Journal article
An atypical proprotein convertase in Giardia lamblia differentiation
Abstract
Proteolytic activity is important in the lifecycles of parasites and their interactions with hosts. Cysteine proteases have been best studied in Giardia, but other protease classes have been implicated in growth and/or differentiation. In this study, we employed bioinformatics to reveal the complete set of putative proteases in the Giardia genome. We identified 73 peptidase homologs distributed over 5 catalytic classes in the genome. Serial …
Authors
Davids BJ; Gilbert MA; Liu Q; Reiner DS; Smith AJ; Lauwaet T; Lee C; McArthur AG; Gillin FD
Journal
Molecular and Biochemical Parasitology, Vol. 175, No. 2, pp. 169–180
Publisher
Elsevier
Publication Date
February 2011
DOI
10.1016/j.molbiopara.2010.11.008
ISSN
0166-6851