Journal article
The Brain-Derived Neurotrophic Factor Val66Met Polymorphism, Hippocampal Volume, and Cognitive Function in Geriatric Depression
Abstract
OBJECTIVE: The Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene is associated with geriatric depression. In studies of younger adults without depression, met allele carriers exhibit smaller hippocampal volumes and have poorer performance on neuropsychological tests. The authors examined the relationship between the BDNF gene and hippocampal volumes in depressed and nondepressed older individuals and its relationship …
Authors
Benjamin S; McQuoid DR; Potter GG; Payne ME; MacFall JR; Steffens DC; Taylor WD
Journal
American Journal of Geriatric Psychiatry, Vol. 18, No. 4, pp. 323–331
Publisher
Elsevier
Publication Date
4 2010
DOI
10.1097/jgp.0b013e3181cabd2b
ISSN
1064-7481