Journal article
Lessons learned from the DIG trial
Abstract
The Digitalis Investigation Group (DIG) trial was the first large simple trial conducted by the National Heart, Lung, and Blood Institute in conjunction with the Department of Veterans Affairs. A large simple trial is a major undertaking. Simplification at the sites requires careful planning and discipline. Lessons learned from the DIG trial were: (1) keep a large simple trial very simple and keep all study procedures very simple; (2) ancillary …
Authors
Egan D; Geller N; Yusuf S; Garg R; Collins JF; Mathew J; Philbin E; Investigators OBOTD
Journal
Contemporary Clinical Trials, Vol. 24, No. 6, pp. s316–s326
Publisher
Elsevier
Publication Date
December 2003
DOI
10.1016/s0197-2456(03)00099-0
ISSN
1551-7144