Multigene Family Concept

subject area of

• Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B‐band lipopolysaccharide gene cluster  Journal Articles
• Burkholderia from Fungus Gardens of Fungus-Growing Ants Produces Antifungals That Inhibit the Specialized Parasite Escovopsis  Journal Articles
• A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor  Journal Articles
• A Common Nomenclature for Members of the Tissue (Glandular) Kallikrein Gene Families  Journal Articles
• A Comprehensive Expression Analysis of the Arabidopsis Proline-rich Extensin-like Receptor Kinase Gene Family using Bioinformatic and Experimental Approaches  Journal Articles
• A Cryptic Polyene Biosynthetic Gene Cluster in Streptomyces calvus Is Expressed upon Complementation with a Functional bldA Gene  Journal Articles
• A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism  Journal Articles
• A mouse atlas of gene expression: Large-scale digital gene-expression profiles from precisely defined developing C57BL/6J mouse tissues and cells  Journal Articles
• A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines  Journal Articles
• Allelic Stability of VNTR Locus 3’αHVR: Linkage Disequilibrium with the Common α-Thalassaemia-1-Deletion of South-East Asia (--SEA/)  Journal Articles
• An ABC-Type Cobalt Transport System Is Essential for Growth of Sinorhizobium melilotiat Trace Metal Concentrations  Journal Articles
• Ancient Antibiotics, Ancient Resistance  Journal Articles
• Assembly and clustering of natural antibiotics guides target identification  Journal Articles
• Automated Identification of Depsipeptide Natural Products by an Informatic Search Algorithm  Journal Articles
• Bioinformatic discovery of a toxin family in Chryseobacterium piperi with sequence similarity to botulinum neurotoxins  Journal Articles
• Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide β-lactone  Journal Articles
• Biosynthesis of the Fluorinated Natural Product Nucleocidin in Streptomyces calvus Is Dependent on the bldA‐Specified Leu‐tRNA^UUA Molecule  Journal Articles
• Biosynthetic Characterization and Chemoenzymatic Assembly of the Cryptophycins. Potent Anticancer Agents from Nostoc Cyanobionts  Journal Articles
• Biosynthetic Pathway for Mannopeptimycins, Lipoglycopeptide Antibiotics Active against Drug-Resistant Gram-Positive Pathogens  Journal Articles
• Botulinum neurotoxin homologs in non‐Clostridium species  Journal Articles
• Characterization of vanY, a DD-carboxypeptidase from vancomycin-resistant Enterococcus faecium BM4147  Journal Articles
• Cloning and analysis of duplicated rfbM and rfbK genes involved in the formation of GDP-mannose in Escherichia coli O9:K30 and participation of rfb genes in the synthesis of the group I K30 capsular polysaccharide  Journal Articles
• Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: Structural similarity to the ubiquitous ‘chaperonin’ family of heat-shock proteins  Journal Articles
• ClpP inhibitors are produced by a widespread family of bacterial gene clusters  Journal Articles
• Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity  Journal Articles
• Common biosynthetic origins for polycyclic tetramate macrolactams from phylogenetically diverse bacteria  Journal Articles
• Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease  Journal Articles
• Comparative analysis of function and interaction of transcription factors in nematodes: Extensive conservation of orthology coupled to rapid sequence evolution  Journal Articles
• Comparative analysis of non-coding RNAs in the antibiotic-producing Streptomyces bacteria  Journal Articles
• Comparative and genetic analysis of the four sequenced Paenibacillus polymyxa genomes reveals a diverse metabolism and conservation of genes relevant to plant-growth promotion and competitiveness  Journal Articles
• Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences  Journal Articles
• Context matters: assessing the impacts of genomic background and ecology on microbial biosynthetic gene cluster evolution.  Journal Articles
• Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders  Journal Articles
• Cytokine‐induced expression of mRNAs for chemotactic factors in human synovial cells and fibroblasts  Journal Articles
• Differential Expression of a Panel of Ten CNTN1-Associated Genes during Prostate Cancer Progression and the Predictive Properties of the Panel towards Prostate Cancer Relapse  Journal Articles
• Diversity and relationships among strains of culturable yeasts in agricultural soils in Cameroon  Journal Articles
• Drosophila neuroglian: A member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1  Journal Articles
• Evolution of genes and genomes on the Drosophila phylogeny  Journal Articles
• Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling  Journal Articles
• Evolutionary and functional diversity of the Pseudomonas type IVa pilin island  Journal Articles
• Expression of the kallikrein gene family in normal and Alzheimer's disease brain  Journal Articles
• Fat Infiltration in Muscle: New Evidence for Familial Clustering and Associations With Diabetes  Journal Articles
• Fetal hemoglobin in sickle cell anemia: a glass half full?  Journal Articles
• Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster  Journal Articles
• Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis.  Journal Articles
• Functional analysis of genes responsible for the synthesis of the B-band O antigen of Pseudomonas aeruginosa serotype O6 lipopolysaccharide The GenBank accession number for the sequence reported in this paper is AF035937.  Journal Articles
• Functional metagenomics reveals abundant polysaccharide-degrading gene clusters and cellobiose utilization pathways within gut microbiota of a wood-feeding higher termite  Journal Articles
• Generation and Analysis of a Mouse Intestinal Metatranscriptome through Illumina Based RNA-Sequencing  Journal Articles
• Generation of a new adenovirus type 12-inducible fragile site by insertion of an artificial U2 locus in the human genome.  Journal Articles
• Genetic Variants and Susceptibility to Neurological Complications Following West Nile Virus Infection  Journal Articles
• Genomic and transcriptomic analyses of the tangerine pathotype of Alternaria alternata in response to oxidative stress  Journal Articles
• Genomic insights into the evolution and ecology of botulinum neurotoxins  Journal Articles
• Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms  Journal Articles
• Hb Castilla [β32(B14)Leu → Arg] Caused by a De Novo Mutation  Journal Articles
• Hb S/ +-thalassemia due to Hb sickle and a novel deletion of DNase I hypersensitive sites HS3 and HS4 of the   locus control region  Journal Articles
• HbVar database of human hemoglobin variants and thalassemia mutations: 2007 update  Journal Articles
• Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus  Journal Articles
• Hemoglobin Bart's Disease in an Italian Boy  Journal Articles
• Heterologous expression-facilitated natural products’ discovery in actinomycetes  Journal Articles
• Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics  Journal Articles
• How To Make a Glycopeptide: A Synthetic Biology Approach To Expand Antibiotic Chemical Diversity  Journal Articles
• Human ERMAP: An Erythroid Adhesion/Receptor Transmembrane Protein  Journal Articles
• Human embryonic zeta-globin chain expression in deletional alpha- thalassemias  Journal Articles
• Identification and characterization of the siderochelin biosynthetic gene cluster via coculture.  Journal Articles
• Identification and functional analyses of sex determination genes in the sexually dimorphic stag beetle Cyclommatus metallifer  Journal Articles
• Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium  Journal Articles
• Identification of a Hydroxyproline Transport System in the Legume Endosymbiont Sinorhizobium meliloti  Journal Articles
• Identification of a diphtheria toxin‐like gene family beyond the Corynebacterium genus  Journal Articles
• Identification of likely orthologs of tobacco salicylic acid‐binding protein 2 and their role in systemic acquired resistance in Arabidopsis thaliana  Journal Articles
• Inducing Global Expression of Actinobacterial Biosynthetic Gene Clusters  Journal Articles
• Insights into the evolutionary origins of clostridial neurotoxins from analysis of the Clostridium botulinum strain A neurotoxin gene cluster  Journal Articles
• Interplay between Nucleoid-Associated Proteins and Transcription Factors in Controlling Specialized Metabolism in Streptomyces  Journal Articles
• Investigating Immune Gene Signatures in Peripheral Blood from Subjects with Allergic Rhinitis Undergoing Nasal Allergen Challenge  Journal Articles
• Kinetic mechanism of the GCN5-related chromosomal aminoglycoside acetyltransferase AAC(6')-Ii from Enterococcus faecium: evidence of dimer subunit cooperativity  Journal Articles
• Linear Peptides Are the Major Products of a Biosynthetic Pathway That Encodes for Cyclic Depsipeptides  Journal Articles
• Linkage analysis for three coagulation factors clustering on chromosome 13q34: factor VII, factor X and protein Z  Journal Articles
• Lipopolysaccharide core phosphates are required for viability and intrinsic drug resistance in Pseudomonas aeruginosa  Journal Articles
• Madurastatin D1 and D2, Oxazoline Containing Siderophores Isolated from an Actinomadura sp.  Journal Articles
• Metabolic and co-expression network-based analyses associated with nitrate response in rice  Journal Articles
• Minimal ProtoHox cluster inferred from bilaterian and cnidarian Hox complements  Journal Articles
• Minimum Information about a Biosynthetic Gene cluster  Journal Articles
• Multicopy gene family evolution on primate Y chromosomes  Journal Articles
• Multiple Imprinted and Stemness Genes Provide a Link between Normal and Tumor Progenitor Cells of the Developing Human Kidney  Journal Articles
• Multiple conformations facilitate PilT function in the type IV pilus  Journal Articles
• Noncanonical Vancomycin Resistance Cluster from Desulfitobacterium hafniense Y51  Journal Articles
• Novel Molecular Signatures in the PIP4K/PIP5K Family of Proteins Specific for Different Isozymes and Subfamilies Provide Important Insights into the Evolutionary Divergence of this Protein Family  Journal Articles
• Novel Repressor of Escherichia coli O157:H7 Motility Encoded in the Putative Fimbrial Cluster OI-1  Journal Articles
• Nuclear import of the BTB/POZ transcriptional regulator Kaiso  Journal Articles
• Nucleotide Sequences and Novel Structural Features of Human and Chinese Hamster hsp60 (Chaperonin) Gene Families  Journal Articles
• Optimizing dimodular nonribosomal peptide synthetases and natural dipeptides in an Escherichia coli heterologous host  Journal Articles
• Origin and evolution of gene families in Bacteria and Archaea  Journal Articles
• Pel Polysaccharide Biosynthesis Requires an Inner Membrane Complex Comprised of PelD, PelE, PelF, and PelG  Journal Articles
• Perspective: Synthetic biology revives antibiotics  Journal Articles
• Phylogenetic Analysis of the Cytochrome P450 3 (CYP3) Gene Family  Journal Articles
• Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species.  Journal Articles
• Phylogenetic and Functional Analysis of the Vertebrate Cytochrome P450 2 Family  Journal Articles
• Phylogenetic reconciliation reveals the natural history of glycopeptide antibiotic biosynthesis and resistance  Journal Articles
• Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching  Journal Articles
• Protein-leucine ingestion activates a regenerative inflammo-myogenic transcriptome in skeletal muscle following intense endurance exercise  Journal Articles
• Proximodistal subdivision ofDrosophilalegs and wings: theelbow-no ocelligene complex  Journal Articles
• Pseudomonas aeruginosa B-band O-antigen chain length is modulated by Wzz (Ro1)  Journal Articles
• Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production  Journal Articles
• Redundant and non-functional guide RNA genes in Trypanosoma brucei are a consequence of multiple genes per minicircle  Journal Articles
• Regulation and Properties of PstSCAB, a High-Affinity, High-Velocity Phosphate Transport System ofSinorhizobium meliloti  Journal Articles
• Regulation of a Novel Gene Cluster Involved in Secondary Metabolite Production in Streptomyces coelicolor  Journal Articles
• SANDPUMA: ensemble predictions of nonribosomal peptide chemistry reveal biosynthetic diversity across Actinobacteria  Journal Articles
• Seeing green bacteria in a new light: genomics-enabled studies of the photosynthetic apparatus in green sulfur bacteria and filamentous anoxygenic phototrophic bacteria  Journal Articles
• Self Resistance to the Atypical Cationic Antimicrobial Peptide Edeine of Brevibacillus brevis Vm4 by the N-Acetyltransferase EdeQ  Journal Articles
• Selvamicin, an atypical antifungal polyene from two alternative genomic contexts  Journal Articles
• Severe fetal and neonatal hemolytic anemia due to a 198 kb deletion removing the complete β‐globin gene cluster  Journal Articles
• Sickle cell disease caused by heterozygosity for Hb S and novel LCR deletion: Report of two patients  Journal Articles
• Single-Tube Multiplex-PCR Screen for Anti-3.7 and Anti-4.2 α-Globin Gene Triplications  Journal Articles
• Structural and Functional Heterogeneity in the CD200R Family of Immunoregulatory Molecules and their Expression at the Feto‐maternal Interface  Journal Articles
• Structures and biosynthesis of 12-membered macrocyclic depsipeptides from Streptomyces sp. ML55  Journal Articles
• Substitution rate variation in closely related rodent species  Journal Articles
• Testing the Infinitely Many Genes Model for the Evolution of the Bacterial Core Genome and Pangenome  Journal Articles
• The ADEP Biosynthetic Gene Cluster in Streptomyces hawaiiensis NRRL 15010 Reveals an Accessory clpP Gene as a Novel Antibiotic Resistance Factor  Journal Articles
• The Effects of Weak Genetic Perturbations on the Transcriptome of the Wing Imaginal Disc and Its Association With Wing Shape in Drosophila melanogaster  Journal Articles
• The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum‐sensing signal molecule  Journal Articles
• The Mla Pathway Plays an Essential Role in the Intrinsic Resistance of Burkholderia cepacia Complex Species to Antimicrobials and Host Innate Components  Journal Articles
• The YebC Family Protein PA0964 Negatively Regulates thePseudomonas aeruginosaQuinolone Signal System and Pyocyanin Production  Journal Articles
• The alpha-globin gene cluster: genetics and disorders.  Journal Articles
• The cytochrome P450 (CYP) superfamily in cnidarians  Journal Articles
• The evolution of the class A scavenger receptors  Journal Articles
• The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non-ribosomal peptide synthetase gene The GenBank accession number for the sequence reported in this paper is AF262220.  Journal Articles
• The pdx genetic marker adjacent to the chloramphenicol biosynthesis gene cluster in Streptomyces venezuelae ISP5230: functional characterization The GenBank accession number for the sequence reported in this paper is AF286159.  Journal Articles
• The porcine skin microbiome exhibits broad fungal antagonism  Journal Articles
• The rcsA gene of Escherichia coli O9:K30:H12 is involved in the expression of the serotype-specific group I K (capsular) antigen  Journal Articles
• Three rhamnosyltransferases responsible for assembly of the A‐band D‐rhamnan polysaccharide in Pseudomonas aeruginosa: a fourth transferase, WbpL, is required for the initiation of both A‐band and B‐band lipopolysaccharide synthesis  Journal Articles
• Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells  Journal Articles
• Trichlorination of a Teicoplanin-Type Glycopeptide Antibiotic by the Halogenase StaI Evades Resistance  Journal Articles
• Type VI Secretion System-Associated Gene Clusters Contribute to Pathogenesis of Salmonella enterica Serovar Typhimurium  Journal Articles
• Unlocking the trove of metabolic treasures: activating silent biosynthetic gene clusters in bacteria and fungi  Journal Articles
• Variants of ZBTB7A (LRF) and its β-globin gene cluster binding motifs in sickle cell anemia  Journal Articles
• zol and fai: large-scale targeted detection and evolutionary investigation of gene clusters.  Journal Articles