Protein Structure, Tertiary
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A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function Journal Articles
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A Control Switch for Prothrombinase Journal Articles
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A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP Journal Articles
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A Model for Agonism and Antagonism in an Ancient and Ubiquitous cAMP-binding Domain Journal Articles
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A New Target for Antibiotic Development Journal Articles
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A Non-Long Terminal Repeat Retrotransposon Family Is Restricted to the Germ Line Micronucleus of the Ciliated Protozoan
Tetrahymena thermophila Journal Articles
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A Novel Non-canonical Forkhead-associated (FHA) Domain-binding Interface Mediates the Interaction between Rad53 and Dbf4 Proteins Journal Articles
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A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus Journal Articles
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A Role of p73 in Mitotic Exit Journal Articles
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A Small Molecule Discrimination Map of the Antibiotic Resistance Kinome Journal Articles
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A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection Journal Articles
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A divergent Pseudomonas aeruginosa palmitoyltransferase essential for cystic fibrosis‐specific lipid A Journal Articles
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A homology model of the pore domain of a voltage-gated calcium channel is consistent with available SCAM data Journal Articles
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A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin Journal Articles
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A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both α- and β-ketone reduction during chain growth Journal Articles
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A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines Journal Articles
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Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII Journal Articles
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Active site labeling of the gentamicin resistance enzyme AAC(6')-APH(2") by the lipid kinase inhibitor wortmannin Journal Articles
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Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor α are altered by the centrosome-associated protein CAP350 Journal Articles
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Acyldepsipeptide Antibiotics Induce the Formation of a Structured Axial Channel in ClpP: A Model for the ClpX/ClpA-Bound State of ClpP Journal Articles
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AlgK Is a TPR-Containing Protein and the Periplasmic Component of a Novel Exopolysaccharide Secretin Journal Articles
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All three Ca2+‐binding loops of photoproteins bind calcium ions: The crystal structures of calcium‐loaded apo‐aequorin and apo‐obelin Journal Articles
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Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscle. Journal Articles
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Amphiphysin is a component of clathrin coats formed during synaptic vesicle recycling at the lamprey giant synapse. Journal Articles
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An Apolipoprotein AI Mimetic Peptide: Membrane Interactions and the Role of Cholesterol, Journal Articles
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An Ep-ICD Based Index Is a Marker of Aggressiveness and Poor Prognosis in Thyroid Carcinoma Journal Articles
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An Interbacterial NAD(P)+ Glycohydrolase Toxin Requires Elongation Factor Tu for Delivery to Target Cells Journal Articles
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An atypical proprotein convertase in Giardia lamblia differentiation Journal Articles
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An important role for the activation peptide domain in controlling factor IX levels in the blood of haemophilia B mice Conferences
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Antigen Interaction and Heat Inactivation Expose New Epitopes on Human IgE Journal Articles
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Architecture and Pore Block of Eukaryotic Voltage-Gated Sodium Channels in View of NavAb Bacterial Sodium Channel Structure Journal Articles
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Arginine Methylation Regulates Telomere Length and Stability Journal Articles
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Arkadia enhances nodal-related signalling to induce mesendoderm. Journal Articles
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Aryl Hydrocarbon Receptor-Dependent Retention of Nuclear HuR Suppresses Cigarette Smoke-Induced Cyclooxygenase-2 Expression Independent of DNA-Binding Journal Articles
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Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets Journal Articles
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Bax Forms an Oligomer via Separate, Yet Interdependent, Surfaces Journal Articles
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Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis Journal Articles
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Biosynthetic Pathway for Mannopeptimycins, Lipoglycopeptide Antibiotics Active against Drug-Resistant Gram-Positive Pathogens Journal Articles
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Botulinum neurotoxin homologs in non‐Clostridium species Journal Articles
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Bovine CLEC7A genetic variants and their association with seropositivity in Johne's disease ELISA Journal Articles
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CYB5D2 enhances HeLa cells survival of etoposide-induced cytotoxicity Journal Articles
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Characterization of Cereulide Synthetase, a Toxin-Producing Macromolecular Machine Journal Articles
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Characterization of DalS, an ATP-binding Cassette Transporter for d-Alanine, and Its Role in Pathogenesis in Salmonella enterica Journal Articles
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Characterization of a Distinctive Motif of the Low Molecular Weight Neurotrophin Receptor that Modulates NGF‐mediated Neurite Growth Journal Articles
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Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain Journal Articles
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Characterization of the C-terminal Domain of a Potassium Channel from Streptomyces lividans (KcsA) Journal Articles
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Characterization of the PilN, PilO and PilP type IVa pilus subcomplex Journal Articles
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Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels Chapters
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Computational Study of the Binding Modes of Caffeine to the Adenosine A2AReceptor Journal Articles
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Conformation of a double-membrane-spanning fragment of a G protein-coupled receptor: Effects of hydrophobic environment and pH Journal Articles
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Conserved domains of the class A scavenger receptors: evolution and function Journal Articles
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Conserved inserts in the Hsp60 (GroEL) and Hsp70 (DnaK) proteins are essential for cellular growth Journal Articles
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Control of Centromere Localization of the MEI-S332 Cohesion Protection Protein Journal Articles
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Cooperative and Critical Roles for Both G Domains in the GTPase Activity and Cellular Function of Ribosome-Associated
Escherichia coli
EngA Journal Articles
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Cross-chimeric analysis of selectivity of secretin and VPAC(1) receptor activation. Journal Articles
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Cryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factor Journal Articles
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Crystal Structure of Homoserine Transacetylase from Haemophilus influenzae Reveals a New Family of α/β-Hydrolases, Journal Articles
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Crystal Structure of Human XLF: A Twist in Nonhomologous DNA End-Joining Journal Articles
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Crystal Structure of StaL, a Glycopeptide Antibiotic Sulfotransferase from Streptomyces toyocaensis Journal Articles
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Crystal Structure of the Passenger Domain of the Escherichia coli Autotransporter EspP Journal Articles
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Detection of antibodies reacting with the antithetical duffy blood group antigens Fya and Fyb using recombinant fusion proteins containing the duffy extracellular domain Journal Articles
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Determination of the Functional Domain Organization of the Importin α Nuclear Import Factor Journal Articles
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Determination of the molecular states of the processive endocellulase Thermobifida fusca Cel9A during crystalline cellulose depolymerization Journal Articles
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Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors Journal Articles
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Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division Journal Articles
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Domain−Domain Interactions in the Aminoglycoside Antibiotic Resistance Enzyme AAC(6‘)-APH(2‘ ‘) Journal Articles
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During Apoptosis Bcl-2 Changes Membrane Topology at Both the Endoplasmic Reticulum and Mitochondria Journal Articles
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Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains Journal Articles
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Dynamics of the Fragment of Thrombomodulin Containing the Fourth and Fifth Epidermal Growth Factor-like Domains Correlate with Function Journal Articles
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Dynamin Interacts with Members of the Sumoylation Machinery Journal Articles
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Effect of receptor dimerization on membrane lipid raft structure continuously quantified on single cells by camera based fluorescence correlation spectroscopy. Journal Articles
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Effects of Cu Ions and Explicit Water Molecules on the Copper Binding Domain of Amyloid Precursor Protein APP(131–189): A Molecular Dynamics Study Journal Articles
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Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors Journal Articles
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Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP Journal Articles
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Evaluation of the Calmodulin‐SOX9 Interaction by “Magnetic Fishing” Coupled to Mass Spectrometry Journal Articles
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Evidence That Both Exosites on Thrombin Participate in Its High Affinity Interaction with Fibrin Journal Articles
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Evidence for Dual Binding Sites for 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) in Insect Sodium Channels Journal Articles
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Factor VII Deficiency Caused by a Structural Variant N57D of the First Epidermal Growth Factor Domain Journal Articles
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FuncPatch: a web server for the fast Bayesian inference of conserved functional patches in protein 3D structures Journal Articles
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Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis. Journal Articles
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Gauging a Hydrocarbon Ruler by an Intrinsic Exciton Probe Journal Articles
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Genetic identification of effectors downstream of Neu (ErbB-2) autophosphorylation sites in a Drosophila model Journal Articles
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Giardia lamblia RNA Polymerase II Journal Articles
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Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5 Journal Articles
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Homology Models of μ-Opioid Receptor with Organic and Inorganic Cations at Conserved Aspartates in the Second and Third Transmembrane Domains Journal Articles
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Horizontal Gene Transfer Contributed to the Evolution of Extracellular Surface Structures: The Freshwater Polyp Hydra Is Covered by a Complex Fibrous Cuticle Containing Glycosaminoglycans and Proteins of the PPOD and SWT (Sweet Tooth) Families Journal Articles
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Host Cell Factor-1 and E2F4 Interact Via Multiple Determinants in Each Protein Journal Articles
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Human platelets contain forms of factor V in disulfide-linkage with multimerin Journal Articles
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Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity Journal Articles
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Idarucizumab Journal Articles
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Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton Journal Articles
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Identification of Regions in HIV-1 Nef Required for Efficient Downregulation of Cell Surface CD4 Journal Articles
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Identification of a Karyopherin β1/β2 Proline-Tyrosine Nuclear Localization Signal in Huntingtin Protein Journal Articles
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Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides Journal Articles
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Identification of an Expressed Truncated Form of CD200, CD200tr, which is a Physiologic Antagonist of CD200-Induced Suppression Journal Articles
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Identification of the Binding Site of Brucella VirB8 Interaction Inhibitors Journal Articles
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Identification of the MMRN1 Binding Region within the C2 Domain of Human Factor V Journal Articles
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In Silico Activation of KcsA K+ Channel by Lateral Forces Applied to the C-Termini of Inner Helices Journal Articles
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Inferring sequence regions under functional divergence in duplicate genes Journal Articles
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Insertion of a Structural Domain of Interleukin (IL)-1β Confers Agonist Activity to the IL-1 Receptor Antagonist Journal Articles
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Insights into the evolutionary origins of clostridial neurotoxins from analysis of the Clostridium botulinum strain A neurotoxin gene cluster Journal Articles
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Interaction of local anesthetics with the K+channel pore domain Journal Articles
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Interaction of the full-length Bax protein with biomimetic mitochondrial liposomes: A small-angle neutron scattering and fluorescence study Journal Articles
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Intracellular Trafficking of CD23: Differential Regulation in Humans and Mice by Both Extracellular and Intracellular Exons Journal Articles
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Isolation and Characterization of Human Monoclonal Antibodies from Individuals Infected with West Nile Virus Journal Articles
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Isolation and Characterization of XKaiso, a Transcriptional Repressor That Associates with the Catenin Xp120 in Xenopus laevis Journal Articles
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Kinetic mechanism of the GCN5-related chromosomal aminoglycoside acetyltransferase AAC(6')-Ii from Enterococcus faecium: evidence of dimer subunit cooperativity Journal Articles
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Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung Journal Articles
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Lipid A Modification Systems in Gram-Negative Bacteria Journal Articles
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Lipid Trafficking Controls Endotoxin Acylation in Outer Membranes of Escherichia coli Journal Articles
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Local Structural Preferences and Dynamics Restrictions in the Urea-Denatured State of SUMO-1: NMR Characterization Journal Articles
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Location of the multimerin 1 binding site in coagulation factor V: An update Journal Articles
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Long Range Communication between Exosites 1 and 2 Modulates Thrombin Function Journal Articles
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Malic Enzyme Cofactor and Domain Requirements for Symbiotic N
2
Fixation by
Sinorhizobium meliloti Journal Articles
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Mapping the Interactions between the Alzheimer’s Aβ-Peptide and Human Serum Albumin beyond Domain Resolution Journal Articles
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Measurement of State-Specific Association Constants in Allosteric Sensors through Molecular Stapling and NMR Journal Articles
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Mechanism of action of the novel plasma membrane Ca2+-pump inhibitor caloxin Journal Articles
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Mechanism of cAMP Partial Agonism in Protein Kinase G (PKG) Journal Articles
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Menin: The Protein Behind the MEN1 Syndrome Journal Articles
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Modeling P-Loops Domain of Sodium Channel: Homology with Potassium Channels and Interaction with Ligands Journal Articles
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Molecular Characterization of Chinese Hamster Cells Mutants Affected in Adenosine Kinase and Showing Novel Genetic and Biochemical Characteristics Journal Articles
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Molecular cloning, localization and characterization of a 40‐kDa catecholamine‐regulated protein Journal Articles
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Multiple histidines in the periplasmic domain of the Salmonella enterica sensor kinase SsrA enhance signaling in response to extracellular acidification Journal Articles
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Mutagenesis and peptide analysis of the DRY motif in the α2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors Journal Articles
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Mutational analysis of Salmonella translocated effector members SifA and SopD2 reveals domains implicated in translocation, subcellular localization and function Journal Articles
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NMR Structures Reveal How Oxidation Inactivates Thrombomodulin Journal Articles
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Nrf2b, Novel Zebrafish Paralog of Oxidant-responsive Transcription Factor NF-E2-related Factor 2 (NRF2) Journal Articles
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Nuclear import of the BTB/POZ transcriptional regulator Kaiso Journal Articles
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Nuclear trafficking of the POZ-ZF protein Znf131 Journal Articles
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Overlapping spectra of SMAD4 mutations in juvenile polyposis (JP) and JP–HHT syndrome Journal Articles
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PDLIM7 is a novel target of the ubiquitin ligase Nedd4-1 in skeletal muscle Journal Articles
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PGC‐1α gene expression is down‐regulated by Akt‐mediated phosphorylation and nuclear exclusion of FoxO1 in insulin‐stimulated skeletal muscle Journal Articles
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PelA Deacetylase Activity Is Required for Pel Polysaccharide Synthesis in Pseudomonas aeruginosa Journal Articles
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Periplasmic Domains of Pseudomonas aeruginosa PilN and PilO Form a Stable Heterodimeric Complex Journal Articles
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Pervasive Cryptic Epistasis in Molecular Evolution Journal Articles
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Phylogenetic Gaussian Process Model for the Inference of Functionally Important Regions in Protein Tertiary Structures Journal Articles
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Possible Roles of Exceptionally Conserved Residues around the Selectivity Filters of Sodium and Calcium Channels Journal Articles
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Prediction of homoprotein and heteroprotein complexes by protein docking and template‐based modeling: A CASP‐CAPRI experiment Journal Articles
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Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53 Journal Articles
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Pseudomonas aeruginosa Minor Pilins Prime Type IVa Pilus Assembly and Promote Surface Display of the PilY1 Adhesin Journal Articles
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Purification of Plant-Derived Antibodies through Direct Immobilization of Affinity Ligands on Cellulose Journal Articles
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Re-Evaluation of a Bacterial Antifreeze Protein as an Adhesin with Ice-Binding Activity Journal Articles
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Recombinant albumins containing additional peptide sequences smaller than barbourin retain the ability of barbourin-albumin to inhibit platelet aggregation Journal Articles
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Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain Journal Articles
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Repellent Signaling by Slit Requires the Leucine-Rich Repeats Journal Articles
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Rifampin phosphotransferase is an unusual antibiotic resistance kinase Journal Articles
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Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC) Journal Articles
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Role of the Hydrophobic Segment of Diacylglycerol Kinase ε Journal Articles
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Role of third extracellular domain of plasma membrane Ca2+–Mg2+-ATPase based on the novel inhibitor caloxin 3A1 Journal Articles
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Role of α-Helical Coiled-coil Interactions in Receptor Dimerization, Signaling, and Adaptation during Bacterial Chemotaxis Journal Articles
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Rtt107 Is Required for Recruitment of the SMC5/6 Complex to DNA Double Strand Breaks Journal Articles
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SIPL1-facilitated PTEN ubiquitination contributes to its association with PTEN Journal Articles
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Selective binding of C-6 OH sulfated hyaluronic acid to the angiogenic isoform of VEGF165 Journal Articles
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Smad7 Binds to Smurf2 to Form an E3 Ubiquitin Ligase that Targets the TGFβ Receptor for Degradation Journal Articles
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Spatial structure of the novel light-sensitive photoprotein berovin from the ctenophore Beroe abyssicola in the Ca2+-loaded apoprotein conformation state Journal Articles
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Spontaneously Forming Ellipsoidal Phospholipid Unilamellar Vesicles and Their Interactions with Helical Domains of Saposin C Journal Articles
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Starch chain interactions within the amorphous and crystalline domains of pulse starches during heat-moisture treatment at different temperatures and their impact on physicochemical properties Journal Articles
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State-dependent inter-repeat contacts of exceptionally conserved asparagines in the inner helices of sodium and calcium channels Journal Articles
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Stoichiometry and Affinity of the Human Serum Albumin-Alzheimer's Aβ Peptide Interactions Journal Articles
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Structural Characterization of a Novel Chlamydia pneumoniae Type III Secretion-Associated Protein, Cpn0803 Journal Articles
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Structural Model for Phenylalkylamine Binding to L-type Calcium Channels Journal Articles
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Structural and Functional Interaction between the Human DNA Repair Proteins DNA Ligase IV and XRCC4 Journal Articles
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Structural and phylogenetic analysis of a conserved actinobacteria-specific protein (ASP1; SCO1997) from Streptomyces coelicolor Journal Articles
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Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase Journal Articles
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Structure and Function of APH(4)-Ia, a Hygromycin B Resistance Enzyme Journal Articles
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Structure and Protein-Protein Interaction Studies on
Chlamydia trachomatis
Protein CT670 (YscO Homolog) Journal Articles
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Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria Journal Articles
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Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases Journal Articles
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Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production in Pseudomonas aeruginosa Journal Articles
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Sweet Taste in Man: A Review Journal Articles
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Synthesis and biological characterisation of a series of iberiotoxin analogues Journal Articles
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TDAG51 Is Induced by Homocysteine, Promotes Detachment-mediated Programmed Cell Death, and Contributes to the Development of Atherosclerosis in Hyperhomocysteinemia Journal Articles
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Talin is required to position and expand the luminal domain of the Drosophila heart tube Journal Articles
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The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR Journal Articles
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The BH3 domain of BAD fused to the Antennapedia peptide induces apoptosis via its alpha helical structure and independent of Bcl-2 Journal Articles
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The Human Enhancer Blocker CTC-binding Factor Interacts with the Transcription Factor Kaiso Journal Articles
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The Lectin-like Domain of Thrombomodulin Confers Protection from Neutrophil-mediated Tissue Damage by Suppressing Adhesion Molecule Expression via Nuclear Factor κB and Mitogen-activated Protein Kinase Pathways Journal Articles
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The Novel Catenin p120casBinds Classical Cadherins and Induces an Unusual Morphological Phenotype in NIH3T3 Fibroblasts Journal Articles
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The Nucleotide-Binding Domain and Leucine-Rich Repeat Protein–3 Inflammasome Is Not Activated in Airway Smooth Muscle Upon Toll-Like Receptor–2 Ligation Journal Articles
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The Platform Protein Is Essential for Type IV Pilus Biogenesis Journal Articles
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The Projection Analysis of NMR Chemical Shifts Reveals Extended EPAC Autoinhibition Determinants Journal Articles
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The Role of Palmitoylation for Protein Recruitment to the Inner Membrane Complex of the Malaria Parasite Journal Articles
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The Roles of Selected Arginine and Lysine Residues of TAFI (Pro-CPU) in Its Activation to TAFIa by the Thrombin-Thrombomodulin Complex Journal Articles
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The Structure- and Metal-dependent Activity of Escherichia coli PgaB Provides Insight into the Partial De-N-acetylation of Poly-β-1,6-N-acetyl-d-glucosamine Journal Articles
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The Transactivation Function of the Pea3 Subfamily Ets Transcription Factors Is Regulated by Sumoylation Journal Articles
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The cDNA Sequence of Human Endothelial Cell Multimerin Journal Articles
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The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand Journal Articles
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The cytoplasmic domain is critical to the tumor suppressor activity of TSLC1 in non-small cell lung cancer. Journal Articles
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The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal Journal Articles
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The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4 Journal Articles
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The structure of the apo cAMP‐binding domain of HCN4 – a stepping stone toward understanding the cAMP‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels Journal Articles
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Thyroglobulin type‐1 domain protease inhibitors exhibit specific expression in the cortical ooplasm of vitellogenic rainbow trout oocytes Journal Articles
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Type IV Secretion System Core Component VirB8 from Brucella Binds to the Globular Domain of VirB5 and to a Periplasmic Domain of VirB6 Journal Articles
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Tyrosine 740 Phosphorylation of Discoidin Domain Receptor 2 by Src Stimulates Intramolecular Autophosphorylation and Shc Signaling Complex Formation Journal Articles
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Using chemical exchange to assign non-covalent protein complexes in slow exchange with the free state: Enhanced resolution and efficient signal editing Journal Articles
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Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface Journal Articles
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XPF with mutations in its conserved nuclease domain is defective in DNA repair but functions in TRF2-mediated telomere shortening Journal Articles
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c-Jun Homodimers Can Function as a Context-Specific Coactivator Journal Articles
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cAMP activation of PKA defines an ancient signaling mechanism Journal Articles
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p73 and p63: Why Do We Still Need Them? Journal Articles
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von Willebrand Factor: Form for Function Journal Articles