Journal article
Expression of the kallikrein gene family in normal and Alzheimer's disease brain
Abstract
The human kallikrein gene family consists of 15 serine proteases. We examined the expression of the kallikrein genes in human cerebral cortex and hippocampus by RT-PCR and compared their expression between Alzheimer's disease (AD) and control tissue. KLK1, 4, 5, 6, 7, 8, 10, 11, 13 and 14 are expressed in both cerebral cortex and hippocampus. KLK9 is expressed in cortex but not hippocampus, whereas KLK2, 3, 12 and 15 are not expressed in either …
Authors
Shimizu-Okabe C; Yousef GM; Diamandis EP; Yoshida S; Shiosaka S; Fahnestock M
Journal
Neuroreport, Vol. 12, No. 12, pp. 2747–2751
Publisher
Wolters Kluwer
Publication Date
August 2001
DOI
10.1097/00001756-200108280-00031
ISSN
0959-4965