selected scholarly activity
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chapters
- Chapter 30 Cytokine Gene Therapy in Bone Remodeling. 365-374. 2010
- Cytokine Gene Therapy in Bone Remodeling. 365-374. 2010
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conferences
- Oncostatin M induction of monocyte chemoattractant protein 1 (MCP-1) in human epidermal keratinocytes is inhibited by anti-oncostatin M receptor beta monoclonal antibody KPL-716. Journal of Investigative Dermatology. S110-S110. 2019
- IL-33 modulates lung inflammation induced by the IL-6-type (gp130) cytokine Oncostatin M. Cytokine. 113-113. 2017
- CUTANEOUS OVEREXPRESSION OF ONCOSTATIN M LEADS TO ROBUST INFLAMMATION BUT ITS EXPRESSION IS NOT NECESSARY TO INDUCE A PSORIASIS-LIKE INFLAMMATION BY TOPICAL APPLICATION OF IMIQUIMOD ON MOUSE SKIN. Cytokine. 106-106. 2016
- Il-6 Mediated Hyperpolarization Of Profibrotic Macrophages Is Dependent On Spliced Xbp1. American Journal of Respiratory and Critical Care Medicine. 2016
- Requirement Of Il-6 For Maximal M2 Macrophage Accumulation, And Growth Of Ectopically Delivered B16 Melanoma, In Mouse Lungs Upon Oncostatin M Overexpression. American Journal of Respiratory and Critical Care Medicine. 2016
- 106. Cytokine. 268-268. 2013
- 283. Cytokine. 310-310. 2013
- PS1-013. IL-6-independent stimulation of B cell activation, iBALT formation and Th2-skewed immune responses in lungs by Mouse Oncostatin M. Cytokine. 19-19. 2011
- Direct anti-cancer effect of oncostatin M on chondrosarcoma. Bone. S36-S36. 2011
- PS2-03 Overexpression of oncostatin-M in lungs induces eotaxin-2 and eosinophil accumulation in C57BL/6 but not Balb/C mice in vivo. Cytokine. 50-50. 2010
- PS2-04 Oncostatin M induces interleukin-1R1, interleukin-17 receptor a and synergistic responses to IL-1 and IL-17A ligands in mouse aortic adventitial fibroblasts. Cytokine. 50-51. 2010
- PS2-27 Bioactive oncostatin m is present in induced-sputum samples from house dust mite -sensitive asthmatic subjects. Cytokine. 56-56. 2010
- INTERLEUKIN 15 DEFICIENCY DECREASES ATHEROSCLEROSIS IN APOLIPOPROTEIN E KNOCKOUT MICE. ATHEROSCLEROSIS SUPPLEMENTS. 2009
- 118 Oncostatin-M induces accumulation of airway eosinophils and extracellular matrix through STAT6-dependent and -independent pathways. Cytokine. 264-264. 2008
- 124 Differential responses to oncostatin-M in C57BL/6 and BALB/C mice in vivo. Cytokine. 265-265. 2008
- 132 Oncostatin M induces interleukin-17 receptor a and synergistic responses to interleukin-17 in mouse aortic adventitial fibroblasts. Cytokine. 267-267. 2008
- 128 Oncostatin M-receptor Deficient Phenotype Provides Evidence that Oncostatin M is Critical for IL-4-induced Eosinophil Accumulation in Lungs In Vivo. Cytokine. 35-35. 2007
- 143 Oncostatin M Regulation of Murine Adipose-derived Mesenchymal Progenitor Cell Differentiation Involves Protein Kinase C Delta. Cytokine. 39-40. 2007
- 38 Oncostatin M in Combination with IL-4 or IL-13 Induces Synergistic Eotaxin-1 Expression Through Modulation of IL-4Rα and STAT6 in Mouse Fibroblasts. Cytokine. 11-11. 2007
- Oncostatin M: Anabolic action in bone generation. Osteoporosis International. 963-964. 2006
- Adenoviral gene transfer of interleukin-1 or TNF induces synovial inflammation in wild type and oncostatin M receptor beta deficient mice.. Arthritis and Rheumatism. S280-S280. 2003
- Adenoviral transfer of murine OncostatinM induces inflammation and bone apposition in joints of IL-1, IL-6 and TNF-α deficient mice. Arthritis Research & Therapy. 57-57. 2002
- Adenoviral expression of murine Oncostatin M induces inflammation and bone apposition in joints of IL-1, IL-6 and TNF-alpha deficient mice.. Journal of Leukocyte Biology. 92-92. 2001
- Stimulation of osteoclast differentiation in vitro by mouse Oncostatin M, leukemia inhibitory factor, cardiotrophin-1 and interleukin-6: Synergy with dexamethasone.. Journal of Bone and Mineral Research. S280-S280. 2000
- Cytokine gene transfer to the liver and regulation of the acute-phase response. CYTOKINES AND CELL HOMEOSTASIS IN THE GASTROINTESTINAL TRACT. 229-240. 2000
- Adenovector-mediated gene transfer of active transforming growth factor-beta(1) in the murine knee joint induces fibrosis and osteophyte formation.. European Cytokine Network. 498-498. 1998
- Adenovector-mediated gene transfer of active transforming growth factor-beta(1) in the murine knee joint induces fibrosis and osteophyte formation.. Arthritis and Rheumatism. S43-S43. 1998
- Intra-articular interleukin-10 gene transfer with an adenoviral vector suppresses collagen-induced arthritis. European Cytokine Network. 363-363. 1998
- Intra-articular interleukin-10 gene transfer with an adenoviral vector suppresses collagen-induced arthritis. Arthritis and Rheumatism. S96-S96. 1998
- Mouse oncostatin m regulates tissue inhibitor of metalloproteinase-1 and interleukin-6 expression by mouse synovial fibroblasts in vitro.. Arthritis and Rheumatism. S38-S38. 1998
- Overexpression of mouse oncostatin M in joints by adenovirus vector causes pannus-like alterations in synovium of mice.. Arthritis and Rheumatism. S247-S247. 1998
- Protection against cartilage damage and bone-erosion in collagen-induced arthritis by local adenoviral vector-mediated interleukin-4 expression in the mouse knee joint. European Cytokine Network. 362-362. 1998
- Protection against cartilage damage and bone-erosion in collagen-induced arthritis by local adenoviral vector-mediated interleukin-4 expression in the mouse knee joint.. Arthritis and Rheumatism. S246-S246. 1998
- Mobilization of epithelial stat-1 in response to mediators released from bacterial superantigen-activated immune cells. Gastroenterology. A1131-A1131. 1998
- Adenovirus Vectors for Cytokine Gene Expression. Annals of the New York Academy of Sciences. 282-293. 1995
- ONCOSTATIN-M INHIBITS TYPE-1 PLASMINOGEN-ACTIVATOR INHIBITOR SYNTHESIS IN CULTURE HUMAN ENDOTHELIUM. Thrombosis and Haemostasis. 1128-1128. 1995
- INTRATUMOR INJECTION OF A REC-ADENOVIRUS EXPRESSING MURINE IL-6 ATTENUATES TUMOR-GROWTH IN A TRANSGENIC BREAST-CARCINOMA MODEL. Journal of Cellular Biochemistry. 418-418. 1995
- ONCOSTATIN-M INHIBITS NEUTROPHIL INFLUX IN LPS-INDUCED ACUTE LUNG INFLAMMATION IN SPRAGUE-DAWLEY RATS. The FASEB Journal. A492-A492. 1995
- Cytokine regulation of hepatic acute phase protein expression. CYTOKINES AND THE LIVER. 164-171. 1995
- PROSTANOID ENHANCEMENT OF IL-6 PRODUCTION BY RAT PERITONEAL MAST-CELLS. Journal of Allergy and Clinical Immunology. 297-297. 1995
- ONCOSTATIN-M REGULATES CYTOKINE RELEASE FROM FIBROBLASTS BUT NOT PERIPHERAL-BLOOD MONOCYTES OR NEUTROPHILS. The FASEB Journal. A222-A222. 1994
- RECOMBINANT ADENOVIRUS-MESSENGER RANTES GENE-TRANSFER INTO B16 MOUSE MELANOMA-CELLS REDUCES TUMORIGENICITY IN-VIVO. The FASEB Journal. A201-A201. 1994
- PLATELET REACTIONS CAUSED PRIMARILY BY PLASMA SUPERNATANT. Transfusion. S62-S62. 1993
- REGULATION BY ONCOSTATIN-M (OM), IL-1 AND PGE2 OF FIBROBLAST CYTOKINE RELEASE. Journal of Immunology. A214-A214. 1993
- ANCHORAGE-INDEPENDENT GROWTH OF FIBROBLAST COLONIES FROM LINES ESTABLISHED FROM HUMAN IDIOPATHIC PULMONARY FIBROTIC TISSUE. American Review of Respiratory Disease. A158-A158. 1993
- CONSTRUCTION AND INVIVO EFFECTS OF A RECOMBINANT HUMAN ADENOVIRUS TYPE-5 EXPRESSING THE MURINE INTERLEUKIN-6 CDNA ON REPLICATION. The FASEB Journal. A1781-A1781. 1992
- EFFECT OF RHEUMATOID-ARTHRITIS SERUM (RA-SE) AND SYNOVIAL-FLUID (-SF) ON IL-8 AND GM-CSF PRODUCTION BY HUMAN SYNOVIOCYTES (SYN). The FASEB Journal. A1898-A1898. 1992
- IL-6 AND IL-6 RECEPTOR (IL-6R) EXPRESSION AND MODULATION DURING ACUTE-INFLAMMATION IN THE RAT. The FASEB Journal. A1896-A1896. 1992
- REGULATION OF TIMP EXPRESSION IN SYNOVIAL FIBROBLASTS BY PGE2 AND CYTOKINES. The FASEB Journal. A941-A941. 1992
- CYTOKINE CONTROL OF ACUTE PHASE PROTEIN EXPRESSION. CYTOKINES AND INFLAMMATION. 29-50. 1991
- INTERFERON-BETA-2 IS IDENTICAL TO HSF AND REGULATES THE FULL ACUTE PHASE PROTEIN RESPONSE IN LIVER-CELLS. Journal of Leukocyte Biology. 554-554. 1987
- MACROPHAGE DERIVED IL-1 AND HEPATOCYTE STIMULATING FACTOR (HSF) ARE DISTINCT ENTITIES THAT INDUCE ACUTE PHASE PROTEIN-SYNTHESIS. Journal of Leukocyte Biology. 274-274. 1986
- THE REGULATION OF INTRACELLULAR PH IN RAT SUPERIOR CERVICAL-GANGLION CELLS GROWN IN TISSUE-CULTURE. Journal of Physiology. P38-P38. 1986
- PURIFICATION OF HEPATOCYTE STIMULATING FACTOR FROM RAT ALVEOLAR MACROPHAGES. The FASEB Journal. 1187-1187. 1985
- Rat brain membranes have specific high-affinity binding sites for NAD. Biochemical Society Transactions. 804-805. 1984
- ALVEOLAR MACROPHAGE FACTORS MODULATE THE INVITRO RESPONSE OF LYMPHOCYTES, FIBROBLASTS AND HEPATOCYTES. Journal of Leukocyte Biology. 411-411. 1984
- THE DETECTION OF A NOVEL NEUROACTIVE MATERIAL THAT FACILITATES SYNAPTIC TRANSMISSION IN THE GUINEA-PIG HIPPOCAMPUS. Journal of Physiology. P40-P40. 1984
- IMMUNOGLOBULIN AND COMPLEMENT RECEPTORS ON NORMAL AND ACTIVATED ALVEOLAR MACROPHAGE. The FASEB Journal. 955-955. 1983
- NICOTINAMIDE ADENINE-DINUCLEOTIDE (NAD) SUPPRESSES EXCITATORY SYNAPTIC TRANSMISSION IN THE DENTATE GYRUS OF THE GUINEA-PIG. Journal of Physiology. P63-P64. 1983
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journal articles
- Overexpression of Il-6 in Bleomycin-Treated Balb/C Mice Provides a New Model of Lung Fibrosis: Transcriptomic Comparison to Human Ipf 2024
- Eosinophil-independent IL-5 levels are increased in critically ill COVID-19 patients who survive. Allergy, Asthma and Clinical Immunology. 19:58. 2023
- Biophysical and Biochemical Regulation of Cell Dynamics in Magnetically Assembled Cellular Structures. ACS Omega. 8:19976-19986. 2023
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Myeloid‐specific deletion of activating transcription factor 6 alpha increases
CD11b + macrophage subpopulations and aggravates lung fibrosis. Immunology and Cell Biology. 101:412-427. 2023 - Type I Interferon Signaling is Required for Oncostatin-M Driven Inflammatory Responses in Mouse Lung. Journal of Interferon and Cytokine Research. 42:568-579. 2022
- Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar–capillary barrier function during influenza infection. European Respiratory Journal. 60:2102049-2102049. 2022
- Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection. PLoS Pathogens. 18:e1010471-e1010471. 2022
- Benralizumab for Prednisone-Dependent Eosinophilic Asthma Associated With Novel STAT3 Loss of Function Mutation. Chest. 159:e181-e184. 2021
- IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M. Mediators of Inflammation. 2020:1-17. 2020
- Oncostatin M Induction of Monocyte Chemoattractant Protein 1 is Inhibited by Anti-oncostatin M Receptor Beta Monoclonal Antibody KPL-716. Acta Dermato-Venereologica. 100:adv00197-adv00197. 2020
- RELMα Is Induced in Airway Epithelial Cells by Oncostatin M without Requirement of STAT6 or IL-6 in Mouse Lungs In Vivo. Cells. 9:1338-1338. 2020
- Oncostatin M in the Regulation of Connective Tissue Cells and Macrophages in Pulmonary Disease. Biomedicines. 7:95-95. 2019
- IL-15 and IFN-γ signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling. Cytokine. 124:154439-154439. 2019
- Extracellular Matrix and Fibrocyte Accumulation in BALB/c Mouse Lung upon Transient Overexpression of Oncostatin M. Cells. 8:126-126. 2019
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IL ‐6 mediatesER expansion during hyperpolarization of alternatively activated macrophages. Immunology and Cell Biology. 97:203-217. 2019 -
Separate roles of
IL ‐6 and oncostatin M in mouse macrophage polarization in vitro and in vivo. Immunology and Cell Biology. 96:257-272. 2018 - Overexpression of OSM and IL-6 impacts the polarization of pro-fibrotic macrophages and the development of bleomycin-induced lung fibrosis. Scientific Reports. 7:13281. 2017
- IL-18/IL-15/IL-12 synergy induces elevated and prolonged IFN-γ production by ex vivo expanded NK cells which is not due to enhanced STAT4 activation. Molecular Immunology. 88:138-147. 2017
- Innate Immune Cytokines, Fibroblast Phenotypes, and Regulation of Extracellular Matrix in Lung. Journal of Interferon and Cytokine Research. 37:52-61. 2017
- Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth. Journal of the American Heart Association. 5:e003945. 2016
- Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod‐induced psoriasis‐like inflammation. European Journal of Immunology. 46:1737-1751. 2016
- Regulation of IL-33 by Oncostatin M in Mouse Lung Epithelial Cells. Mediators of Inflammation. 2016:1-12. 2016
- Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2+CD4+lymphocytes. American Journal of Physiology - Gastrointestinal and Liver Physiology. 309:G542-G553. 2015
- Oncostatin M regulates osteogenic differentiation of murine adipose-derived mesenchymal progenitor cells through a PKCdelta-dependent mechanism. Cell and Tissue Research. 360:309-319. 2015
- Novel function of Oncostatin M as a potent tumour‐promoting agent in lung. International Journal of Cancer. 136:831-843. 2015
- Abstract 641: Interleukin-15 Plays a Role in Atherosclerosis Through Effects on Multiple Inflammatory Cells in ApoE-/- Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 34. 2014
- Interleukin-15 Modulates Adipose Tissue by Altering Mitochondrial Mass and Activity. PLoS ONE. 9:e114799-e114799. 2014
- The Enigmatic Cytokine Oncostatin M and Roles in Disease. ISRN Dentistry. 2013:1-23. 2013
- Pulmonary Expression of Oncostatin M (OSM) Promotes Inducible BALT Formation Independently of IL-6, Despite a Role for IL-6 in OSM-Driven Pulmonary Inflammation. Journal of Immunology. 191:1453-1464. 2013
- Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells. Mediators of Inflammation. 2013:1-14. 2013
- Genetic partitioning of interleukin‐6 signalling in mice dissociates Stat3 from Smad3‐mediated lung fibrosis. EMBO Molecular Medicine. 4:939-951. 2012
- Abstract 80: Interleukin 15 Plays an Important Role in the Development of Atherosclerosis in Apolipoprotein E Knockout Mice. Arteriosclerosis, Thrombosis and Vascular Biology. 32. 2012
- IL-15 Can Signal via IL-15Rα, JNK, and NF-κB To Drive RANTES Production by Myeloid Cells. Journal of Immunology. 188:4149-4157. 2012
- Induction of Osteogenesis in Mesenchymal Stem Cells by Activated Monocytes/Macrophages Depends on Oncostatin M Signaling. Stem Cells. 30:762-772. 2012
- Direct anti‐cancer effect of oncostatin M on chondrosarcoma. International Journal of Cancer. 128:1822-1835. 2011
- A Mouse Model of Airway Disease: Oncostatin M-Induced Pulmonary Eosinophilia, Goblet Cell Hyperplasia, and Airway Hyperresponsiveness Are STAT6 Dependent, and Interstitial Pulmonary Fibrosis Is STAT6 Independent. Journal of Immunology. 186:1107-1118. 2011
- Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1. Experimental Cell Research. 315:3486-3499. 2009
- Abstract: P643 INTERLEUKIN 15 DEFICIENCY DECREASES ATHEROSCLEROSIS IN APOLIPOPROTEIN E KNOCKOUT MICE. Atherosclerosis Plus. 10:e829-e829. 2009
- Role of STAT6 and SMAD2 in a model of chronic allergen exposure: a mouse strain comparison study. Clinical and Experimental Allergy. 39:147-158. 2009
- Poster 136: Measurement Properties of Circulating Interleukin-6 and Oncostatin-M For Quantifying Musculoskeletal Injury. Archives of Physical Medicine and Rehabilitation. 89:e63-e64. 2008
- Poster 146: Predictors of Hospital Length of Stay Following Knee Replacement Surgery. Archives of Physical Medicine and Rehabilitation. 89:e67-e67. 2008
- Oncostatin M Induces Bone Loss and Sensitizes Rat Osteosarcoma to the Antitumor Effect of MidostaurinIn vivo. Clinical Cancer Research. 14:5400-5409. 2008
- Oncostatin M induction of eotaxin-1 expression requires the convergence of PI3′K and ERK1/2 MAPK signal transduction pathways. Cellular Signalling. 20:1142-1150. 2008
- Poster 110: Comparison of Serum Interleukin-6 and Creatine Kinase Concentrations Following Lumbar Decompression Surgery. Archives of Physical Medicine and Rehabilitation. 88:E40-E40. 2007
- Oncostatin M-Induced IL-6 Expression in Murine Fibroblasts Requires the Activation of Protein Kinase Cδ. Journal of Immunology. 177:8740-8747. 2006
- Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: Implications for cartilage degradation in arthritis. Arthritis and Rheumatism. 54:3244-3253. 2006
- Oncostatin-M Up-Regulates VCAM-1 and Synergizes with IL-4 in Eotaxin Expression: Involvement of STAT6. Journal of Immunology. 176:4352-4360. 2006
- Interleukin‐1 in combination with oncostatin M up‐regulates multiple genes in chondrocytes: Implications for cartilage destruction and repair. Arthritis and Rheumatism. 54:540-550. 2006
- Mainstream Cigarette Smoke Exposure Attenuates Airway Immune Inflammatory Responses to Surrogate and Common Environmental Allergens in Mice, Despite Evidence of Increased Systemic Sensitization. Journal of Immunology. 175:2834-2842. 2005
- A model of inflammatory arthritis highlights a role for oncostatin M in pro-inflammatory cytokine-induced bone destruction via RANK/RANKL.. Arthritis Research & Therapy. 7:R57-R57. 2005
- Matrix catabolism in arthritis: priming the guns with oncostatin M.. Journal of Rheumatology. 31:2326-2328. 2004
- Mitogen-activated protein kinases Erk1/2 and p38 are required for maximal regulation of TIMP-1 by oncostatin M in murine fibroblasts. Cellular Signalling. 16:1123-1132. 2004
- Oncostatin M in combination with tumor necrosis factor α induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo. Arthritis and Rheumatism. 48:3404-3418. 2003
- Adenoviral Gene Transfer of Interleukin-1 in Combination with Oncostatin M Induces Significant Joint Damage in a Murine Model. American Journal of Pathology. 162:1975-1984. 2003
- Growth plate damage, a feature of juvenile idiopathic arthritis, can be induced by adenoviral gene transfer of oncostatin M: A comparative study in gene‐deficient mice. Arthritis and Rheumatism. 48:1750-1761. 2003
- Adenoviral Transfer of the Murine Oncostatin M Gene Suppresses Dextran-Sodium Sulfate-Induced Colitis. Journal of Interferon and Cytokine Research. 23:193-201. 2003
- Oncostatin M Regulates Eotaxin Expression in Fibroblasts and Eosinophilic Inflammation in C57BL/6 Mice. Journal of Immunology. 170:548-555. 2003
- Synergistic interactions of proinflammatory cytokines with oncostatin M: implications for joint destruction. Arthritis Research & Therapy. 5:71-71. 2003
- Editorial. British Journal of Anaesthesia. 89:1-2. 2002
- Adenoviral Transfer of Murine Oncostatin M Elicits Periosteal Bone Apposition in Knee Joints of Mice, Despite Synovial Inflammation and Up-Regulated Expression of Interleukin-6 and Receptor Activator of Nuclear Factor-κB Ligand. American Journal of Pathology. 160:1733-1743. 2002
- Local interleukin‐12 gene transfer promotes conversion of an acute arthritis to a chronic destructive arthritis. Arthritis and Rheumatism. 46:1379-1389. 2002
- Modulation of extracellular matrix using adenovirus vectors. Biochemical Society Transactions. 30:107-111. 2002
- Intra-articular IL-10 gene transfer regulates the expression of collagen-induced arthritis (CIA) in the knee and ipsilateral paw. Clinical and Experimental Immunology. 120:375-383. 2001
- Modulation of extracellular matrix using adenovirus vectors. Biochemical Society Transactions. 30:107-107. 2001
- Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation. Osteoarthritis and Cartilage. 9:128-136. 2001
- Recombinant adenovirus vectors expressing interleukin‐5 and ‐6 specifically enhance mucosal immunoglobulin A responses in the lung. Immunology. 101:388-396. 2000
- Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability. American Journal of Physiology - Gastrointestinal and Liver Physiology. 279:G1094-G1103. 2000
- Murine Oncostatin M Stimulates Mouse Synovial Fibroblasts in Vitro and Induces Inflammation and Destruction in Mouse Joints in Vivo. American Journal of Pathology. 157:1187-1196. 2000
- Interleukins 4 and 13 Increase Intestinal Epithelial Permeability by a Phosphatidylinositol 3-Kinase Pathway. Journal of Biological Chemistry. 275:29132-29137. 2000
- Receptor Subunit-specific Action of Oncostatin M in Hepatic Cells and Its Modulation by Leukemia Inhibitory Factor. Journal of Biological Chemistry. 275:25273-25285. 2000
- Endotoxin-induced Renal Inflammatory Response. Journal of Biological Chemistry. 275:22014-22019. 2000
- IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion. Journal of Clinical Investigation. 105:1697-1710. 2000
- STIMULATION OF OSTEOCLAST DIFFERENTIATION IN VITRO BY MOUSE ONCOSTATIN M, LEUKAEMIA INHIBITORY FACTOR, CARDIOTROPHIN-1 AND INTERLEUKIN 6: SYNERGY WITH DEXAMETHASONE. Cytokine. 12:613-621. 2000
- T Cell-Derived Suppressive Activity: Evidence of Autocrine Noncytolytic Control of HIV Type 1 Transcription and Replication. AIDS Research and Human Retroviruses. 15:1553-1561. 1999
- Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction. Journal of Immunology. 163:4546-4556. 1999
- Adenovirus Vector Expressing Mouse Oncostatin M Induces Acute-Phase Proteins and TIMP-1 ExpressionIn Vivoin Mice. Journal of Interferon and Cytokine Research. 19:1195-1205. 1999
- Oncostatin M Stimulates c-Fos to Bind a Transcriptionally Responsive AP-1 Element within the Tissue Inhibitor of Metalloproteinase-1 Promoter. Journal of Biological Chemistry. 273:5211-5218. 1998
- Bronchial myofibroblasts and tissue remodelling in asthma.. Canadian Respiratory Journal. 5:59-61. 1998
- Oncostatin M stimulates monocyte chemoattractant protein‐1‐ and interleukin‐1‐induced matrix metalloproteinase‐1 production by human synovial fibroblasts in vitro. Arthritis and Rheumatism. 40:2139-2146. 1997
- Regulation of tissue inhibitor of metalloproteinase-1 in fibroblasts and acute phase proteins in hepatocytes in vitro by mouse oncostatin M, cardiotrophin-1, and IL-6.. Journal of Immunology. 159:2431-2437. 1997
- Oncostatin M, but Not Interleukin-6 or Leukemia Inhibitory Factor, Stimulates Expression of Alpha1-Proteinase Inhibitor in A549 Human Alveolar Epithelial Cells. Journal of Interferon and Cytokine Research. 17:337-346. 1997
- Antibodies to rat soluble IL‐6 receptor stimulate B9 hybridoma cell proliferation. FEBS Letters. 408:182-186. 1997
- CD8+ T-cell-mediated suppression of HIV-1 long terminal repeat-driven gene expression is not modulated by the CC chemokines RANTES, macrophage inflammatory protein (MIP)-1α and MIP-1β. AIDS. 11:575-580. 1997
- Reduced Preference for Sucrose in Autoimmune Mice. Brain Research Bulletin. 44:155-165. 1997
- Overexpression of RANTES using a recombinant adenovirus vector induces the tissue-directed recruitment of monocytes to the lung.. Journal of Immunology. 157:5076-5084. 1996
- Prostaglandin E2 enhances interleukin 8 (IL-8) and IL-6 but inhibits GMCSF production by IL-1 stimulated human synovial fibroblasts in vitro.. Journal of Rheumatology. 23:862-868. 1996
- Measurement of Interleukin 6. Current Protocols in Immunology. 17:Unit-6.6. 1996
- Modulation of the Anchorage-Independent Phenotype of Human Lung Fibroblasts Obtained from Fibrotic Tissue Following Culture with Retinoid and Corticosteroid. Experimental Lung Research. 22:231-244. 1996
- Murine Cardiotrophin-1 Stimulates the Acute-Phase Response in Rat Hepatocytes and H35 Hepatoma Cells. Journal of Interferon and Cytokine Research. 16:69-75. 1996
- Oncostatin M inhibits IL-1-induced expression of IL-8 and granulocyte-macrophage colony-stimulating factor by synovial and lung fibroblasts.. Journal of Immunology. 156:343-349. 1996
- Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130). Cytokine. 7:503-509. 1995
- Prostanoid enhancement of interleukin-6 production by rat peritoneal mast cells.. Journal of Immunology. 154:4759-4767. 1995
- The Role of Plasma from Platelet Concentrates in Transfusion Reactions. Survey of Anesthesiology. 39:135-135. 1995
- The Role of the Plasma from Platelet Concentrates in Transfusion Reactions. New England Journal of Medicine. 331:625-628. 1994
- Tissue directed recruitment of mononuclear cells to the lung using a recombinant adenovirus expressing murine RANTES. Cytokine. 6:544-544. 1994
- Anchorage-independent colony growth of pulmonary fibroblasts derived from fibrotic human lung tissue.. Journal of Clinical Investigation. 93:1525-1532. 1994
- Interaction between oncostatin M, interleukin 1 and prostaglandin E2 in induction of IL-6 expression in human fibroblasts. Cytokine. 6:40-47. 1994
- Construction of recombinant human type 5 adenoviruses expressing rodent IL-6 genes. An approach to investigate in vivo cytokine function.. Journal of Immunology. 151:5145-5153. 1993
- The expression of matrix metalloproteinases and their inhibitors by pig synovial cells and their regulation by combinations of cytokines and growth factors. Comparative Biochemistry and Physiology -- Part B: Biochemistry and. 106:691-704. 1993
- Immunomodulatory properties of diazepam-binding inhibitor: Effect on human interleukin-6 secretion, lymphocyte proliferation and natural killer cell activity in vitro. Neuropeptides. 25:207-211. 1993
- Selective regulation of metalloproteinase inhibitor (TIMP-1) by oncostatin M in fibroblasts in culture.. Journal of Immunology. 150:5596-5603. 1993
- Regulation of IL-6 and the hepatic IL-6 receptor in acute inflammation in vivo. Cytokine. 5:1-7. 1993
- Synoviocyte derived granulocyte macrophage colony stimulating factor mediates the survival of human lymphocytes.. Journal of Rheumatology. 19:1065-1069. 1992
- Recombinant oncostatin M stimulates the production of acute phase proteins in HepG2 cells and rat primary hepatocytes in vitro.. Journal of Immunology. 148:1731-1736. 1992
- IL6 and the acute phase reaction. Research in Immunology. 143:755-759. 1992
- Molecular cloning and sequence of porcine interleukin 6 cDNA and expression of mRNA in synovial fibroblasts in vitro. Cytokine. 3:269-276. 1991
- Porcine Collagenase from Synovial Fibroblasts: cDNA Sequence and Modulation of Expression of RNA In Vitro by Various Cytokines. Matrix Biology. 11:161-167. 1991
- Cytokine control of acute phase protein expression.. European Cytokine Network. 2:89-98. 1991
- IFN-BETA-2 BSF2 IL-6 IS THE MONOCYTE-DERIVED HSF THAT REGULATES RECEPTOR-SPECIFIC ACUTE PHASE GENE-REGULATION IN HEPATOCYTES. Annals of the New York Academy of Sciences. 557:46-59. 1989
- IFNβ2/BSF2/IL‐6 Is the Monocyte‐derived HSF That Regulates Receptor‐specific Acute Phase Gene Regulation in Hepatocytesa. Annals of the New York Academy of Sciences. 557:46-59. 1989
- SpontaneousIn VitroRelease of Alveolar-Macrophage Cytokines after the Intratracheal Instillation of Bleomycin in Rats: Characterization and Kinetic Studies. American Journal of Respiratory and Critical Care Medicine. 137:1135-1140. 1988
- Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells.. Journal of Immunology. 139:4122-4128. 1987
- Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.. Proceedings of the National Academy of Sciences of the United States of America. 84:7251-7255. 1987
- Na+/H+ exchange is the major mechanism of pH regulation in cultured sympathetic neurons: Measurements in single cell bodies and neurites using a fluorescent pH indicator. Neuroscience. 22:1093-1102. 1987
- Active suppression of host-versus-graft reaction in pregnant mice. Cellular Immunology. 99:140-149. 1986
- Stereospecific binding sites for [3H]nicotinamide adenine dinucleotide in the rat brain. European Journal of Pharmacology. 116:121-127. 1985
- IgA-mediated phagocytosis by mouse alveolar macrophages.. American Journal of Respiratory and Critical Care Medicine. 132:82-85. 1985
- In vivo initiation of unstimulated in vitro interleukin-1 release by alveolar macrophages.. American Journal of Respiratory and Critical Care Medicine. 131:326-330. 1985
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- Multinucleate giant cells in murine and rat lungs during Nippostrongylus brasiliensis infections. A study of the kinetics of the response in vivo, cytochemistry, IgG‐ and C3‐mediated functions. Parasite Immunology. 7:11-18. 1985
- Changes in free-calcium levels and pH in synaptosomes during transmitter release. Biochimica et Biophysica Acta: international journal of biochemistry and biophysics. 803:215-220. 1984
- The expression of IgA Fc receptors on murine eosinophils. The FASEB Journal. 43. 1984
- Fc receptors for IgA and other immunoglobulins on resident and activated alveolar macrophages. Molecular Immunology. 20:1029-1037. 1983
- Nicotinamide adenine dinucleotide depresses synaptic transmission in the hippocampus and has specific binding sites on the synaptic membranes. British Journal of Pharmacology. 79:553-564. 1983