Journal article
Immunomodulatory drugs have divergent effects on humoral and cellular immune responses to SARS-CoV-2 vaccination in people living with rheumatoid arthritis
Abstract
Understanding the efficacy of SARS-CoV-2 vaccination in people on immunosuppressive drugs, including those with rheumatoid arthritis (RA), is critical for their protection. Vaccine induced protection requires antibodies, CD4+ T cells, and CD8+ T cells, but it is unclear if these are equally affected by immunomodulatory drugs. Here, we determined how humoral and cellular SARS-CoV-2 vaccination responses differed between people with RA and …
Authors
Benoit JM; Breznik JA; Ang JC; Bhakta H; Huynh A; Cowbrough B; Baker B; Heessels L; Lodhi S; Yan E
Journal
Scientific Reports, Vol. 13, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41598-023-50263-5
ISSN
2045-2322