Hemoglobin abnormalities in neoplastic hematological disorders. Academic Article uri icon

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abstract

  • Fetal hemoglobin (F) and hemoglobin A(2) were estimated in 35 patients with malignant hematological disorders. In 9 out of 10 patients with morphological and cytochemical features of acute myeloblastic leukemia the hemoglobin F was greater than 2%. Of the other 25 patients investigated only one patient with polycythemia rubra vera had a hemoglobin F level of more than 2%. Estimation of fetal hemoglobin may be of value in the classification of acute leukemias and the increased level observed probably reflects disturbed hemoglobin synthesis in the acute myeloblastic type.

publication date

  • April 7, 1973