PASSEM) Multicenter prospective external validation cohort study protocol  Journal Articles
• Prognostic factors and outcomes of COVID-19 cases in Ethiopia: multi-center cohort study protocol  Journal Articles
• Progression to chronic atrial fibrillation after pacing: the Canadian Trial of Physiologic Pacing  Journal Articles
• Project management lessons learned from the multicentre CYCLE pilot randomized controlled trial  Journal Articles
• Propensity score matched comparison of subcutaneous and transvenous implantable cardioverter-defibrillator therapy in the SIMPLE and EFFORTLESS studies  Journal Articles
• Prospective Surveillance for Primary Bloodstream Infections Occurring in Canadian Hemodialysis Units  Journal Articles
• Prospective, randomized, controlled, double-blind, multi-center, multinational study on the safety and efficacy of 6% Hydroxyethyl starch (HES) sOlution versus an Electrolyte solutioN In patients undergoing eleCtive abdominal Surgery: study protocol for the PHOENICS study  Journal Articles
• Protocol for a multicenter prospective cohort study evaluating arthroscopic and non-surgical treatment for microinstability of the hip joint  Journal Articles
• Protocol for a multicenter prospective cohort study evaluating sport activity and development of femoroacetabular impingement in the adolescent hip  Journal Articles
• Protocol for a multicenter randomized controlled trial comparing a non-opioid prescription to the standard of care for pain control following arthroscopic knee and shoulder surgery  Journal Articles
• Protocol for a multicentre, randomised, parallel-control, superiority trial comparing administration of clotting factor concentrates with a standard massive haemorrhage protocol in severely bleeding trauma patients: the FiiRST 2 trial (a 2020 EAST multicentre trial)  Journal Articles
• Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study).  Journal Articles
• Protocol for a randomised controlled trial to evaluate the effectiveness of improving tuberculosis patients’ treatment adherence via electronic monitors and an app versus usual care in Tibet  Journal Articles
• Protocol for a randomised trial evaluating a preconception-early childhood telephone-based intervention with tailored e-health resources for women and their partners to optimise growth and development among children in Canada: a Healthy Life Trajectory Initiative (HeLTI Canada)  Journal Articles
• Protocols for multi‐site trials using hyperpolarized ¹²⁹Xe MRI for imaging of ventilation, alveolar‐airspace size, and gas exchange: A position paper from the ¹²⁹Xe MRI clinical trials consortium  Journal Articles
• Qualidade de Vida Relacionada à Saúde e Desfechos em Longo Prazo após COVID-19 Sintomática Leve: Protocolo do Estudo Pós-COVID Brasil 2  Journal Articles
• Qualidade de Vida em Longo Prazo e Desfechos após Internação por COVID-19 no Brasil: Protocolo do Estudo Pós-COVID Brasil 1  Journal Articles
• Quality of anticoagulation and use of warfarin-interacting medications in long-term care: A chart review  Journal Articles
• Quality-of-Life Assessment: Patient Compliance With Questionaire Completion  Journal Articles
• Quantitative muscle analysis in facioscapulohumeral muscular dystrophy using whole‐body fat‐referenced MRI: Protocol development, multicenter feasibility, and repeatability  Journal Articles
• Randomization and concealment in surgical trials: a comparison between orthopaedic and non-orthopaedic randomized trials  Journal Articles
• Randomized Clinical Trials — Removing Unnecessary Obstacles  Journal Articles
• Rapid normalization of vitamin D deficiency in PICU (VITdALIZE-KIDS): study protocol for a phase III, multicenter randomized controlled trial.  Journal Articles
• Rationale and Design of the Statin Use in Intracerebral Hemorrhage Patients (SATURN) Trial  Journal Articles
• Rationale and design of ePPOP-ID: a multicenter randomized controlled trial using an electronic-personalized program for obesity in pregnancy to improve delivery  Journal Articles
• Rationale and design of the PE-TRACT trial: A multicenter randomized trial to evaluate catheter-directed therapy for the treatment of intermediate-risk pulmonary embolism.  Journal Articles
• Rationale and design of the anticoagulant therapy after left atrial appendage closure (ATLAAC) trial.  Journal Articles
• Rationale, design, and organization of the PeriOperative ISchemic Evaluation (POISE) Trial: A randomized controlled trial of metoprolol versus placebo in patients undergoing noncardiac surgery  Journal Articles
• Rationale, design, implementation, and baseline characteristics of patients in the dig trial: A large, simple, long-term trial to evaluate the effect of digitalis on mortality in heart failure  Journal Articles
• Re-evaluation of peri-operative cardiac risk (the MET REPAIR study)  Journal Articles
• Reattachment rate with pneumatic retinopexy versus pars plana vitrectomy for single break rhegmatogenous retinal detachment.  Journal Articles
• Recommended Clinical Practices for Maximizing Peritoneal Dialysis Clearances  Journal Articles
• Reduction of cardiovascular events and microvascular complications in diabetes with ACE inhibitor treatment: HOPE and MICRO-HOPE  Journal Articles
• Refining risk classification in childhood B acute lymphoblastic leukemia: results of DFCI ALL Consortium Protocol 05-001  Journal Articles
• Reflections 1 Year Into the 21-Center National Institutes of Health–Funded WRIST Study: A Primer on Conducting a Multicenter Clinical Trial  Journal Articles
• Reflections on the challenges of conducting an international multicentre randomized controlled trial of balance training in addition to pulmonary rehabilitation and its impact on fall incidence in people with COPD  Journal Articles
• Relation of baseline characteristics to suppression of ventricular arrhythmias during placebo and active antiarrhythmic therapy in patients after myocardial infarction.  Journal Articles
• Relationship Between A1C and Fasting Plasma Glucose in Dysglycemia or Type 2 Diabetes  Journal Articles
• Relationship Between Perceived and Measured Changes in Walking After Stroke  Journal Articles
• Relationship of Activated Partial Thromboplastin Time to Coronary Events and Bleeding in Patients With Acute Coronary Syndromes Who Receive Heparin  Journal Articles
• Remote ischemic conditioning in necrotizing enterocolitis: study protocol of a multi-center phase II feasibility randomized controlled trial  Journal Articles
• Report From the Ethics Committee for Immunotherapy  Journal Articles
• Research ethics board approval for an international thromboprophylaxis trial  Journal Articles
• Resting state fMRI scanner instabilities revealed by longitudinal phantom scans in a multi-center study  Journal Articles
• STRIVE pilot trial: a protocol for a multicentre pragmatic internal pilot randomised controlled trial of Structured TRaining to Improve fitness in a Virtual Environment (STRIVE) before surgery.  Journal Articles
• Safety and Accuracy of Sentinel Lymph Node Biopsy Alone in Clinically Node-Positive Patients Undergoing Upfront Surgery for Invasive Breast Cancer: A Systematic Review  Journal Articles
• Satisfactory Analgesia with Minimal Emesis in Day Surgeries (SAME DayS): a protocol for a randomised controlled trial of morphine versus hydromorphone  Journal Articles
• Selective early medical treatment of the patent ductus arteriosus in extremely low gestational age infants: a pilot randomised controlled trial protocol (SMART-PDA)  Journal Articles
• Sex-Based Analysis of Workflow and Outcomes in Acute Ischemic Stroke Patients Treated With Alteplase Versus Tenecteplase  Journal Articles
• Sharing of Lessons Learned From Multisite Research  Journal Articles
• Short-course antimicrobial therapy for paediatric respiratory infections (SAFER): study protocol for a randomized controlled trial  Journal Articles
• Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies  Journal Articles
• Solute Clearance Approach to Adequacy of Peritoneal Dialysis  Journal Articles
• Specific barriers to the conduct of randomized trials  Journal Articles
• Standard Surgical Protocol to Treat Elbow Dislocations with Radial Head and Coronoid Fractures  Journal Articles
• Statins and Intracerebral Hemorrhage  Journal Articles
• Statistical analysis plan for a cluster-randomised trial assessing the effectiveness of implementation of a bedside evidence-based checklist for clinical management of brain-dead potential organ donors in intensive care units: DONORS (Donation Network to Optimise Organ Recovery Study)  Journal Articles
• Statistical analysis plan for a cluster-randomized crossover trial comparing the effectiveness and safety of a flexible family visitation model for delirium prevention in adult intensive care units (the ICU Visits Study)  Journal Articles
• Statistical analysis plan for the Pneumatic CompREssion for PreVENting Venous Thromboembolism (PREVENT) trial: a study protocol for a randomized controlled trial  Journal Articles
• Stereotactic ablative radiotherapy for the comprehensive treatment of 1–3 Oligometastatic tumors (SABR-COMET-3): study protocol for a randomized phase III trial  Journal Articles
• Strategies to detect abnormal glucose metabolism in people at high risk of cardiovascular disease from the ORIGIN (Outcome Reduction with Initial Glargine Intervention) trial population  Journal Articles
• Structured diet and exercise guidance in pregnancy to improve health in women and their offspring: study protocol for the Be Healthy in Pregnancy (BHIP) randomized controlled trial  Journal Articles
• Studies of Left Ventricular Dysfunction (SOLVD)—Rationale, design and methods: Two trials that evaluate the effect of enalapril in patients with reduced ejection fraction  Journal Articles
• Study protocol for the randomized controlled trial of EMBOLDEN: a multifaceted intervention aimed at Enhancing physical and community MoBility in OLDEr adults with health inequities using commuNity co-design.  Journal Articles
• Study protocol for two complementary trials of non-steroidal or opioid analgesia use for children aged 6 to 17 years with musculoskeletal injuries (the No OUCH study)  Journal Articles
• Study protocol of a phase 2, randomised, placebo-controlled, double-blind, adaptive, parallel group clinical study to evaluate the efficacy and safety of recombinant alpha-1-microglobulin in subjects at high risk for acute kidney injury following open-chest cardiac surgery (AKITA trial)  Journal Articles
• Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy  Journal Articles
• TB and COVID-19 co-infection: rationale and aims of a global study  Journal Articles
• THE CANADIAN AMERICAN TICLOPIDINE STUDY (CATS) IN THROMBOEMBOLIC STROKE  Journal Articles
• TILE pilot trial study protocol: Tinzaparin Lead-in to Prevent the Post-Thrombotic syndrome study protocol  Journal Articles
• Team approach to polypharmacy evaluation and reduction: study protocol for a randomized controlled trial  Journal Articles
• TeleRehabilitation with Aims to Improve Lower extremity recovery in community-dwelling individuals who have had a stroke: protocol for a multisite, parallel group, assessor-blinded, randomised attention-controlled trial  Journal Articles
• Temporal Trends and Factors Associated With the Inclusion of Patient‐Reported Outcomes in Heart Failure Randomized Controlled Trials: A Systematic Review  Journal Articles
• The Analysis of Multinational Cost-Effectiveness Data for Reimbursement Decisions  Journal Articles
• The BEACON study: protocol for a cohort study as part of an evaluation of the effectiveness of smartphone-assisted problem-solving therapy in men who present with intentional self-harm to emergency departments in Ontario  Journal Articles
• The CHORUS (Cerivastatin in Heart Outcomes in Renal Disease: Understanding Survival) protocol: A double-blind, placebo-controlled trial in patients with ESRD  Conferences
• The CHORUS (Cerivastatin in Heart Outcomes in Renal Disease: Understanding Survival) protocol: a double-blind, placebo-controlled trial in patients with esrd.  Journal Articles
• The Canadian American Ticlopidine Study (CATS) in thromboembolic stroke. Design, organization, and baseline results.  Journal Articles
• The Canadian Lung Outcomes in Users of Vaping Devices (CLOUD) Study: protocol for a prospective, observational cohort study.  Journal Articles
• The Canadian Optimal Therapy of COPD Trial: Design, Organization and Patient Recruitment  Journal Articles
• The Complexity of Conducting a Multicenter Clinical Trial: Taking It to the Next Level Stipulated by the Federal Agencies  Journal Articles
• The Diaphragmatic Initiated Ventilatory Assist (DIVA) trial: study protocol for a randomized controlled trial comparing rates of extubation failure in extremely premature infants undergoing extubation to non-invasive neurally adjusted ventilatory assist versus non-synchronized nasal intermittent positive pressure ventilation  Journal Articles
• The Efficacy of Glutamine Supplementation in Severe Adult Burn Patients: A Systematic Review With Trial Sequential Meta-Analysis  Journal Articles
• The Fluid Study Protocol: A Randomized Controlled Study on the Effects of Bioimpedance Analysis and Vitamin D on Left Ventricular Mass in Peritoneal Dialysis Patients  Journal Articles
• The INVICTUS rheumatic heart disease research program: Rationale, design and baseline characteristics of a randomized trial of rivaroxaban compared to vitamin K antagonists in rheumatic valvular disease and atrial fibrillation  Journal Articles
• The Inhaled Steroid Treatment as Regular Therapy in Early Asthma (START) Study  Journal Articles
• The Internet and Clinical Trials: Background, Online Resources, Examples and Issues  Journal Articles
• The Public Access Defibrillation (PAD) Trial  Journal Articles
• The Salmeterol Multicenter Asthma Research Trial  Journal Articles
• The Stability study: a protocol for a multicenter randomized clinical trial comparing anterior cruciate ligament reconstruction with and without Lateral Extra-articular Tenodesis in individuals who are at high risk of graft failure  Journal Articles
• The Surveillance After Extremity Tumor Surgery (SAFETY) trial: protocol for a pilot study to determine the feasibility of a multi-centre randomised controlled trial  Journal Articles
• The Tactics of Large Randomized Trials  Journal Articles
• The Transitions to Long-term In Home Ventilator Engagement Study (Transitions to LIVE): study protocol for a pragmatic randomized controlled trial  Journal Articles
• The Value of Washers in Cannulated Screw Fixation of Femoral Neck Fractures  Journal Articles
• The cost implications of the use of telmisartan or ramipril in patients at high risk for vascular events: the ONTARGET study  Journal Articles
• The effect of enteral nutrition strategy and non-invasive ventilation on diarrhea and nutritional goals in the critically ill: A protocol for a multicentre retrospective cohort study (ENND GOALS).  Journal Articles
• The effects of nocturnal hemodialysis compared to conventional hemodialysis on change in left ventricular mass: Rationale and study design of a randomized controlled pilot study  Journal Articles
• The left atrial appendage exclusion for prophylactic stroke reduction (LEAAPS) trial: Rationale and design.  Journal Articles
• The long-term intercorrelation between post-burn pain, anxiety, and depression: a post hoc analysis of the “RE-ENERGIZE” double-blind, randomized, multicenter placebo-controlled trial  Journal Articles
• The role of the data coordinating center in the DIG trial  Journal Articles
• The role of the data coordinating center in the IRB review and approval process: the DIG trial experience  Journal Articles
• The role of the pharmacy coordinating center in the DIG trial  Journal Articles
• The “parallel-cohort RCT”: Novel design aspects and application in the Kids-DOTT trial of pediatric venous thromboembolism  Journal Articles
• Thrombosis prophylaxis in the acutely ill medical patient: insights from the prophylaxis in medical patients with enoxaparin (MEDENOX) trial  Journal Articles
• Tissue plasminogen activator: Toronto (TPAT) placebo-controlled randomized trial in acute myocardial infarction  Journal Articles
• Tocilizumab did not reduce hypoxemic respiratory failure or death in hospitalized patients with COVID-19  Journal Articles
• Transition to Adulthood through Coaching and Empowerment in Rheumatology (TRACER): A feasibility study protocol.  Journal Articles
• Treat-to-target of endoscopic remission in patients with inflammatory bowel disease in symptomatic remission on advanced therapies (QUOTIENT): rationale, design and protocol for an open-label, multicentre, pragmatic, randomised controlled trial.  Journal Articles
• Treatment Strategies in Elderly Patients with Aggressive Histology Lymphoma  Journal Articles
• Treatment-Dose LMWH versus Prophylactic/Intermediate Dose Heparins in High-Risk COVID-19 Inpatients: Rationale and Design of the HEP-COVID Trial  Journal Articles
• Trends in the utilization and wastage of coagulation factor concentrates: the application of a regional tracking programme  Journal Articles
• Ultrasound-Guided Transfemoral Access for Coronary Procedures: A Pooled Learning Curve Analysis From the FAUST and UNIVERSAL Trials  Journal Articles
• Understanding the use and outcomes of high-flow nasal cannula among infants admitted to Canadian hospitals with bronchiolitis (CanFLO): a protocol for a multicentre, retrospective cohort study  Journal Articles
• Use of Modified Multiplier of the Simple Endoscopic Score for Crohn's Disease Endoscopic Improvement Thresholds Enhances Effect Size Differentiation Between Adalimumab Versus Placebo: A Post Hoc Analysis of the EXTEND Trial.  Journal Articles
• Use of the day 6 bone marrow to alter remission induction therapy in patients with acute myeloid leukaemia: a leukemia intergroup study  Journal Articles
• Variations between countries in invasive cardiac procedures  Journal Articles
• What counts as patient-important upper gastrointestinal bleeding in the ICU? A mixed-methods study protocol of patient and family perspectives  Journal Articles
• Will this trial change my practice? TASTE - a randomised registry on thrombus aspiration in primary PCI with a 30-day endpoint  Journal Articles
• Work Productivity and Healthcare Resource Utilization Outcomes for Patients on Etanercept for Moderate-to-Severe Plaque Psoriasis  Journal Articles
• Xylitol for the prevention of acute otitis media episodes in children aged 2–4 years: protocol for a pragmatic randomised controlled trial  Journal Articles