Journal article
Oncostatin M induces IL-33 expression in liver endothelial cells in mice and expands ST2+CD4+ lymphocytes
Abstract
Interleukin (IL)-33 is crucially involved in liver pathology and drives hepatoprotective functions. However, the regulation of IL-33 by cytokines of the IL-6 family, including oncostatin M (OSM) and IL-6, is not well studied. The aim of the present study was to determine whether OSM mediates regulation of IL-33 expression in liver cells. Intramuscular administration in mice of an adenovirus encoding OSM (AdOSM) leads to increase in expression …
Authors
Arshad MI; Guihard P; Danger Y; Noel G; Le Seyec J; Boutet M-A; Richards CD; L'Helgoualc'h A; Genet V; Lucas-Clerc C
Journal
AJP Gastrointestinal and Liver Physiology, Vol. 309, No. 7, pp. g542–g553
Publisher
American Physiological Society
Publication Date
October 1, 2015
DOI
10.1152/ajpgi.00398.2014
ISSN
0193-1857