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Efficacy of cholesterol-lowering therapy in 18 686...
Journal article

Efficacy of cholesterol-lowering therapy in 18 686 people with diabetes in 14 randomised trials of statins: a meta-analysis

Abstract

BACKGROUND: Although statin therapy reduces the risk of occlusive vascular events in people with diabetes mellitus, there is uncertainty about the effects on particular outcomes and whether such effects depend on the type of diabetes, lipid profile, or other factors. We undertook a prospective meta-analysis to help resolve these uncertainties. METHODS: We analysed data from 18 686 individuals with diabetes (1466 with type 1 and 17,220 with type …

Authors

Kearney PM; Blackwell L; Collins R; Keech A; Simes J; Peto R; Armitage J; Baigent C

Journal

The Lancet, Vol. 371, No. 9607, pp. 117–125

Publisher

Elsevier

Publication Date

1 2008

DOI

10.1016/s0140-6736(08)60104-x

ISSN

0140-6736