Journal article
The Patterns of Fetal Haemoglobin Production in Leukaemia
Abstract
Elevated levels of haemoglobin F (Hb F) have been foudn in a wide range of haematological malignancies, but very high levels were found only in juvenile chronic myeloid leukaemia (JCML), and erythroleukaemia occurring in infancy. In both these disorders a reversion to a fetal form of erythropoiesis may occur, as judged by both the structure of the Hb F and by the disappearance of Hb A2 and the carbnoic-anhydrase isozymes during the course of …
Authors
Sheridan BL; Weatherall DJ; Clegg JB; Pritchard J; Wood WG; Callender ST; Durrant IJ; McWhirter WR; Ali M; Partridge JW
Journal
British Journal of Haematology, Vol. 32, No. 4, pp. 487–506
Publisher
Wiley
Publication Date
April 1976
DOI
10.1111/j.1365-2141.1976.tb00952.x
ISSN
0007-1048