Interplay between Nucleoid-Associated Proteins and Transcription Factors in Controlling Specialized Metabolism in Streptomyces Journal Articles

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abstract

Specialized metabolic clusters in Streptomyces are the source of many clinically prescribed antibiotics. However, many clusters are not expressed in the laboratory due to repression by the nucleoid-associated protein Lsr2.

authors

Zhang, Xiafei
Andres, Sara
Elliot, Marie

status

published

publication date

August 31, 2021

has subject area

0605 Microbiology (FoR)
Bacterial Proteins (MeSH)
Biosynthetic Pathways (MeSH)
Chloramphenicol (MeSH)
Gene Expression Regulation, Bacterial (MeSH)
Multigene Family (MeSH)
Streptomyces (MeSH)
Transcription Factors (MeSH)

published in

mBio Journal