The Public Access Defibrillation (PAD) Trial Journal Articles uri icon

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  • The PAD Trial is a prospective, multicenter, randomized clinical study testing whether volunteer, non-medical responders can improve survival from out-of-hospital cardiac arrest (OOH-CA) by using automated external defibrillators (AEDs). These lay volunteers, who have no traditional responsibility to respond to a medical emergency as part of their primary job description, will form part of a comprehensive, integrated community approach to the treatment of OOH-CA. The study is being conducted at 24 field centers in the United States and Canada. Approximately 1000 community units (e.g. apartment or office buildings, gated communities, sports facilities, senior centers, shopping malls, etc.) were randomized to treatment by trained laypersons who will provide either cardiopulmonary resuscitation (CPR) alone or CPR plus use of an AED, while awaiting arrival of the community's emergency medical services responders. The primary endpoint is the number of OOH-CA victims who survive to hospital discharge. Secondary endpoints include neurological status, health-related quality of life (HRQL), cost, and cost-effectiveness. Data collection will last approximately 15 months and is expected to be completed in September 2003.


  • Feeny, David
  • Ornato, Joseph P
  • McBurnie, Mary Ann
  • Nichol, Graham
  • Salive, Marcel
  • Weisfeldt, Myron
  • Riegel, Barbara
  • Christenson, James
  • Terndrup, Thomas
  • Daya, Mohamud
  • PAD Trial Investigators

publication date

  • February 2003

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