Journal article
Role of the Hydrophobic Segment of Diacylglycerol Kinase ε †
Abstract
Diacylglycerol kinase epsilon (DGKepsilon) is unique among mammalian DGK isoforms in having a segment of hydrophobic amino acids. We have evaluated the contributions of this segment to the membrane interactions and functions of this protein. To test the role of the hydrophobic segment, we have compared the properties of DGKepsilon with those of a truncated form of the protein (DGKDeltaepsilon) lacking the 40 N-terminal amino acids, which …
Authors
Dicu AO; Topham MK; Ottaway L; Epand RM
Journal
Biochemistry, Vol. 46, No. 20, pp. 6109–6117
Publisher
American Chemical Society (ACS)
Publication Date
May 1, 2007
DOI
10.1021/bi6024726
ISSN
0006-2960