Leukemia, Myeloid, Acute Concept

subject area of

• In Vivo Screening Unveils Pervasive RNA-Binding Protein Dependencies in Leukemic Stem Cells and Identifies ELAVL1 as a Therapeutic Target  Academic Article
• A Review of Pneumatosis Intestinalis in the Setting of Systemic Cancer Treatments, Including Tyrosine Kinase Inhibitors  Academic Article
• A phase 1 trial evaluating thioridazine in combination with cytarabine in patients with acute myeloid leukemia  Academic Article
• A phase I study of tipifarnib combined with conventional induction and consolidation therapy for previously untreated patients with acute myeloid leukemia aged 60 years and over  Academic Article
• A phase I trial of two sequence-specific schedules of decitabine and vorinostat in patients with acute myeloid leukemia  Academic Article
• A phase I/II study of sorafenib in combination with low dose cytarabine in elderly patients with acute myeloid leukemia or high-risk myelodysplastic syndrome from the National Cancer Institute of Canada Clinical Trials Group: trial IND.186  Academic Article
• A pilot study of carboplatin augmentation therapy for patients with poor risk acute non-lymphocytic leukemia  Academic Article
• A randomized controlled trial comparing standard- and low-dose strategies for transfusion of platelets (SToP) to patients with thrombocytopenia  Academic Article
• AML refractory to primary induction with Ida-FLAG has a poor clinical outcome  Academic Article
• ATIR101 administered after T-cell-depleted haploidentical HSCT reduces NRM and improves overall survival in acute leukemia  Academic Article
• Abnormal dopamine receptor signaling allows selective therapeutic targeting of neoplastic progenitors in AML patients  Academic Article
• Acute myelogenous leukemia in adolescents and young adults  Academic Article
• Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche  Academic Article
• Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity  Academic Article
• Adenovirus Infection in Children With Acute Myeloid Leukemia  Academic Article
• American Society of Hematology 2020 guidelines for treating newly diagnosed acute myeloid leukemia in older adults  Academic Article
• An Increase in Cellular Size Variance Contributes to the Increase in Ultrasound Backscatter During Cell Death  Academic Article
• Analysis of the recent cluster of invasive fungal sinusitis at the Toronto Hospital for Sick Children.  Academic Article
• Anthracyclines during induction therapy in acute myeloid leukaemia: a systematic review and meta-analysis  Academic Article
• Assessment of the downstream portion of the mitochondrial pathway of caspase activation in patients with acute myeloid leukemia  Academic Article
• Association Between Corticosteroids and Infection, Sepsis, and Infectious Death in Pediatric Acute Myeloid Leukemia (AML): Results From the Canadian Infections in AML Research Group  Academic Article
• Azacitidine and Venetoclax in Previously Untreated Acute Myeloid Leukemia  Academic Article
• Azacitidine and its role in the upfront treatment of acute myeloid leukemia  Academic Article
• Biological characteristics of newly diagnosed poor prognosis acute myelogenous leukemia  Academic Article
• Biological significance of cell cycle kinetics in 128 standard risk newly diagnosed patients with acute myelocytic leukaemia  Academic Article
• Brief Report: Human Acute Myeloid Leukemia Reprogramming to Pluripotency Is a Rare Event and Selects for Patient Hematopoietic Cells Devoid of Leukemic Mutations  Academic Article
• Canadian multicenter pilot trial of haploidentical donor transplantation  Academic Article
• Cell cycle and clinical characteristics of patients with acute myeloid leukemia and myelodysplasia whose biopsies are reactive with anti-factor VIII antibody  Academic Article
• Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex  Academic Article
• Cellular Reprogramming Allows Generation of Autologous Hematopoietic Progenitors From AML Patients That Are Devoid of Patient-Specific Genomic Aberrations  Academic Article
• Cellular and molecular architecture of hematopoietic stem cells and progenitors in genetic models of bone marrow failure  Academic Article
• Challenges in Cell Fate Acquisition to Scid-Repopulating Activity from Hemogenic Endothelium of hiPSCs Derived from AML Patients Using Forced Transcription Factor Expression  Academic Article
• Changes in the characteristics of the bone marrow during therapy for acute non-lymphocytic leukemia: Relationship to response to remission induction therapy  Academic Article
• Classifying acute leukemia by immunophenotyping: a combined FAB- immunologic classification of AML  Academic Article
• Clinical and biological implications of driver mutations in myelodysplastic syndromes  Academic Article
• Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial  Academic Article
• Clinical manifestations associated with the aberrant expression of the soluble granulocyte-macrophage colony-stimulating factor receptor in patients presenting with haematological malignancies  Academic Article
• Clostridium difficile Infection in Pediatric Acute Myeloid Leukemia  Academic Article
• Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells  Academic Article
• Consolidation Therapy With Autologous Bone Marrow Transplantation in Adults With Acute Myeloid Leukemia: A Meta-analysis  Academic Article
• Diminished AHR Signaling Drives Human Acute Myeloid Leukemia Stem Cell Maintenance  Academic Article
• Direct relationship between remission duration in acute myeloid leukemia and cell cycle kinetics: a leukemia intergroup study  Academic Article
• Duration of first remission and hematopoietic cell transplantation-specific comorbidity index but not age predict survival of patients with AML transplanted in CR2: a retrospective multicenter study  Academic Article
• Economic evaluation of allogeneic bone marrow transplantation: a rudimentary model to generate estimates for the timely formulation of clinical policy.  Academic Article
• Epigenetic maintenance strategies after allogeneic stem cell transplantation in acute myeloid leukemia  Academic Article
• Estrogen Receptor β Is a Novel Target in Acute Myeloid Leukemia  Academic Article
• Evidence-based support for phenotypic drug discovery in acute myeloid leukemia  Academic Article
• Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus  Academic Article
• Factors and inhibitors of blood coagulation and fibrinolysis in acute nonlymphoblastic leukaemia  Academic Article
• Factors associated with the psychological well-being of adults with acute leukemia in remission  Academic Article
• Functional role of BAALC in leukemogenesis  Academic Article
• GFI1 is required for RUNX1/ETO positive acute myeloid leukemia  Academic Article
• GSK3 Deficiencies in Hematopoietic Stem Cells Initiate Pre-neoplastic State that Is Predictive of Clinical Outcomes of Human Acute Leukemia  Academic Article
• Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia  Academic Article
• Hematopoietic colony-stimulating factor priming does not influence survival in acute myeloid leukemia: a meta-analysis of randomized trials  Academic Article
• Hemoglobin abnormalities in neoplastic hematological disorders.  Academic Article
• High-dose cytosine arabinoside: Clinical response to therapy in acute leukemia  Academic Article
• Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia  Academic Article
• Human acute myeloid leukemia stem cells  Academic Article
• Humanized zebrafish enhance human hematopoietic stem cell survival and promote acute myeloid leukemia clonal diversity  Academic Article
• Humanized zebrafish enhance human hematopoietic stem cell survival and promote acute myeloid leukemia clonal diversity.  Academic Article
• Hypoxia factors suffocate leukemic stem cell initiation  Academic Article
• Identification of Chemotherapy-Induced Leukemic-Regenerating Cells Reveals a Transient Vulnerability of Human AML Recurrence  Academic Article
• Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells  Academic Article
• Identification of T-lymphocytic leukemia–initiating stem cells residing in a small subset of patients with acute myeloid leukemic disease  Academic Article
• Impact of intensity of conditioning therapy in patients aged 40–60 years with AML/myelodysplastic syndrome undergoing allogeneic transplantation  Academic Article
• Impact of registration on clinical trials on infection risk in pediatric acute myeloid leukemia  Academic Article
• Importance of Nutrition in the Treatment of Leukemia in Children and Adolescents  Academic Article
• Incidence and predictors of treatment-related mortality in paediatric acute leukaemia in El Salvador  Academic Article
• Infections in pediatric acute promyelocytic leukemia: from the canadian infections in acute myeloid leukemia research group  Academic Article
• Infectious Events Prior to Chemotherapy Initiation in Children with Acute Myeloid Leukemia  Academic Article
• Inferior outcomes for overweight children undergoing allogeneic stem cell transplantation  Academic Article
• Influence of the poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide on macrophage and granulocyte differentiation of HL-60 cells  Academic Article
• Intensive versus less-intensive antileukemic therapy in older adults with acute myeloid leukemia: A systematic review  Academic Article
• Interleukin-1 beta expression and treatment outcome in acute myelogenous leukemia [letter]  Academic Article
• Invasive Rothia infections in children with acute myeloid leukemia: A report from the Canadian infections in AML research group  Academic Article
• Invasive fungal infections in paediatric acute myeloid leukaemia  Academic Article
• LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML  Academic Article
• Less intensive antileukemic therapies (monotherapy and/or combination) for older adults with acute myeloid leukemia who are not candidates for intensive antileukemic therapy: A systematic review and meta-analysis  Academic Article
• Leukapheresis and low-dose chemotherapy do not reduce early mortality in acute myeloid leukemia hyperleukocytosis: A systematic review and meta-analysis  Academic Article
• Leukemia targeting ligands isolated from phage display peptide libraries  Academic Article
• Leukemic progenitor compartment serves as a prognostic measure of cancer stemness in patients with acute myeloid leukemia  Academic Article
• Long Term Outcome of Patients with Acute Myelogenous Leukemia: The Role of Maintenance Therapy, Consolidation Therapy and the Predictive Value of Twoin vitroAssays  Academic Article
• Long-term outcomes to fludarabine and rituximab in Waldenström macroglobulinemia  Academic Article
• Loss of DEP-1 (Ptprj) promotes myeloproliferative disease in FLT3-ITD acute myeloid leukemia  Academic Article
• MDR₁transcript levels as an indication of resistant disease in acute myelogenous leukaemia  Academic Article
• Management of hemostatic complications in acute leukemia: Guidance from the SSC of the ISTH  Academic Article
• Methodological rigor lacking in an analysis of acute myeloid leukemia incidence and geographic distribution in Canada  Academic Article
• MicroRNA-223 dose levels fine tune proliferation and differentiation in human cord blood progenitors and acute myeloid leukemia  Academic Article
• Mismatched unrelated hematopoietic stem cell transplantation with post-transplant cyclophosphamide for high-risk acute myeloid leukemia  Academic Article
• Mitoxantrone and 5-azacytidine for refractory/relapsed ANLL or CML in blast crisis: A leukemia intergroup study  Academic Article
• Mixed acute leukaemias  Academic Article
• Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13  Academic Article
• Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin  Academic Article
• NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells  Academic Article
• Nephrotoxicity Associated with Combined Gentamicin – Amphotericin B Therapy  Academic Article
• Neuropsychological late effects of treatment for acute leukemia in children with Down syndrome  Academic Article
• Niche displacement of human leukemic stem cells uniquely allows their competitive replacement with healthy HSPCs  Academic Article
• Nonhematopoietic cells represent a more rational target of in vivo hedgehog signaling affecting normal or acute myeloid leukemia progenitors  Academic Article
• Nutrition of Children With Cancer in Brazil: A Systematic Review  Academic Article
• One-Year Survival and Prognosticators of Adults With Acute Leukemia at the Uganda Cancer Institute  Academic Article
• Outcome of patients who develop acute leukemia or myelodysplasia as a second malignancy after solid tumors treated surgically or with strategies that include chemotherapy and/or radiation  Academic Article
• Perianal Infections in Children With Acute Myeloid Leukemia: A Report From the Canadian Infection in Acute Myeloid Leukemia Research Group  Academic Article
• Pharmacokinetics and safety results from the Phase 3 randomized, open-label, study of intravenous posaconazole in patients at risk of invasive fungal disease  Academic Article
• Phase I/II study of the deacetylase inhibitor panobinostat after allogeneic stem cell transplantation in patients with high-risk MDS or AML (PANOBEST trial)  Academic Article
• Phase II study of targeted therapy with temozolomide in acute myeloid leukaemia and high-risk myelodysplastic syndrome patients pre-screened for low O⁶-methylguanine DNA methyltransferase expression  Academic Article
• Phosphorylation state of the histone variant H2A.X controls human stem and progenitor cell fate decisions  Academic Article
• Polo-like kinases in AML  Academic Article
• Predicting remission outcome in acute non-lymphocytic leukemia: General principles and their application to residual marrow leukemia  Academic Article
• Predictors and Outcomes of Viridans Group Streptococcal Infections in Pediatric Acute Myeloid Leukemia  Academic Article
• Prognosis of older patients with newly diagnosed AML undergoing antileukemic therapy: A systematic review  Academic Article
• Protooncogene expression and the clinical characteristics of acute nonlymphocytic leukemia: A Leukemia Intergroup pilot study  Academic Article
• Pyrimethamine as a Potent and Selective Inhibitor of Acute Myeloid Leukemia Identified by High-throughput Drug Screening  Academic Article
• Quality of life and physical function in adults treated with intensive chemotherapy for acute myeloid leukemia improve over time independent of age  Academic Article
• Quizartinib for the treatment of acute myeloid leukemia  Academic Article
• RNA-seq analysis of 2 closely related leukemia clones that differ in their self-renewal capacity  Academic Article
• Randomized Trials in Oncology Stopped Early for Benefit  Academic Article
• Randomized trial of high-dose cytarabine versus amsacrine in acute myelogenous leukemia in relapse: a Leukemia Intergroup Study.  Academic Article
• Re: Consolidation Therapy With Autologous Bone Marrow Transplantation in Adults With Acute Myeloid Leukemia: A Meta-analysis  Academic Article
• Real-World Treatment Patterns and Clinical Outcomes in Canadian Patients with AML Unfit for First-Line Intensive Chemotherapy  Academic Article
• Regulation of the adaptor molecule LAT2, an in vivo target gene of AML1/ETO (RUNX1/RUNX1T1), during myeloid differentiation  Academic Article
• Relation between platinum-DNA adducts and complete remission in adult acute nonlymphocytic leukemia  Academic Article
• Reprogramming of Acute Myeloid Leukemia Patients Cells: Harboring Cancer Mutations Requires Targeting of AML Hierarchy  Academic Article
• Role of Maternal Diet in the Risk of Childhood Acute Leukemia: A Systematic Review and Meta-Analysis  Academic Article
• Sam68 Allows Selective Targeting of Human Cancer Stem Cells  Academic Article
• Selection and management of older patients with acute myeloid leukemia treated with glasdegib plus low-dose cytarabine: expert panel review  Academic Article
• Simultaneous or sequential expression of lymphoid and myeloid phenotypes in acute leukemia  Academic Article
• Single nucleotide polymorphism in IL1B is associated with infection risk in paediatric acute myeloid leukaemia  Academic Article
• Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of acute myeloid leukemia cells  Academic Article
• Sodium butyrate and a T lymphocyte cell line-derived differentiation factor induce basophilic differentiation of the human promyelocytic leukemia cell line HL-60  Academic Article
• Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3–Internal Tandem Duplication Mutation (SORMAIN)  Academic Article
• Spurious detection of terminal deoxynucleotidyl transferase in phytohemagglutinin-stimulated lymphocytes  Academic Article
• Stem cell gene expression programs influence clinical outcome in human leukemia  Academic Article
• Survival outcomes and clinical benefit in patients with acute myeloid leukemia treated with glasdegib and low-dose cytarabine according to response to therapy  Academic Article
• T cell surface antigens in blast crisis of CML [letter]  Academic Article
• Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics  Academic Article
• Targeting of CD44 eradicates human acute myeloid leukemic stem cells  Academic Article
• Testicular Myeloid Sarcoma  Academic Article
• The Patterns of Fetal Haemoglobin Production in Leukaemia  Academic Article
• The Relationship of the in vivo Cell Cycle Characteristics and Treatment Outcome in Acute Myelogenous Leukemia to the Expression of the FMS and MYC Proto-Oncogenes  Academic Article
• The Role of the Plasma from Platelet Concentrates in Transfusion Reactions  Academic Article
• The histone deacetylase inhibitor valproic acid alters sensitivity towards all trans retinoic acid in acute myeloblastic leukemia cells  Academic Article
• The impact of category, cytopathology and cytogenetics on development and progression of clonal and malignant myeloid transformation in inherited bone marrow failure syndromes  Academic Article
• The low incidence of secondary acute myelogenous leukaemia in children and adolescents treated with dexrazoxane for acute lymphoblastic leukaemia: A report from the Dana-Farber Cancer Institute ALL Consortium  Academic Article
• The risk of bleeding in thrombocytopenic patients with acute myeloid leukemia.  Academic Article
• The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation  Academic Article
• The splicing factor RBM17 drives leukemic stem cell maintenance by evading nonsense-mediated decay of pro-leukemic factors  Academic Article
• The treatment of acute myelocytic leukemia in patients 30 years of age and younger  Academic Article
• The treatment of patients with newly diagnosed poor prognosis acute myelogenous leukaemia: response to treatment and treatment failure  Academic Article
• Transfusion-related Iron Overload in Children With Leukemia  Conference Paper
• Treatment outcomes for newly diagnosed, treatment-naïve TP53-mutated acute myeloid leukemia: a systematic review and meta-analysis  Academic Article
• Ultrasound Imaging of DNA-Damage Effects in Live Cultured Cells and in Brain Tissue  Academic Article
• Undetectable leukemic blasts and absence of NOD/SCID leukemia-initiating cells in cord blood from a case of maternal AML  Academic Article
• Unleashing Blocked Apoptosis in Cancer Cells: New MCL1 Inhibitors Find Their Groove  Academic Article
• Use of the day 6 bone marrow to alter remission induction therapy in patients with acute myeloid leukaemia: a leukemia intergroup study  Academic Article
• Very long chain fatty acid metabolism is required in acute myeloid leukemia  Academic Article
• XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in Leukemia and Solid Tumors  Conference Paper
• β2 integrin–derived signals induce cell survival and proliferation of AML blasts by activating a Syk/STAT signaling axis  Academic Article