Refining risk classification in childhood B acute lymphoblastic leukemia: results of DFCI ALL Consortium Protocol 05-001 Academic Article uri icon

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abstract

  • Key Points Childhood B-ALL patients, including those with VHR features, had favorable outcomes on DFCI 05-001 risk-stratified therapy. IKZF1 deletion was an independent predictor of inferior outcome, including among patients with low end-induction MRD.

authors

  • Vrooman, Lynda M
  • Blonquist, Traci M
  • Harris, Marian H
  • Stevenson, Kristen E
  • Place, Andrew E
  • Hunt, Sarah K
  • O’Brien, Jane E
  • Asselin, Barbara L
  • Athale, Uma
  • Clavell, Luis A
  • Cole, Peter D
  • Kelly, Kara M
  • Laverdiere, Caroline
  • Leclerc, Jean-Marie
  • Michon, Bruno
  • Schorin, Marshall A
  • Sulis, Maria Luisa
  • Welch, Jennifer JG
  • Neuberg, Donna S
  • Sallan, Stephen E
  • Silverman, Lewis B

publication date

  • June 26, 2018

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