Journal article
Fondaparinux vs Enoxaparin for the Prevention of Venous Thromboembolism in Major Orthopedic Surgery: A Meta-analysis of 4 Randomized Double-blind Studies
Abstract
BACKGROUND: Orthopedic surgery remains a condition at high risk of venous thromboembolism (VTE). Fondaparinux, the first of a new class of synthetic selective factor Xa inhibitors, may further reduce this risk compared with currently available thromboprophylactic treatments.
METHODS: A meta-analysis of 4 multicenter, randomized, double-blind trials in patients undergoing elective hip replacement, elective major knee surgery, and surgery for hip …
Authors
Turpie AGG; Bauer KA; Eriksson BI; Lassen MR
Journal
JAMA Internal Medicine, Vol. 162, No. 16, pp. 1833–1840
Publisher
American Medical Association (AMA)
Publication Date
September 9, 2002
DOI
10.1001/archinte.162.16.1833
ISSN
2168-6106
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AgedAnticoagulantsArthroplasty, Replacement, HipArthroplasty, Replacement, KneeConfidence IntervalsDouble-Blind MethodEnoxaparinFemaleFibrinolytic AgentsFondaparinuxFracture Fixation, InternalHip FracturesHumansIncidenceMaleMiddle AgedMulticenter Studies as TopicOrthopedic ProceduresPolysaccharidesRandomized Controlled Trials as TopicThromboembolismTime FactorsTreatment OutcomeVenous Thrombosis