Journal article
Interaction among hepatocyte-stimulating factors, interleukin 1, and glucocorticoids for regulation of acute phase plasma proteins in human hepatoma (HepG2) cells.
Abstract
Human hepatoma (HepG2) cells respond to unfractionated conditioned media of human squamous carcinoma (COLO-16) cells and lipopolysaccharide-stimulated human peripheral blood monocytes by increasing the synthesis of alpha 1-acid glycoprotein, haptoglobin, complement C3, alpha 1-antichymotrypsin, alpha 1-antitrypsin, and fibrinogen, while decreasing the synthesis of albumin. The regulation of the acute phase proteins is mediated by …
Authors
Baumann H; Richards C; Gauldie J
Journal
The Journal of Immunology, Vol. 139, No. 12, pp. 4122–4128
Publisher
Oxford University Press (OUP)
Publication Date
December 15, 1987
DOI
10.4049/jimmunol.139.12.4122
ISSN
0022-1767