Journal article
Inferring sequence regions under functional divergence in duplicate genes
Abstract
MOTIVATION: A number of statistical phylogenetic methods have been proposed to identify type-I functional divergence in duplicate genes by detecting heterogeneous substitution rates in phylogenetic trees. A common disadvantage of the existing methods is that autocorrelation of substitution rates along sequences is not modeled. This reduces the power of existing methods to identify regions under functional divergence.
RESULTS: We design a …
Authors
Huang Y-F; Golding GB
Journal
Bioinformatics, Vol. 28, No. 2, pp. 176–183
Publisher
Oxford University Press (OUP)
Publication Date
January 15, 2012
DOI
10.1093/bioinformatics/btr635
ISSN
1367-4803