Journal article
Adjunctive tianeptine treatment for bipolar disorder: A 24-week randomized, placebo-controlled, maintenance trial
Abstract
OBJECTIVE: The purpose of this study was to assess the efficacy and tolerability of tianeptine as an adjunctive maintenance treatment for bipolar depression.
METHODS: This is a multicenter double-blind randomized placebo-controlled maintenance trial of adjunctive tianeptine 37.5 mg/day. Participants ( n=161) had a Montgomery-Asberg Depression Rating Scale ⩾12 at entry. After eight weeks of open-label tianeptine treatment, those who responded to …
Authors
Kauer-Sant’Anna M; Frey BN; Fijtman A; Loredo-Souza AC; Dargél AA; Pfaffenseller B; Wollenhaupt-Aguiar B; Gazalle FK; Colpo GD; Passos IC
Journal
Journal of Psychopharmacology, Vol. 33, No. 4, pp. 502–510
Publisher
SAGE Publications
Publication Date
April 2019
DOI
10.1177/0269881119826602
ISSN
0269-8811