Diabetes mellitus, a predictor of morbidity and mortality in the studies of left ventricular dysfunction (SOLVD) trials and registry Journal Articles uri icon

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  • Diabetes is an independent predictor of morbidity and mortality in patients with symptomatic heart failure, patients with asymptomatic left ventricular dysfunction (defined as an ejection fraction of 35% or less), and in a broader registry population with less stringent entry criteria. Although the SOLVD Trials made a major clinical contribution by proving the value of enalapril, diabetes remains a significant predictor of outcome even after adjusting for treatment with enalapril.


  • Shindler, Daniel M
  • Kostis, John B
  • Yusuf, Salim
  • Quinones, Miguel A
  • Pitt, Bertram
  • Stewart, Dawn
  • Pinkett, Tamara
  • Ghali, Jalal K
  • Wilson, Alan C
  • The SOLVD Investigators

publication date

  • May 1996

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