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Plasma Matrix Metalloproteinase-9 Level Is...
Journal article

Plasma Matrix Metalloproteinase-9 Level Is Correlated With Left Ventricular Volumes and Ejection Fraction in Patients With Heart Failure

Abstract

BACKGROUND: Matrix metalloproteinases (MMPs) can alter myocardial extracellular matrix and thereby contribute to adverse ventricular remodeling in progressive heart failure (HF). We hypothesized that increased plasma MMP levels correlate with increased left ventricular (LV) volumes and reduced LV ejection fraction (LVEF) in patients with HF. METHODS AND RESULTS: In the Randomized Evaluation of Strategies for Left Ventricular Dysfunction …

Authors

Yan AT; Yan RT; Spinale FG; Afzal R; Gunasinghe HR; Arnold M; Demers C; Mckelvie RS; Liu PP

Journal

Journal of Cardiac Failure, Vol. 12, No. 7, pp. 514–519

Publisher

Elsevier

Publication Date

September 2006

DOI

10.1016/j.cardfail.2006.05.012

ISSN

1071-9164