Brain-Derived Neurotrophic Factor
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Overview
subject area of
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BDNF Val66Met polymorphism and peripheral protein levels in pediatric bipolar disorder and attention‐deficit/hyperactivity disorder Journal Articles
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A Single Bout of High-intensity Interval Exercise Increases Corticospinal Excitability, Brain-derived Neurotrophic Factor, and Uncarboxylated Osteolcalcin in Sedentary, Healthy Males Journal Articles
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A gastrin-releasing peptide receptor antagonist blocks d-amphetamine-induced hyperlocomotion and increases hippocampal NGF and BDNF levels in rats Journal Articles
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A longitudinal study of neurotrophic, oxidative, and inflammatory markers in first-onset depression in midlife women Journal Articles
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A nerve growth factor peptide retards seizure development and inhibits neuronal sprouting in a rat model of epilepsy. Journal Articles
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A new brain‐derived neurotrophic factor transcript and decrease inbrain‐derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex Journal Articles
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A novel anticonvulsant modulates voltage‐gated sodium channel inactivation and prevents kindling‐induced seizures Journal Articles
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Accelerated age-related decrease in brain-derived neurotrophic factor levels in bipolar disorder Journal Articles
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Activin mRNA induced during amygdala kindling shows a spatiotemporal progression that tracks the spread of seizures Journal Articles
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Activity Regulates Positive and Negative Neurotrophin-Derived Signals to Determine Axon Competition Journal Articles
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Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus Journal Articles
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Acute harmine administration induces antidepressive-like effects and increases BDNF levels in the rat hippocampus Journal Articles
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Acute low dose of MK-801 prevents memory deficits without altering hippocampal DARPP-32 expression and BDNF levels in sepsis survivor rats Journal Articles
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Adjunctive tianeptine treatment for bipolar disorder: A 24-week randomized, placebo-controlled, maintenance trial Journal Articles
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Agreement in DNA methylation levels from the Illumina 450K array across batches, tissues, and time Journal Articles
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Altered Balance of Proteolytic Isoforms of Pro-Brain-Derived Neurotrophic Factor in Autism Journal Articles
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Anxiety disorders in childhood are associated with youth IL-6 levels: A mediation study including metabolic stress and childhood traumatic events Journal Articles
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Assessing brain-derived neurotrophic factor as a novel clinical marker of endometriosis Journal Articles
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Association between BDNF levels and suicidal behaviour: a systematic review and meta-analysis Journal Articles
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Association between BDNF levels and suicidal behaviour: a systematic review protocol Journal Articles
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Association of serum brain-derived neurotrophic factor (BDNF) and tumor necrosis factor-alpha (TNF-α) with diagnosis of delirium in oncology inpatients Journal Articles
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Association study of brain‐derived neurotrophic factor (BDNF) and LIN‐7 homolog (LIN‐7) genes with adult attention‐deficit/hyperactivity disorder Journal Articles
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Associations between parenting behavior and anxiety in a rodent model and a clinical sample: relationship to peripheral BDNF levels Journal Articles
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Attenuation of mania-like behavior in Na+,K+-ATPase α3 mutant mice by prospective therapies for bipolar disorder: Melatonin and exercise Journal Articles
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BDNF and NT-3 regulation of trkB and trkC mRNA levels in the developing chick spinal cord Journal Articles
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BDNF and PDE4, but not the GRPR, Regulate Viability of Human Medulloblastoma Cells Journal Articles
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BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog Journal Articles
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BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism Journal Articles
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BDNF-Dependent Effects on Amygdala–Cortical Circuitry and Depression Risk in Children and Youth Journal Articles
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BDNF/TrkB Content and Interaction with Gastrin-Releasing Peptide Receptor Blockade in Colorectal Cancer Journal Articles
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BDNF: A biomarker for social vulnerability in individuals diagnosed with gender dysphoria Journal Articles
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Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid Journal Articles
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Biomarkers in bipolar disorder: A positional paper from the International Society for Bipolar Disorders Biomarkers Task Force Journal Articles
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Brain-derived neurotrophic factor (BDNF) expression and function in the mammalian reproductive Tract Journal Articles
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Brain-derived neurotrophic factor and TrkB expression in the “oldest-old,” the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta Journal Articles
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Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder Journal Articles
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Brain-derived neurotrophic factor and neuron-specific enolase, but not S100β, levels are associated to the occurrence of delirium in intensive care unit patients Journal Articles
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Brain-derived neurotrophic factor and neuroplasticity in bipolar disorder Journal Articles
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Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: A systematic review and meta-regression analysis Journal Articles
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Brain-derived neurotrophic factor expression in granulosa lutein cells Journal Articles
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Brain-derived neurotrophic factor gene val66met polymorphism and executive functioning in patients with bipolar disorder Journal Articles
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Brain-derived neurotrophic factor infusion delays amygdala and perforant path kindling without affecting paired-pulse measures of neuronal inhibition in adult rats Journal Articles
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Brain-derived neurotrophic factor is associated with human muscle satellite cell differentiation in response to muscle-damaging exercise Journal Articles
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Brain-derived neurotrophic factor serum levels before and after treatment for acute mania Journal Articles
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Brain-derived neurotrophic factor serum levels following ketamine and esketamine intervention for treatment-resistant depression: secondary analysis from a randomized trial Journal Articles
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Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder Journal Articles
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Brain-derived neurotrophic factor variants are associated with childhood-onset mood disorder: confirmation in a Hungarian sample Journal Articles
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Brain‐derived neurotrophic factor and inflammatory markers in school‐aged children with early trauma Journal Articles
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Brain‐derived neurotrophic factor in bipolar disorder: beyond trait and state: comment on ‘Decreased levels of serum brain‐derived neurotrophic factor in both depressed and euthymic patients with unipolar depression and in euthymic patients with bipolar I and II disorders’ Journal Articles
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Brain‐derived neurotrophic factor, impaired glucose metabolism, and bipolar disorder course Journal Articles
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CREB expression mediates amyloid β-induced basal BDNF downregulation Journal Articles
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Cell therapy in the treatment of bipolar mania in an animal model: a proof of concept study Journal Articles
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Cerebrospinal Fluid proNGF: A Putative Biomarker for Early Alzheimer's Disease Journal Articles
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Changes in the Brain-Derived Neurotrophic Factor Are Associated with Improvements in Diabetes Risk Factors after Exercise Training in Adolescents with Obesity: The HEARTY Randomized Controlled Trial Journal Articles
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Chronic Administration of Ketamine Elicits Antidepressant‐Like Effects in Rats without Affecting Hippocampal Brain‐Derived Neurotrophic Factor Protein Levels Journal Articles
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Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice Journal Articles
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Chronic Mild Stress Paradigm Reduces Sweet Food Intake in Rats without Affecting Brain Derived Neurotrophic Factor Protein Levels Journal Articles
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Chronic administration of harmine elicits antidepressant-like effects and increases BDNF levels in rat hippocampus Journal Articles
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Clinical staging and serum cytokines in bipolar patients during euthymia Journal Articles
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Cognitive function and serum levels of brain‐derived neurotrophic factor in patients with bipolar disorder Journal Articles
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Contribution of BDNF and DRD2 genetic polymorphisms to continued opioid use in patients receiving methadone treatment for opioid use disorder: an observational study Journal Articles
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Correlation between Peripheral Levels of Brain-Derived Neurotrophic Factor and Hippocampal Volume in Children and Adolescents with Bipolar Disorder Journal Articles
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Correlation between behavioral deficits and decreased brain-derived neurotrofic factor in neonatal meningitis Journal Articles
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Correlation between n-3 polyunsaturated fatty acids consumption and BDNF peripheral levels in adolescents Journal Articles
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Decreased Brain-Derived Neurotrophic Factor Depends on Amyloid Aggregation State in Transgenic Mouse Models of Alzheimer's Disease Journal Articles
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Decreased Plasma Brain Derived Neurotrophic Factor Levels in Unmedicated Bipolar Patients During Manic Episode Journal Articles
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Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients Journal Articles
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Dentate granule cell layer collagen explant cultures: Spontaneous axonal growth and induction by brain-derived neurotrophic factor or basic fibroblast growth factor Journal Articles
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Depressive-Like Parameters in Sepsis Survivor Rats Journal Articles
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Developmental and Lactational Exposure to Dieldrin Alters Mammary Tumorigenesis in Her2/neu Transgenic Mice Journal Articles
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Developmental axon pruning mediated by BDNF-p75NTR–dependent axon degeneration Journal Articles
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Differences in biomarkers of crack-cocaine adolescent users before/after abstinence Journal Articles
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Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease Journal Articles
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Does ceasing exercise induce depressive symptoms? A systematic review of experimental trials including immunological and neurogenic markers Journal Articles
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Downhill training upregulates mice hippocampal and striatal brain-derived neurotrophic factor levels Journal Articles
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Early intervention in bipolar disorders: Clinical, biochemical and neuroimaging imperatives Journal Articles
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Early life stress decreases hippocampal BDNF content and exacerbates recognition memory deficits induced by repeated d-amphetamine exposure Journal Articles
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Effect of non‐invasive brain stimulation on behavior and serum brain‐derived neurotrophic factor and insulin‐like growth factor‐1 levels in autistic patients Journal Articles
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Effect of diesel exhaust inhalation on blood markers of inflammation and neurotoxicity: a controlled, blinded crossover study Journal Articles
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Effects of a single bout of maximal aerobic exercise on BDNF in bipolar disorder: A gender-based response Journal Articles
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Effects of aerobic training, resistance training, or both on brain-derived neurotrophic factor in adolescents with obesity: The hearty randomized controlled trial Journal Articles
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Effects of cannabidiol on amphetamine-induced oxidative stress generation in an animal model of mania Journal Articles
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Effects of childhood trauma on BDNF and TBARS during crack-cocaine withdrawal Journal Articles
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Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase acitivity in the hippocampus of survivor mice Journal Articles
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Effects of increased opportunity for physical exercise and learning experiences on recognition memory and brain-derived neurotrophic factor levels in brain and serum of rats Journal Articles
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Effects of moderate exercise on cigarette smoke exposure-induced hippocampal oxidative stress values and neurological behaviors in mice Journal Articles
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Effects of mood stabilizers on hippocampus BDNF levels in an animal model of mania Journal Articles
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Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain Journal Articles
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Effects of β-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: Further evidence of antidepressant properties Journal Articles
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Electrical muscle stimulation elevates intramuscular BDNF and GDNF mRNA following peripheral nerve injury and repair in rats Journal Articles
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Enhanced BDNF signalling following chronic hypoxia potentiates catecholamine release from cultured rat adrenal chromaffin cells Journal Articles
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Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors Journal Articles
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Ethanol during adolescence decreased the BDNF levels in the hippocampus in adult male Wistar rats, but did not alter aggressive and anxiety-like behaviors Journal Articles
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Evaluation of cytokines, oxidative stress markers and brain-derived neurotrophic factor in patients with fibromyalgia – A controlled cross-sectional study Journal Articles
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Evaluation of natriuretic peptide recommendations in heart failure clinical practice guidelines Journal Articles
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Evidence for an association of serum microanalytes and myofascial pain syndrome Journal Articles
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Exercise and circulating BDNF: Mechanisms of release and implications for the design of exercise interventions Journal Articles
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Exercise-Induced Neuroplasticity: A Mechanistic Model and Prospects for Promoting Plasticity Journal Articles
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Exploring the Association between Serum BDNF and Attempted Suicide Journal Articles
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Factors affecting stability of plasma brain-derived neurotrophic factor Journal Articles
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Fasting and exercise differentially regulate BDNF mRNA expression in human skeletal muscle Journal Articles
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Folic acid prevented cognitive impairment in experimental pneumococcal meningitis Journal Articles
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Gene expression of BDNF and its receptors, TrkB and p75 in the uterus and oviduct of pregnant and non-pregnant ewes Journal Articles
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Genetic Variation in
IL-1β, IL-2, IL-6, TSPO
and
BDNF
and Response to Duloxetine or Placebo Treatment in Major Depressive Disorder Journal Articles
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Genetic predictors of response to treatment with citalopram in depression secondary to traumatic brain injury Journal Articles
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Glucocorticoid Receptors, Brain-Derived Neurotrophic Factor, Serotonin and Dopamine Neurotransmission are Associated with Interferon-Induced Depression Journal Articles
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High Salt Intake Increases Blood Pressure via BDNF-Mediated Downregulation of KCC2 and Impaired Baroreflex Inhibition of Vasopressin Neurons Journal Articles
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High levels of brain-derived neurotrophic factor are associated with treatment adherence among crack-cocaine users Journal Articles
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Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania Journal Articles
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Imipramine reverses alterations in cytokines and BDNF levels induced by maternal deprivation in adult rats Journal Articles
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Imipramine treatment reverses depressive‐like behavior in alloxan‐diabetic rats Journal Articles
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Improvement of schizophrenia with electroconvulsive therapy and serum brain‐derived neurotrophic factor levels: Lack of association in a pilot study Journal Articles
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Increase in brain-derived neurotrophic factor expression in early crack cocaine withdrawal Journal Articles
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Increase in serum brain-derived neurotrophic factor levels during early withdrawal in severe alcohol users Journal Articles
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Increased oxidative stress as a mechanism for decreased BDNF levels in acute manic episodes Journal Articles
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Increased pro–nerve growth factor and decreased brain-derived neurotrophic factor in non–Alzheimer's disease tauopathies Journal Articles
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Intense Exercise Induces Mitochondrial Dysfunction in Mice Brain Journal Articles
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Intracerebral Administration of BDNF Protects Rat Brain Against Oxidative Stress Induced by Ouabain in an Animal Model of Mania Journal Articles
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Intraventricular administration of antibodies to nerve growth factor retards kindling and blocks mossy fiber sprouting in adult rats Journal Articles
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Ketamine alters behavior and decreases BDNF levels in the rat brain as a function of time after drug administration Journal Articles
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Ketamine impairs recognition memory consolidation and prevents learning-induced increase in hippocampal brain-derived neurotrophic factor levels Journal Articles
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Lack of effect of antipsychotics on BNDF and NGF levels in hippocampus of Wistar rats Journal Articles
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Long-lasting recognition memory impairment and alterations in brain levels of cytokines and BDNF induced by maternal deprivation: effects of valproic acid and topiramate Journal Articles
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Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease Journal Articles
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Mediator effects of parameters of inflammation and neurogenesis from a N-acetyl cysteine clinical-trial for bipolar depression Journal Articles
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Memantine treatment reverses anhedonia, normalizes corticosterone levels and increases BDNF levels in the prefrontal cortex induced by chronic mild stress in rats Journal Articles
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Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania Journal Articles
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Method for Electrochemical Detection of Brain Derived Neurotrophic Factor (BDNF) in Plasma Journal Articles
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Microbiota and host determinants of behavioural phenotype in maternally separated mice Journal Articles
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Mineralocorticoid receptor genotype moderates the association between physical neglect and serum BDNF Journal Articles
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Mitochondrial IV complex and brain neurothrophic derived factor responses of mice brain cortex after downhill training Journal Articles
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NGF, BDNF, NT-3, and GDNF mRNA Expression in Rat Skeletal Muscle following Denervation and Sensory Protection Journal Articles
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NT-3 modulates BDNF and proBDNF levels in naïve and kindled rat hippocampus Journal Articles
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Neurobiological Factors Linking Personality Traits and Major Depression Journal Articles
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Neurochemical and behavioural effects of acute and chronic memantine administration in rats: Further support for NMDA as a new pharmacological target for the treatment of depression? Journal Articles
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Neurocognitive performance in the context of acute symptom reduction in OCD: Treatment effects and the impact of BDNF Journal Articles
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Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation Journal Articles
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Neuronal Correlates of Brain-derived Neurotrophic Factor Val66Met Polymorphism and Morphometric Abnormalities in Bipolar Disorder Journal Articles
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Neurotrophic factors and Alzheimer’s disease: are we focusing on the wrong molecule? Journal Articles
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Neurotrophic growth factor responses to lower body resistance training in older adults Journal Articles
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Neurotrophins (BDNF and NGF) in follicular fluid of women with different infertility diagnoses Journal Articles
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Neurturin enhances the survival of axotomized retinal ganglion cells in vivo: combined effects with glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor Journal Articles
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No changes in corticospinal excitability, biochemical markers, and working memory after six weeks of high‐intensity interval training in sedentary males Journal Articles
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Nurr1 Is Not an Essential Regulator of BDNF in Mouse Cortical Neurons Journal Articles
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Object recognition memory and BDNF expression are reduced in young TgCRND8 mice Journal Articles
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Oligomeric Amyloid Decreases Basal Levels of Brain-Derived Neurotrophic factor (BDNF) mRNA via Specific Downregulation of BDNF Transcripts IV and V in Differentiated Human Neuroblastoma Cells Journal Articles
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Opium Effect in Pregnancy on the Dynamics of Maternal Behavior: Testing a Neurochemical Model Journal Articles
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Orienteering combines vigorous-intensity exercise with navigation to improve human cognition and increase brain-derived neurotrophic factor Journal Articles
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Oxidative stress and BDNF as possible markers for the severity of crack cocaine use in early withdrawal Journal Articles
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Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression. Journal Articles
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Peripheral biomarkers and illness activity in bipolar disorder Journal Articles
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Peripheral brain-derived neurotrophic factor changes along treatment with extended release quetiapine during acute mood episodes: An open-label trial in drug-free patients with bipolar disorder Journal Articles
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Physiological neuroprotection by melatonin in a 6-hydroxydopamine model of Parkinson's disease Journal Articles
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Plasma brain-derived neurotrophic factor levels, learning capacity and cognition in patients with first episode psychosis Journal Articles
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Precursor form of brain‐derived neurotrophic factor and mature brain‐derived neurotrophic factor are decreased in the pre‐clinical stages of Alzheimer's disease Journal Articles
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Prenatal restraint stress and motherless rearing disrupts expression of plasticity markers and stress-induced corticosterone release in adult female Sprague–Dawley rats Journal Articles
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Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer’s disease Journal Articles
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Psychophysiological correlates of cognitive deficits in family caregivers of patients with Alzheimer Disease Journal Articles
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Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease Journal Articles
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Reciprocal actions of interleukin‐6 and brain‐derived neurotrophic factor on rat and mouse primary sensory neurons Journal Articles
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Reduced Tissue Levels of Noradrenaline Are Associated with Behavioral Phenotypes of the TgCRND8 Mouse Model of Alzheimer's Disease Journal Articles
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Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele Journal Articles
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Reduced serum concentrations of brain-derived neurotrophic factor (BDNF) in transsexual Brazilian men Journal Articles
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Retrograde axonal transport of BDNF and proNGF diminishes with age in basal forebrain cholinergic neurons Journal Articles
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Screen time is independently associated with serum brain-derived neurotrophic factor (BDNF) in youth with obesity Journal Articles
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Serum BDNF levels in unaffected first-degree relatives of patients with bipolar disorder Journal Articles
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Serum BDNF levels increase during early drug withdrawal in alcohol and crack cocaine addiction Journal Articles
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Serum and plasma brain-derived neurotrophic factor concentration are elevated by systemic but not local passive heating Journal Articles
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Serum brain-derived neurotrophic factor (BDNF) is not associated with response to electroconvulsive therapy (ECT): A pilot study in drug resistant depressed patients Journal Articles
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Serum brain-derived neurotrophic factor and clozapine daily dose in patients with schizophrenia: A positive correlation Journal Articles
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Serum brain-derived neurotrophic factor in bipolar and unipolar depression: A potential adjunctive tool for differential diagnosis Journal Articles
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Serum brain-derived neurotrophic factor in patients with trauma psychopathology Journal Articles
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Serum brain-derived neurotrophic factor is decreased in bipolar disorder during depressive and manic episodes Journal Articles
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Serum concentrations of brain-derived neurotrophic factor in patients diagnosed with gender dysphoria undergoing sex reassignment surgery Journal Articles
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Serum concentrations of brain-derived neurotrophic factor in patients with gender identity disorder Journal Articles
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Serum levels of brain-derived neurotrophic factor and thiobarbituric acid reactive substances in chronically medicated schizophrenic patients: a positive correlation Journal Articles
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Serum levels of brain-derived neurotrophic factor in patients with schizophrenia and bipolar disorder Journal Articles
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Serum levels of brain-derived neurotrophic factor in schizophrenia on a hypocaloric diet Journal Articles
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Sex hormones and biomarkers of neuroprotection and neurodegeneration: implications for female reproductive events in bipolar disorder Journal Articles
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Sleep in bipolar patients Journal Articles
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Striatum brain-derived neurotrophic factor levels are decreased in dystrophin-deficient mice Journal Articles
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Synergistic effects of diet and exercise on hippocampal function in chronically stressed mice Journal Articles
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Systemic toxicity in early-stage mood disorders Journal Articles
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Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease Journal Articles
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The 5-HTTLPR and BDNF polymorphisms moderate the association between uncinate fasciculus connectivity and antidepressants treatment response in major depression Journal Articles
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The BDNF Val66Met polymorphism and health‐related quality of life in youth with obesity Journal Articles
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The Brain-Derived Neurotrophic Factor Val66Met Polymorphism, Hippocampal Volume, and Cognitive Function in Geriatric Depression Journal Articles
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The Brain-Uterus Connection: Brain Derived Neurotrophic Factor (BDNF) and Its Receptor (Ntrk2) Are Conserved in the Mammalian Uterus Journal Articles
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The Effects of Physical Exercise and Cognitive Training on Memory and Neurotrophic Factors Journal Articles
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The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice Journal Articles
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The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication Journal Articles
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The effects of aerobic exercise intensity on memory in older adults Journal Articles
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The effects of brain-derived neurotrophic factor (BDNF) administration on kindling induction, Trk expression and seizure-related morphological changes Journal Articles
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The influence of 5-HTTLPR and Val66Met polymorphisms on cortical thickness and volume in limbic and paralimbic regions in depression: a preliminary study Journal Articles
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Therapeutic use of omega-3 fatty acids in bipolar disorder Journal Articles
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Total and Mitochondrial Nitrosative Stress, Decreased Brain-Derived Neurotrophic Factor (BDNF) Levels and Glutamate Uptake, and Evidence of Endoplasmic Reticulum Stress in the Hippocampus of Vitamin A-Treated Rats Journal Articles
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Traumatic life events in bipolar disorder: impact on BDNF levels and psychopathology Journal Articles
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Val66Met polymorphism and serum brain‐derived neurotrophic factor in bipolar disorder: an open‐label trial Journal Articles
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Val66met polymorphism and serum brain-derived neurotrophic factor levels in bipolar disorder Journal Articles
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Vitamin B6 prevents cognitive impairment in experimental pneumococcal meningitis Journal Articles
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Vulnerability to dietary n-3 polyunsaturated fatty acid deficiency after exposure to early stress in rats Journal Articles
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White matter integrity in major depressive disorder: Implications of childhood trauma, 5-HTTLPR and BDNF polymorphisms Journal Articles