Multigene Family Concept

subject area of

• Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene cluster  Academic Article
• A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor  Academic Article
• A Common Nomenclature for Members of the Tissue (Glandular) Kallikrein Gene Families  Academic Article
• A Comprehensive Expression Analysis of the Arabidopsis Proline-rich Extensin-like Receptor Kinase Gene Family using Bioinformatic and Experimental Approaches  Academic Article
• A Cryptic Polyene Biosynthetic Gene Cluster in Streptomyces calvus Is Expressed upon Complementation with a Functional bldA Gene  Academic Article
• A Type VI Secretion-Related Pathway in Bacteroidetes Mediates Interbacterial Antagonism  Academic Article
• A transglutaminase homologue as a condensation catalyst in antibiotic assembly lines  Academic Article
• Allelic Stability of VNTR Locus 3’αHVR: Linkage Disequilibrium with the Common α-Thalassaemia-1-Deletion of South-East Asia (--SEA/)  Academic Article
• An ABC-Type Cobalt Transport System Is Essential for Growth of Sinorhizobium melilotiat Trace Metal Concentrations  Academic Article
• Ancient Antibiotics, Ancient Resistance  Academic Article
• Assembly and clustering of natural antibiotics guides target identification  Academic Article
• Automated Identification of Depsipeptide Natural Products by an Informatic Search Algorithm  Academic Article
• Bioinformatic discovery of a toxin family in Chryseobacterium piperi with sequence similarity to botulinum neurotoxins  Academic Article
• Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide β-lactone  Academic Article
• Biosynthesis of the Fluorinated Natural Product Nucleocidin inStreptomyces calvusIs Dependent on thebldA-Specified Leu-tRNA^UUAMolecule  Academic Article
• Biosynthetic Characterization and Chemoenzymatic Assembly of the Cryptophycins. Potent Anticancer Agents from Nostoc Cyanobionts  Academic Article
• Biosynthetic Pathway for Mannopeptimycins, Lipoglycopeptide Antibiotics Active against Drug-Resistant Gram-Positive Pathogens  Academic Article
• Botulinum neurotoxin homologs in non-Clostridium species  Academic Article
• Characterization of vanY, a DD-carboxypeptidase from vancomycin-resistant Enterococcus faecium BM4147  Academic Article
• Cloning and analysis of duplicated rfbM and rfbK genes involved in the formation of GDP-mannose in Escherichia coli O9:K30 and participation of rfb genes in the synthesis of the group I K30 capsular polysaccharide  Academic Article
• Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: Structural similarity to the ubiquitous ‘chaperonin’ family of heat-shock proteins  Academic Article
• ClpP inhibitors are produced by a widespread family of bacterial gene clusters  Academic Article
• Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity  Academic Article
• Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease  Academic Article
• Comparative analysis of function and interaction of transcription factors in nematodes: Extensive conservation of orthology coupled to rapid sequence evolution  Academic Article
• Comparative analysis of non-coding RNAs in the antibiotic-producing Streptomyces bacteria  Academic Article
• Comparative and genetic analysis of the four sequenced Paenibacillus polymyxa genomes reveals a diverse metabolism and conservation of genes relevant to plant-growth promotion and competitiveness  Academic Article
• Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences  Academic Article
• Convergence of Genes and Cellular Pathways Dysregulated in Autism Spectrum Disorders  Academic Article
• Cytokine-induced expression of mRNAs for chemotactic factors in human synovial cells and fibroblasts  Academic Article
• Differential Expression of a Panel of Ten CNTN1-Associated Genes during Prostate Cancer Progression and the Predictive Properties of the Panel towards Prostate Cancer Relapse  Academic Article
• Diversity and relationships among strains of culturable yeasts in agricultural soils in Cameroon  Academic Article
• Drosophila neuroglian: A member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule L1  Academic Article
• Evolution of genes and genomes on the Drosophila phylogeny  Academic Article
• Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling  Academic Article
• Evolutionary and functional diversity of thePseudomonastype IVa pilin island  Academic Article
• Expression of the kallikrein gene family in normal and Alzheimer's disease brain  Academic Article
• Fat Infiltration in Muscle: New Evidence for Familial Clustering and Associations With Diabetes  Academic Article
• Fetal hemoglobin in sickle cell anemia: a glass half full?  Academic Article
• Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5′ olfactory receptor gene cluster  Academic Article
• Function of PEA3 Ets transcription factors in mammary gland development and oncogenesis.  Academic Article
• Functional analysis of genes responsible for the synthesis of the B-band O antigen of Pseudomonas aeruginosa serotype O6 lipopolysaccharide The GenBank accession number for the sequence reported in this paper is AF035937.  Academic Article
• Generation and Analysis of a Mouse Intestinal Metatranscriptome through Illumina Based RNA-Sequencing  Academic Article
• Generation of a new adenovirus type 12-inducible fragile site by insertion of an artificial U2 locus in the human genome.  Academic Article
• Genetic Variants and Susceptibility to Neurological Complications Following West Nile Virus Infection  Academic Article
• Genomic and transcriptomic analyses of the tangerine pathotype of Alternaria alternata in response to oxidative stress  Academic Article
• Genomic insights into the evolution and ecology of botulinum neurotoxins  Academic Article
• Glycopeptide antibiotic resistance genes in glycopeptide-producing organisms  Academic Article
• Hb Castilla [β32(B14)Leu → Arg] Caused by a De Novo Mutation  Academic Article
• Hb S/ +-thalassemia due to Hb sickle and a novel deletion of DNase I hypersensitive sites HS3 and HS4 of the   locus control region  Academic Article
• HbVar database of human hemoglobin variants and thalassemia mutations: 2007 update  Academic Article
• Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus  Academic Article
• Hemoglobin Bart's Disease in an Italian Boy  Academic Article
• Heterologous expression-facilitated natural products’ discovery in actinomycetes  Academic Article
• Hidden antibiotics in actinomycetes can be identified by inactivation of gene clusters for common antibiotics  Academic Article
• How To Make a Glycopeptide: A Synthetic Biology Approach To Expand Antibiotic Chemical Diversity  Academic Article
• Human ERMAP: An Erythroid Adhesion/Receptor Transmembrane Protein  Academic Article
• Human embryonic zeta-globin chain expression in deletional alpha- thalassemias  Academic Article
• Identification and functional analyses of sex determination genes in the sexually dimorphic stag beetle Cyclommatus metallifer  Academic Article
• Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium  Academic Article
• Identification of a Hydroxyproline Transport System in the Legume Endosymbiont Sinorhizobium meliloti  Academic Article
• Identification of a diphtheria toxin‐like gene family beyond theCorynebacteriumgenus  Academic Article
• Identification of likely orthologs of tobacco salicylic acid-binding protein 2 and their role in systemic acquired resistance inArabidopsis thaliana  Academic Article
• Inducing Global Expression of Actinobacterial Biosynthetic Gene Clusters  Academic Article
• Induction of cyclooxygenase-2 in rat vascular smooth muscle cells in vitro and in vivo.  Academic Article
• Insights into the evolutionary origins of clostridial neurotoxins from analysis of the Clostridium botulinum strain A neurotoxin gene cluster  Academic Article
• Interplay between Nucleoid-Associated Proteins and Transcription Factors in Controlling Specialized Metabolism in Streptomyces  Academic Article
• Intracellular targeting, interaction with Src homology 3 (SH3) domains and rolipram-detected conformational switches in cAMP-specific PDE4A phosphodiesterase  Academic Article
• Investigating Immune Gene Signatures in Peripheral Blood from Subjects with Allergic Rhinitis Undergoing Nasal Allergen Challenge  Academic Article
• Kinetic mechanism of the GCN5-related chromosomal aminoglycoside acetyltransferase AAC(6')-Ii from Enterococcus faecium: evidence of dimer subunit cooperativity  Academic Article
• Linkage analysis for three coagulation factors clustering on chromosome 13q34: factor VII, factor X and protein Z  Academic Article
• Lipopolysaccharide core phosphates are required for viability and intrinsic drug resistance in Pseudomonas aeruginosa  Academic Article
• Metabolic and co-expression network-based analyses associated with nitrate response in rice  Academic Article
• Minimal ProtoHox cluster inferred from bilaterian and cnidarian Hox complements  Academic Article
• Minimum Information about a Biosynthetic Gene cluster  Academic Article
• Multicopy gene family evolution on primate Y chromosomes  Academic Article
• Multiple Imprinted and Stemness Genes Provide a Link between Normal and Tumor Progenitor Cells of the Developing Human Kidney  Academic Article
• Multiple conformations facilitate PilT function in the type IV pilus  Academic Article
• Noncanonical Vancomycin Resistance Cluster from Desulfitobacterium hafniense Y51  Academic Article
• Novel Molecular Signatures in the PIP4K/PIP5K Family of Proteins Specific for Different Isozymes and Subfamilies Provide Important Insights into the Evolutionary Divergence of this Protein Family  Academic Article
• Novel Repressor of Escherichia coli O157:H7 Motility Encoded in the Putative Fimbrial Cluster OI-1  Academic Article
• Nuclear import of the BTB/POZ transcriptional regulator Kaiso  Academic Article
• Nucleotide Sequences and Novel Structural Features of Human and Chinese Hamster hsp60 (Chaperonin) Gene Families  Academic Article
• Optimizing dimodular nonribosomal peptide synthetases and natural dipeptides in an Escherichia coli heterologous host  Academic Article
• Origin and evolution of gene families in Bacteria and Archaea  Academic Article
• Pel Polysaccharide Biosynthesis Requires an Inner Membrane Complex Comprised of PelD, PelE, PelF, and PelG  Academic Article
• Perspective: Synthetic biology revives antibiotics  Academic Article
• Phylogenetic Analysis of the Cytochrome P450 3 (CYP3) Gene Family  Academic Article
• Phylogenetic analysis of the 90 kD heat shock family of protein sequences and an examination of the relationship among animals, plants, and fungi species.  Academic Article
• Phylogenetic and Functional Analysis of the Vertebrate Cytochrome P450 2 Family  Academic Article
• Phylogenetic reconciliation reveals the natural history of glycopeptide antibiotic biosynthesis and resistance  Academic Article
• Polyketide and nonribosomal peptide retro-biosynthesis and global gene cluster matching  Academic Article
• Protein-leucine ingestion activates a regenerative inflammo-myogenic transcriptome in skeletal muscle following intense endurance exercise  Academic Article
• Proximodistal subdivision ofDrosophilalegs and wings: theelbow-no ocelligene complex  Academic Article
• Pseudomonas aeruginosa B-band O-antigen chain length is modulated by Wzz (Ro1)  Academic Article
• Quorum sensing in Escherichia coli , Salmonella typhimurium , and Vibrio harveyi : A new family of genes responsible for autoinducer production  Academic Article
• Redundant and non-functional guide RNA genes in Trypanosoma brucei are a consequence of multiple genes per minicircle  Academic Article
• Regulation and Properties of PstSCAB, a High-Affinity, High-Velocity Phosphate Transport System of Sinorhizobium meliloti  Academic Article
• Regulation of a Novel Gene Cluster Involved in Secondary Metabolite Production in Streptomyces coelicolor  Academic Article
• Self Resistance to the Atypical Cationic Antimicrobial Peptide Edeine of Brevibacillus brevis Vm4 by the N-Acetyltransferase EdeQ  Academic Article
• Severe fetal and neonatal hemolytic anemia due to a 198 kb deletion removing the complete β-globin gene cluster  Academic Article
• Sickle cell disease caused by heterozygosity for Hb S and novel LCR deletion: Report of two patients  Academic Article
• Single-Tube Multiplex-PCR Screen for Anti-3.7 and Anti-4.2 α-Globin Gene Triplications  Academic Article
• Structural and Functional Heterogeneity in the CD200R Family of Immunoregulatory Molecules and their Expression at the Feto-maternal Interface  Academic Article
• Structures and biosynthesis of 12-membered macrocyclic depsipeptides from Streptomyces sp. ML55  Academic Article
• Substitution rate variation in closely related rodent species  Academic Article
• Testing the Infinitely Many Genes Model for the Evolution of the Bacterial Core Genome and Pangenome  Academic Article
• The ADEP Biosynthetic Gene Cluster in Streptomyces hawaiiensis NRRL 15010 Reveals an Accessory clpP Gene as a Novel Antibiotic Resistance Factor  Academic Article
• The Effects of Weak Genetic Perturbations on the Transcriptome of the Wing Imaginal Disc and Its Association With Wing Shape in Drosophila melanogaster  Academic Article
• The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule  Academic Article
• The Mla Pathway Plays an Essential Role in the Intrinsic Resistance of Burkholderia cepacia Complex Species to Antimicrobials and Host Innate Components  Academic Article
• The YebC Family Protein PA0964 Negatively Regulates the Pseudomonas aeruginosa Quinolone Signal System and Pyocyanin Production  Academic Article
• The alpha-globin gene cluster: genetics and disorders.  Academic Article
• The cytochrome P450 (CYP) superfamily in cnidarians  Academic Article
• The evolution of the class A scavenger receptors  Academic Article
• The gene cluster for chloramphenicol biosynthesis in Streptomyces venezuelae ISP5230 includes novel shikimate pathway homologues and a monomodular non-ribosomal peptide synthetase gene The GenBank accession number for the sequence reported in this paper is AF262220.  Academic Article
• The genes for small nucleolar RNAs in Trypanosoma brucei are organized in clusters and are transcribed as a polycistronic RNA  Academic Article
• The pdx genetic marker adjacent to the chloramphenicol biosynthesis gene cluster in Streptomyces venezuelae ISP5230: functional characterization The GenBank accession number for the sequence reported in this paper is AF286159.  Academic Article
• The rcsA gene of Escherichia coli O9:K30:H12 is involved in the expression of the serotype-specific group I K (capsular) antigen  Academic Article
• Three rhamnosyltransferases responsible for assembly of the A-band D-rhamnan polysaccharide in Pseudomonas aeruginosa: a fourth transferase, WbpL, is required for the initiation of both A-band and B-band lipopolysaccharide synthesis  Academic Article
• Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells  Academic Article
• Trichlorination of a Teicoplanin-Type Glycopeptide Antibiotic by the Halogenase StaI Evades Resistance  Academic Article
• Type VI Secretion System-Associated Gene Clusters Contribute to Pathogenesis of Salmonella enterica Serovar Typhimurium  Academic Article
• Unlocking the trove of metabolic treasures: activating silent biosynthetic gene clusters in bacteria and fungi  Academic Article
• Variants of ZBTB7A (LRF) and its β-globin gene cluster binding motifs in sickle cell anemia  Academic Article
• p53 compound heterozygosity in a severely affected child with Li-Fraumeni Syndrome  Academic Article