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Biological sex, not reproductive cycle, influences...
Journal article

Biological sex, not reproductive cycle, influences peripheral blood immune cell prevalence in mice

Abstract

KEY POINTS: Traditionally the female sex, compared with the male sex, has been perceived as having greater variability in many physiological traits, including within the immune system. We investigated effects of biological sex and the female reproductive cycle on numbers of circulating leukocytes in C57BL/6J mice. We show that biological sex, but not female reproductive cyclicity, has a significant effect on peripheral blood immune cell …

Authors

Breznik JA; Schulz C; Ma J; Sloboda DM; Bowdish DME

Journal

The Journal of Physiology, Vol. 599, No. 8, pp. 2169–2195

Publisher

Wiley

Publication Date

April 2021

DOI

10.1113/jp280637

ISSN

0022-3751