Journal article
Interleukin‐1 in combination with oncostatin M up‐regulates multiple genes in chondrocytes: Implications for cartilage destruction and repair
Abstract
OBJECTIVE: To identify the genes up-regulated by interleukin-1 (IL-1) in combination with oncostatin M (OSM) in chondrocytes that may be involved in mechanisms of cartilage repair and degradation.
METHODS: Gene microarray and real-time polymerase chain reaction (PCR) experiments were performed using RNA from SW1353 chondrocytes and primary human articular chondrocytes. Sections prepared from murine joints, injected with adenovirus vectors …
Authors
Barksby HE; Hui W; Wappler I; Peters HH; Milner JM; Richards CD; Cawston TE; Rowan AD
Journal
Arthritis & Rheumatism, Vol. 54, No. 2, pp. 540–550
Publisher
Wiley
Publication Date
February 2006
DOI
10.1002/art.21574
ISSN
0004-3591