Journal article
Brain-derived neurotrophic factor serum levels following ketamine and esketamine intervention for treatment-resistant depression: secondary analysis from a randomized trial
Abstract
OBJECTIVES: Evidence suggests that ketamine's influence on brain-derived neurotrophic factor (BDNF) might be involved in its mechanism of rapid antidepressant action. We aimed to evaluate the differential impact of ketamine and esketamine on serum BDNF levels and its association with response patterns in treatment-resistant depression (TRD).
METHODS: Participants (n = 53) are from a randomized, double-blind clinical trial comparing the efficacy …
Authors
Caliman-Fontes AT; Leal GC; Correia-Melo FS; Paixao CS; Carvalho MS; Jesus-Nunes AP; Vieira F; Magnavita G; Bandeira ID; Mello RP
Journal
Trends in Psychiatry and Psychotherapy, Vol. 45, ,
Publisher
EDITORA SCIENTIFIC
Publication Date
2023
DOI
10.47626/2237-6089-2021-0298
ISSN
2237-6089