Journal article
Xylitol for the prevention of acute otitis media episodes in children aged 2–4 years: protocol for a pragmatic randomised controlled trial
Abstract
INTRODUCTION: Xylitol (or 'birch sugar') is a naturally occurring sugar with antibacterial properties that has been used as a natural non-sugar sweetener in chewing gums, confectionery, toothpaste and medicines. In this preventative randomised trial, xylitol will be tested for the prevention of acute otitis media (AOM), a common and costly condition in young children. The primary outcome will be the incidence of AOM. Secondary outcomes will …
Authors
Persaud N; Laupacis A; Azarpazhooh A; Birken C; Hoch JS; Isaranuwatchai W; Maguire JL; Mamdani MM; Thorpe K; Allen C
Journal
BMJ Open, Vol. 8, No. 8,
Publisher
BMJ
Publication Date
August 2018
DOI
10.1136/bmjopen-2017-020941
ISSN
2044-6055