CD8-Positive T-Lymphocytes Concept

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• A Human Type 5 Adenovirus–Based Tuberculosis Vaccine Induces Robust T Cell Responses in Humans Despite Preexisting Anti-Adenovirus Immunity  Journal Articles
• A Lymphotoxin/Type I IFN Axis Programs CD8+ T Cells To Infiltrate a Self-Tissue and Propagate Immunopathology  Journal Articles
• A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8+ T cells  Journal Articles
• A Switch in Costimulation from CD28 to 4-1BB during Primary versus Secondary CD8 T Cell Response to Influenza In Vivo  Journal Articles
• A mouse GM-CSF receptor antibody attenuates neutrophilia in mice exposed to cigarette smoke  Journal Articles
• A prime/boost vaccine platform efficiently identifies CD27 agonism and depletion of myeloid-derived suppressor cells as therapies that rationally combine with checkpoint blockade in ovarian cancer  Journal Articles
• ATM deficiency disrupts Tcra locus integrity and the maturation of CD4+CD8+ thymocytes  Journal Articles
• Activation of CD8 T Cells by Mycobacterial Vaccination Protects against Pulmonary Tuberculosis in the Absence of CD4 T Cells  Journal Articles
• Adaptive Antiviral Immunity Is a Determinant of the Therapeutic Success of Oncolytic Virotherapy  Journal Articles
• Adaptive Resistance to Cancer Immunotherapy  Journal Articles
• Adenovector-mediated gene delivery of interleukin-2 in metastatic breast cancer and melanoma: results of a phase 1 clinical trial  Journal Articles
• Adenoviral Vectors Expressing Lymphotactin and Interleukin 2 or Lymphotactin and Interleukin 12 Synergize to Facilitate Tumor Regression in Murine Breast Cancer Models  Journal Articles
• Adenoviral-Mediated Gene Transfer of Lymphotactin to the Lungs of Mice and Rats Results in Infiltration and Direct Accumulation of CD4⁺, CD8⁺, and NK Cells  Journal Articles
• Antigen Specificity Acquisition of Adoptive CD4+ Regulatory T Cells via Acquired Peptide-MHC Class I Complexes  Journal Articles
• Autoimmune VariantPTPN22C1858T Is Associated With Impaired Responses to Influenza Vaccination  Journal Articles
• Behavioral heterogeneity in an animal model of neuropsychiatric lupus  Journal Articles
• Biological sex, not reproductive cycle, influences peripheral blood immune cell prevalence in mice  Journal Articles
• Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity  Journal Articles
• CD8+ T cell-mediated suppression of HIV long terminal repeat-driven gene expression is not associated with improved clinical status  Journal Articles
• CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells  Journal Articles
• CD8+ T-cell-mediated suppression of HIV-1 long terminal repeat-driven gene expression is not modulated by the CC chemokines RANTES, macrophage inflammatory protein (MIP)-1α and MIP-1β  Journal Articles
• CD8+CD28−CD127loCD39+ regulatory T-cell expansion: A new possible pathogenic mechanism for HIV infection?  Journal Articles
• CXCR3 Signaling Is Required for Restricted Homing of Parenteral Tuberculosis Vaccine–Induced T Cells to Both the Lung Parenchyma and Airway  Journal Articles
• CXCR6 by increasing retention of memory CD8⁺ T cells in the ovarian tumor microenvironment promotes immunosurveillance and control of ovarian cancer  Journal Articles
• Changes in interferon‐γ production following specific allergen immunotherapy: biology vs methodology  Journal Articles
• Chronic Immune Activation and CD4+ T Cell Lymphopenia in Healthy African Individuals: Perspectives for SARS-CoV-2 Vaccine Efficacy  Journal Articles
• Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice  Journal Articles
• Combined CXC chemokine and interleukin-12 gene transfer enhances antitumor immunity  Journal Articles
• Combined mTOR Inhibition and OX40 Agonism Enhances CD8+ T Cell Memory and Protective Immunity Produced by Recombinant Adenovirus Vaccines  Journal Articles
• Combined mTOR inhibition and OX40 agonism enhances CD8(+) T cell memory and protective immunity produced by recombinant adenovirus vaccines.  Journal Articles
• Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy  Journal Articles
• Critical Negative Regulation of Type 1 T Cell Immunity and Immunopathology by Signaling Adaptor DAP12 during Intracellular Infection  Journal Articles
• Critical Role of Natural Killer Cells in Lung Immunopathology During Influenza Infection in Mice  Journal Articles
• Deciphering the Immunomodulatory Capacity of Oncolytic Vaccinia Virus to Enhance the Immune Response to Breast Cancer  Journal Articles
• Delivery of viral-vectored vaccines by B cells represents a novel strategy to accelerate CD8+ T-cell recall responses  Journal Articles
• DetailedAnalysis of the CD8 ⁺ T-Cell Response followingAdenovirusVaccination  Journal Articles
• Development of Cell-Based Tuberculosis Vaccines: Genetically Modified Dendritic Cell Vaccine Is a Much More Potent Activator of CD4 and CD8 T Cells Than Peptide- or Protein-Loaded Counterparts  Journal Articles
• Different Profile of Interleukin‐10 Production in Circulating T Cells from Atopic Asthmatics Compared with Healthy Subjects  Journal Articles
• Different profiles of T-cell IFN-γ and IL-12 in allergen-induced early and dual responders with asthma  Journal Articles
• Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model  Journal Articles
• Effects of inhaled ciclesonide on circulating T‐helper type 1/T‐helper type 2 cells in atopic asthmatics after allergen challenge  Journal Articles
• Electroporation Enables Plasmid Vaccines to Elicit CD8+ T Cell Responses in the Absence of CD4+ T Cells  Journal Articles
• Elevated Frequencies of Self-reactive CD8+ T Cells following Immunization with a Xenoantigen Are Due to the Presence of a Heteroclitic CD4+ T-Cell Helper Epitope  Journal Articles
• Enhanced HER-2/neu-specific antitumor immunity by cotransduction of mouse dendritic cells with two genes encoding HER-2/neu and alpha tumor necrosis factor  Journal Articles
• Enhancement of Antituberculosis Immunity in a Humanized Model System by a Novel Virus-Vectored Respiratory Mucosal Vaccine  Journal Articles
• Estradiol Enhances Antiviral CD4⁺Tissue-Resident Memory T Cell Responses following Mucosal Herpes Simplex Virus 2 Vaccination through an IL-17-Mediated Pathway  Journal Articles
• Expression and role of VLA-1 in resident memory CD8 T cell responses to respiratory mucosal viral-vectored immunization against tuberculosis  Journal Articles
• Expression of IL-4 and IL-5 mRNA and protein product by CD4+ and CD8+ T cells, eosinophils, and mast cells in bronchial biopsies obtained from atopic and nonatopic (intrinsic) asthmatics.  Journal Articles
• FoxP3 overexpression and CD1a+ and CD3+ depletion in anal tissue as possible mechanisms for increased risk of human papillomavirus-related anal carcinoma in HIV infection  Journal Articles
• GM-CSF transgene expression in the airway allows aerosolized ovalbumin to induce allergic sensitization in mice.  Journal Articles
• Gamma Interferon Responses of CD4 and CD8 T-Cell Subsets Are Quantitatively Different and Independent of Each Other during PulmonaryMycobacterium bovisBCG Infection  Journal Articles
• Generation of experimental allergic airways inflammation in the absence of draining lymph nodes  Journal Articles
• Genetically modified dendritic cells prime autoreactive T cells through a pathway independent of CD40L and interleukin 12: implications for cancer vaccines.  Journal Articles
• HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants  Journal Articles
• HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity  Journal Articles
• HIV-1 Subtype C Gag-Specific T-Cell Responses in Relation to Human Leukocyte Antigens in a Diverse Population of HIV-Infected Ethiopians  Journal Articles
• HLA Variation and SARS-CoV-2 Specific Antibody Response  Journal Articles
• Herpes simplex virus-2 in the genital mucosa  Journal Articles
• Heterologous Boosting of Recombinant Adenoviral Prime Immunization With a Novel Vesicular Stomatitis Virus–vectored Tuberculosis Vaccine  Journal Articles
• IL-10 production in circulating T cells differs between allergen-induced isolated early and dual asthmatic responders  Journal Articles
• IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells  Journal Articles
• IL-15 has innate anti-tumor activity independent of NK and CD8 T cells  Journal Articles
• Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells  Journal Articles
• Immune recovery in HIV-1 infected patients with sustained viral suppression under long-term antiretroviral therapy in Ethiopia  Journal Articles
• Immune response to changes in training intensity and volume in runners  Journal Articles
• Immunity Against Heterosubtypic Influenza Virus Induced By Adenovirus And MVA Expressing Nucleoprotein And Matrix Protein-1  Journal Articles
• Immunization With a Bivalent Adenovirus-vectored Tuberculosis Vaccine Provides Markedly Improved Protection Over Its Monovalent Counterpart Against Pulmonary Tuberculosis  Journal Articles
• Immunogenic HSV-mediated Oncolysis Shapes the Antitumor Immune Response and Contributes to Therapeutic Efficacy  Journal Articles
• Immunohistochemical Markers in the Diagnosis of Calcifying Pseudoneoplasm of the Neuraxis  Journal Articles
• Immunomodulatory drugs have divergent effects on humoral and cellular immune responses to SARS-CoV-2 vaccination in people living with rheumatoid arthritis  Journal Articles
• Immunopathology in influenza virus infection: Uncoupling the friend from foe  Journal Articles
• Immunophenotyping of blood lymphocytes at birth, during childhood, and during adulthood in HIV-1-uninfected Ethiopians  Journal Articles
• Immunosenescence in the nursing home elderly  Journal Articles
• Immunotherapy-induced CD8+ T Cells Instigate Immune Suppression in the Tumor  Journal Articles
• In vitro analysis of the herbal compound Essiac.  Journal Articles
• Increased CD4 : CD8 ratio normalization with implementation of current ART management guidelines  Journal Articles
• Increased cytotoxic potential of CD8⁺ T cells in immune thrombocytopenia  Journal Articles
• Induced sputum, bronchoalveolar lavage and blood from mild asthmatics: inflammatory cells, lymphocyte subsets and soluble markers compared  Journal Articles
• Induction and abrogation of LACK reactive cells in the evolution of human leishmaniasis  Journal Articles
• Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity  Journal Articles
• Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12  Journal Articles
• Influence of the Estrous Cycle on the Presence and Distribution of Immune Cells in the Rat Reproductive Tract  Conferences
• Influenza A Virus Specific T Cell Immunity in Humans during Aging  Journal Articles
• Inhalation of a harmless antigen (ovalbumin) elicits immune activation but divergent immunoglobulin and cytokine activities in mice  Journal Articles
• Inhibition of Immunoprotective CD8+T Cells as a Basis for Stress-Triggered Substance P-Mediated Abortion in Mice  Journal Articles
• Interleukin-18 expression, CD8+ T cells, and eosinophils in lungs of nonsmokers with fatal asthma  Journal Articles
• Intraindividual Variability and the Effect of Acute Illness on Immune Senescence Markers  Conferences
• Intramuscular immunization with a monogenic plasmid DNA tuberculosis vaccine: Enhanced immunogenicity by electroporation and co-expression of GM-CSF transgene  Journal Articles
• Intranasal Boosting with an Adenovirus-Vectored Vaccine Markedly Enhances Protection by Parenteral Mycobacterium bovis BCG Immunization against Pulmonary Tuberculosis  Journal Articles
• JC Virus-DNA Detection Is Associated with CD8 Effector Accumulation in Peripheral Blood of Patients with Multiple Sclerosis under Natalizumab Treatment, Independently from JC Virus Serostatus  Journal Articles
• Ketogenesis-generated β-hydroxybutyrate is an epigenetic regulator of CD8+ T-cell memory development  Journal Articles
• Maraba Virus as a Potent Oncolytic Vaccine Vector  Journal Articles
• Measles Vaccines Designed for Enhanced CD8+ T Cell Activation  Journal Articles
• Mechanisms of Mucosal and Parenteral Tuberculosis Vaccinations: Adenoviral-Based Mucosal Immunization Preferentially Elicits Sustained Accumulation of Immune Protective CD4 and CD8 T Cells within the Airway Lumen  Journal Articles
• Mesenchymal Stromal Cells but Not Cardiac Fibroblasts Exert Beneficial Systemic Immunomodulatory Effects in Experimental Myocarditis  Journal Articles
• Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties  Journal Articles
• Mucosal Luminal Manipulation of T Cell Geography Switches on Protective Efficacy by Otherwise Ineffective Parenteral Genetic Immunization  Journal Articles
• Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells  Journal Articles
• Murine Airway Luminal Antituberculosis Memory CD8 T Cells by Mucosal Immunization Are Maintained Via Antigen-Driven In Situ Proliferation, Independent of Peripheral T Cell Recruitment  Journal Articles
• On the Role of CD4+ T Cells in the CD8+ T-Cell Response Elicited by Recombinant Adenovirus Vaccines  Journal Articles
• Oncolytic Maraba virus armed with tumor antigen boosts vaccine priming and reveals diverse therapeutic response patterns when combined with checkpoint blockade in ovarian cancer  Journal Articles
• Optimizing vaccine-induced CD8⁺T-cell immunity: focus on recombinant adenovirus vectors  Journal Articles
• Persistence of Transgene Expression Influences CD8⁺T-Cell Expansion and Maintenance following Immunization with Recombinant Adenovirus  Journal Articles
• Persistent infection with Crohn’s disease-associated adherent-invasive Escherichia coli leads to chronic inflammation and intestinal fibrosis  Journal Articles
• Pre-existing immunity against swine-origin H1N1 influenza viruses in the general human population  Journal Articles
• Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B  Journal Articles
• Preferential Proliferation and Differentiation of Double-Positive Thymocytes into CD8+ Single-Positive Thymocytes in a Novel Cell Culture Medium  Journal Articles
• Primary HIV-1 Subtype C Infection in Ethiopia  Journal Articles
• Privileged Antigen Presentation in Splenic B Cell Follicles Maximizes T Cell Responses in Prime-Boost Vaccination  Journal Articles
• Protection by CD4 or CD8 T Cells against PulmonaryMycobacterium bovisBacillus Calmette-Guérin Infection  Journal Articles
• Pyroptosis activates conventional type I dendritic cells to mediate the priming of highly functional anticancer T cells  Journal Articles
• RANTES Production by T Cells and CD8‐Mediated Inhibition of Human Immunodeficiency Virus Gene Expression before Initiation of Potent Antiretroviral Therapy Predict Sustained Suppression of Viral Replication  Journal Articles
• Radiation-Induced Lymphocyte Apoptosis to Predict Radiation Therapy Late Toxicity in Prostate Cancer Patients  Journal Articles
• Recombinant Adenovirus Vaccines Can Successfully Elicit CD8+ T Cell Immunity under Conditions of Extreme Leukopenia  Journal Articles
• Respiratory mucosal immunization with adenovirus gene transfer vector induces helper CD4 T cell‐independent protective immunity  Journal Articles
• Role of B Cells in Mucosal Vaccine–Induced Protective CD8+ T Cell Immunity against Pulmonary Tuberculosis  Journal Articles
• Role of incidental and/or cured intestinal parasitic infections on profile of CD4+ and CD8+ T cell subsets and activation status in HIV-1 infected and uninfected adult Ethiopians  Journal Articles
• Single Mucosal, but Not Parenteral, Immunization with Recombinant Adenoviral-Based Vaccine Provides Potent Protection from Pulmonary Tuberculosis  Journal Articles
• Spinal calcifying pseudoneoplasm of the neuraxis (CAPNON) associated with facet joint pathologies: CAPNON diagnostic and pathogenic insights  Journal Articles
• Sputum T lymphocytes in asthma, COPD and healthy subjects have the phenotype of activated intraepithelial T cells (CD69+ CD103+)  Journal Articles
• Suppression of NK and CD8+ T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease  Journal Articles
• Surface Phenotype and Functionality of WNV Specific T Cells Differ with Age and Disease Severity  Journal Articles
• Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence  Journal Articles
• T Cell-Derived Suppressive Activity: Evidence of Autocrine Noncytolytic Control of HIV Type 1 Transcription and Replication  Journal Articles
• T cell–mediated autoimmunity in immune thrombocytopenia  Journal Articles
• T-cell immunity generated by recombinant adenovirus vaccines  Journal Articles
• T-cell-mediated inflammation does not contribute to the maintenance of airway dysfunction in mice  Journal Articles
• Taurocholic acid inhibits the response to interferon-α therapy in patients with HBeAg-positive chronic hepatitis B by impairing CD8+ T and NK cell function.  Journal Articles
• The CD8+ T Cell Population Elicited by Recombinant Adenovirus Displays a Novel Partially Exhausted Phenotype Associated with Prolonged Antigen Presentation That Nonetheless Provides Long-Term Immunity  Journal Articles
• The Effect of Adding a Surfeit of Autologous CD8⁺T Cells to SCID Mice after Secondary Rexenografts of Graves' Thyroid Tissue  Journal Articles
• The Hayflick Limit May Determine the Effective Clonal Diversity of Naive T Cells  Journal Articles
• The Memory T Cell Response to West Nile Virus in Symptomatic Humans following Natural Infection Is Not Influenced by Age and Is Dominated by a Restricted Set of CD8+ T Cell Epitopes  Journal Articles
• The Polyfunctionality of Human Memory CD8+ T Cells Elicited by Acute and Chronic Virus Infections Is Not Influenced by Age  Journal Articles
• The Soluble Tachyzoite Antigen of Toxoplasma gondii Has a Protective Effect on Mouse Allografts  Journal Articles
• The magnitude of the CD8+ T cell response produced by recombinant virus vectors is a function of both the antigen and the vector  Journal Articles
• Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Nonmetastatic Castrate-Resistant Prostate Cancer  Journal Articles
• Transcriptional programs of neoantigen-specific TIL in anti-PD-1-treated lung cancers  Journal Articles
• Tumor Protection Following Vaccination With Low Doses of Lentivirally Transduced DCs Expressing the Self-antigen erbB2  Journal Articles
• T‐Cell Phenotypes Predictive of Frailty and Mortality in Elderly Nursing Home Residents  Journal Articles
• Vaccination-Induced Autoimmune Vitiligo Is a Consequence of Secondary Trauma to the Skin  Journal Articles
• Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus  Journal Articles
• [Ad hTRP2 - mediated immunity against melanoma is enhanced by dendritic cells pulsed with peptide].  Journal Articles
• [Dysregulated proportion of intrahepatic Treg cells and Th17 along with CD8+ T lymphocytes drives disease progression after kasai biliary atresia surgery].  Journal Articles
• cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory  Journal Articles