Journal article
Intensive versus less-intensive antileukemic therapy in older adults with acute myeloid leukemia: A systematic review
Abstract
To compare the effectiveness and safety of intensive antileukemic therapy to less-intensive therapy in older adults with acute myeloid leukemia (AML) and intermediate or adverse cytogenetics, we searched the literature in Medline, Embase, and CENTRAL to identify relevant studies through July 2020. We reported the pooled hazard ratios (HRs), risk ratios (RRs), mean difference (MD) and their 95% confidence intervals (CIs) using random-effects …
Authors
Chang Y; Guyatt GH; Teich T; Dawdy JL; Shahid S; Altman JK; Stone RM; Sekeres MA; Mukherjee S; LeBlanc TW
Journal
PLOS ONE, Vol. 16, No. 3,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0249087
ISSN
1932-6203