Journal article
Neoadjuvant chemotherapy versus debulking surgery in advanced tubo-ovarian cancers: pooled analysis of individual patient data from the EORTC 55971 and CHORUS trials
Abstract
BACKGROUND: Individual patient data from two randomised trials comparing neoadjuvant chemotherapy with upfront debulking surgery in advanced tubo-ovarian cancer were analysed to examine long-term outcomes for patients and to identify any preferable therapeutic approaches for subgroup populations.
METHODS: We did a per-protocol pooled analysis of individual patient data from the European Organisation for Research and Treatment of Cancer (EORTC) …
Authors
Vergote I; Coens C; Nankivell M; Kristensen GB; Parmar MKB; Ehlen T; Jayson GC; Johnson N; Swart AM; Verheijen R
Journal
The Lancet Oncology, Vol. 19, No. 12, pp. 1680–1687
Publisher
Elsevier
Publication Date
December 2018
DOI
10.1016/s1470-2045(18)30566-7
ISSN
1470-2045
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedCytoreduction Surgical ProceduresFallopian Tube NeoplasmsFemaleGynecologic Surgical ProceduresHumansMiddle AgedMulticenter Studies as TopicNeoadjuvant TherapyNeoplasm StagingOvarian NeoplasmsPeritoneal NeoplasmsProgression-Free SurvivalRandomized Controlled Trials as TopicRisk FactorsTime FactorsTumor Burden