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Brain-derived neurotrophic factor val66met...
Journal article

Brain-derived neurotrophic factor val66met polymorphism affects prefrontal energy metabolism in bipolar disorder

Abstract

Brain-derived neurotrophic factor val66met polymorphism has been implicated in the pathophysiology of bipolar disorder. We investigated the neurochemistry of the left dorsolateral prefrontal cortex of bipolar disorder and healthy participants in relation to the brain-derived neurotrophic factor val66met polymorphism using H-magnetic resonance spectroscopy. Absolute N-acetyl-aspartate, phosphocreatine+creatine (PCr+Cr), choline-containing …

Authors

Frey BN; Walss-Bass C; Stanley JA; Nery FG; Matsuo K; Nicoletti MA; Hatch JP; Bowden CL; Escamilla MA; Soares JC

Journal

Neuroreport, Vol. 18, No. 15, pp. 1567–1570

Publisher

Wolters Kluwer

Publication Date

October 8, 2007

DOI

10.1097/wnr.0b013e3282ef7082

ISSN

0959-4965